Ethylene fluorohydrin
CAS No. 371-62-0

 
 

Return to Ethylene fluorohydrin Adverse Effects

ACTIVITY: Rodenticide

Structure:

Adverse Effects:

Bone
Endocrine: Uterus
Heart
Kidney
Teratogen

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No
Other Information
Molecular Formula: C2H5 F O 
Other Names: Ethanol,
2-Fluoro-, beta-Fluoroethanol,
2-Fluoroethanol,
TL 741
Of special interest:
TOXNET profile from Hazardous Substances Data Bank
TOXIC FLUORINATED COMPOUNDS AS BYPRODUCTS OF CERTAIN BORON TRI FLUORIDE CATALYZED INDUSTRIAL PROCESSES
Authors: BEDFORD CT, BLAIR D,
STEVENSON DE
Source: NATURE; 267 (5609). 1977 335
Included on The List of Extremely Hazardous Substances US 40 CFR - CHAPTER I - PART 355 - updated October 3, 2003
Extremely Hazardous Substance. US EPA Chemical Profile. November 30, 1987.

Uses:
Ethylene Fluorohydrin is used as a rodenticide (Hayes 1982, p. 500), insecticide (Gosselin 1984, p. III-193), and acaricide (Buchel 1983, p. 177). Not registered as a pesticide in the U.S. (USEPA/Active Ingredients 1985).

Ref: Ethylene fluorohydrin. Extremely Hazardous Substance. US EPA Chemical Profile. November 30, 1987. http://www.fluorideaction.org/pesticides/ethylene.fluorohydrin.epa87.htm

Ethylene fluorohydrin is a liquid fluoro alcohol compound which is miscible in water. Little specific data were available specifically about the toxicity of ethylene fluorohydrin; its toxicity is expected to be similar to that of FLUOROACETATE, as it is oxidized to fluoroacetate by tissue alcohol dehydrogenase. Ethylene fluorohydrin may be absorbed following ingestion, inhalation, or dermal contact. It is used as a rodenticide, although it is not registered for use as a pesticide in the US.

Mechanism of Action: The fluoroacetate ion is not poisonous itself but is converted to fluorocitric acid, which blocks the tricarboxylic acid cycle, an essential mechanism of energy production in mammalian cells ... This manifests itself principally in disturbed activities of the central nervous system and of the heart. [Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984.,p. III-194]

Ref: Ethylene fluorohydrin. TOXNET profile from Hazardous Substances Data Base. http://www.fluorideaction.org/pesticides/ethylene.fluorohydri.toxnet.htm


 
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