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The List of Organofluorine and Fluoride Pesticides
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Pesticide

CAS No.

Use Type

Other
Information

Adverse
Effects

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US EPA Registered

EPA Inert List
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Registered use in these countries (includes only a limited list of countries)

gamma-Cyhalothrin

see Cyhalothrin, gamma

-

-

-

Gliftor

CAS No. 8065-71-2

Rodenticide

See effects:

Blood
Brain
CNS
Kidney
Liver
Lung
Spleen

EPA Registered: No

Forbidden for use in China

Halfenprox

CAS No. 111872-58-3

Acaricide,
Insecticide
(Pyrethroid)

PAN Data

As of October 2003: Lttle toxicoloigical data available

Note from FAN:

Both bromine and fluorine are in the chemical formula for this substance. Studies on its effect on the brain need to be performed. (EC)

EPA Registered: No

Registered use in:
Japan, Taiwan, Vietnam

European Commission: Not allowed to be used as an active ingredient after July 25, 2003.

China: Papayas, Pears, Tea, Wax Apples

Japan: Apple, Grapefruit, Lemon, Lime, Natsudaidai (whole), Orange, Other Citrus fruits, Tea, Unshu orange

Taiwan: Pears, Wax apples

Halosafen

CAS No. 77227-69-1

Herbicide
(Amide;
Nitrophenyl ether)

PAN Data

As of October 2003: No tox data available EPA Registered: No

Haloxydine

CAS No. 2693-61-0

Herbicide
(Pyridine)

WHO: believed
obsolete or
discontinued

PAN Data

As of October 2003: No tox data available

EPA Registered: No

Haloxyfop

CAS No. 69806-34-4

Herbicide (Aryloxyphenoxy propionic acid)

PAN Data

See effects

Blood
Endocrine: Thyroid
Kidney
Liver

EPA Registered: No

US Tolerances:
Pending, foreign use

Registered use in:
Denmark, Hungary

European Commission: after July 25, 2003, only allowed in Denmark for use on Seed grass fields of red fescue and seed beds of ornamentals.

Haloxyfop-etotyl

CAS No. 87237-48-7

Herbicide
(Aryloxyphenoxy propionic acid, Glycol Ether)

PAN Data

See effects

Body Weight Decrease
Bone
Cancer: Carcinogenic effects in mice even at very low doses
Embryotoxic
Endocrine: Vaginal
Teratogenic
Urinary tract

A 1992 Greenpeace report contains case studies on 5 dangerous pesticides, including this one, that have never been registered in the US but are made in the US for export. Greenpeace argues for an end to the loopholes which allow a double standard between domestic and export pesticides.

US Tolerances: Pending, foreign use

Registered use in:
Denmark, Madagascar 

Banned in Norway

Haloxyfop-methyl

CAS No. 69806-40-2
Herbicide
(Aryloxyphenoxy propionic acid)

PAN BAD ACTOR
- Carcinogen

See effects

Body Weight Decrease
Bone
Cancer: Probable Human Carcinogen - LIVER
Cholesterol
Endocrine: Testicular
Endocrine: Thyroid
Heart
Kidney
Liver

A 1992 Greenpeace report contains case studies on 5 dangerous pesticides, including this one, that have never been registered in the US but are made in the US for export. Greenpeace argues for an end to the loopholes which allow a double standard between domestic and export pesticides.

EPA Registered: Pending

Registered use in:
China, India, Taiwan

Taiwan:
Citrus, Dry beans, Leaf vegetables with wrapped leaves, Rice, Tea

Haloxyfop-P

CAS No. 95977-29-0

Herbicide
(Aryloxyphenoxy propionic acid)

No data available EPA Registered: No

Haloxyfop-R

CAS No. 72619-32-0

Herbicide
(Aryloxyphenoxy propionic acid)

PAN Data

No data available

EPA Registered: No

Registered use in:
Australia, Germany, Hungary, Netherlands, New Zealand, South Africa 

Australia:
Grape

3-(((Heptadecafluorooctyl)
sulfonyl)amino)-N,N,N-
trimethyl-1-
propanaminium iodide

also known as

1-Propanaminium, 3-(((heptadecafluorooctyl)sulfonyl)
amino)-N,N,N-trimethyl-, iodide

 

CAS No. 1652-63-7

EPA List 3 Inert

This chemical is in the class of perfluoroalkyl sulfonates [PFOS]. On December 9, 2002, EPA stated that the "PFOSH component of these chemical substances may be hazardous to human health and the environment."

See effects for PFOS - PFOA perfluorinated chemicals.
Apoptosis
Bladder
Blood
Body Weight
Bone
Brain
Cholesterol
Adrenal
Breast
Hypthalamus
Ovary (Estrous)
Pancreas
Prostrate
Testes
Thyroid
Thymus
Uterine
Eye
Genotoxic
G-Proteins
Heart
Kidney
Liver
Lung
Mesenteric
Lymph Nodes
Reprod/dev.
Salivary
Spleen
Teratogenic

Environmental

PFOA and PFOS are perfluoridated chemicals that are persistent in the environment. They do not hydrolyze, photolyze, or biodegrade under environmental conditions

EPA Registered: YES

EPA List 3 Inert

In response to comments from Waste Not, EPA stated on December 9, 2002, that this chemical would be removed from the Inerts list. However, EPA's updated List 3 Inerts of August 2004, includes it.

 

Hexaflumuron

CAS No. 86479-06-3

Insecticide, Termiticide,
Plant Growth
Regulator
(Benzoylurea)

PAN Data

See effects

Blood
Eye
Kidney
Liver

Environmental:

Persistent in soil

Very Toxic to Aquatic Animals

Potential for bioconcentration in aquatic organisms is very high

EPA Registered: Yes

Registered use in:
Australia, Hungary, Japan, Madagascar, Philippines, Portugal, Taiwan, US

Japan:
Apple, Cotton seed oil, Pear, Potato, Tea, Watermelon

Taiwan:
Dry bean, Melons

Hexaflurate

(Potassium hexafluoroarsenate)

CAS No. 17029-22-0

Herbicide
Wood Preservative
(Inorganic-arsenic)

PAN BAD ACTOR -
(Based on Arsenic)
Carcinogen;
Developmental or Reproductive Toxin

WHO: believed
obsolete or
discontinued

See effects

The following effects (except for Environmental) pertain to Arsenic:

Carcinogen
Reproductive

Environmental:

Highly toxic to Bees

Very toxic to aquatic organisms

EPA Registered: No

Registered use in:
Australia

Hexafluoropropene,
polymer with
tetrafluoroethylene

CAS No. 25067-11-2

EPA List 3 Inert

See effects- the effects listed below are for Tetrafluoroethylene:

Cancer: multiple organs
Kidney
Liver

EPA Registered: Yes
List 3 Inert

Registered use in: US
- Because this is an "Inert", the public is not allowed to know which crops it is used on.

Hydramethylnon

CAS No. 67485-29-4

Insecticide
(Unclassified)

PAN BAD ACTOR - Developmental or Reproductive Toxin

Prop 65:
Developmental
Toxicity
and Male Reproductive
Toxicity

EPA RED

See effects

Amyloidosis - Kidney
Blood
Body Weight Decrease (including cachexia and anorexia)
Bone
Cancer: Possible Human Carcinogen - LUNG
Endocrine: Adrenal
Endocrine: Suspected Disruptor
Endocrine: Testicular
Endocrine: Thymus
Endocrine: Uterus
Kidney
Lung
Reproductive/Developmental

Environmental:

Potential for accumulation in Fish

Fish: Highly to Very Highly Toxic

EPA Registered: Yes

Registered use in:
Australia, Canada, India, Netherlands, New Zealand, Philippines, Singapore, South Africa, Tanzania, US 

European Commission: Not allowed to be used as an active ingredient after July 25, 2003.

US:
Grass (pasture & rangeland)
Grass hay (pasture & rangeland)
Pineapple

See US food tolerances

Indoxacarb

CAS No. 173584-44-6

Insecticide
(Oxadiazine)

PAN Data

 

See effects

Anemia
Ataxia
Blood
Body Weight Decrease
Bone
Brain
CNS
Cytotoxic
Developmental
Endocrine: Thymus
Heart
Kidney
Liver
Lung
Spleen

Tremors

Environmental:

Moderately to Very High Toxic to freshwater and estuarine/marine fish and invertebrates

Risks to Bees: High Toxicities via contact routes

EPA Registered: Yes

Registered use in:
Australia, India, New Zealand, US
Africa: Burkina Faso, Cameroon, Cape Verde, Chad, Gambia, Guinea-Bissau, Mali, Mauritania, Niger, Senegal, South Africa, Taiwan, Tanzania 

US: Indoxacarb and its R-enantimomer are permitted in or on approx. 230 food commodities, including:
Apple, Brassica, Cattle, Corn, Goat, Hog, Horse,
Lettuce (head & leaf), Milk, Milk fat, Pear, Sheep, Vegetables (fruiting group)

See US food tolerances

Experimental Use Permit:
Cherry (sweet & tart) to May 2007

Peaches from May 2003 to May 2006

Time-limited tolerances:
Collards to June 2006
Cranberry to Dec 2007

Isoxaflutole

CAS No. 141112-29-0

Herbicide
(Unclassified)

PAN BAD ACTOR - Carcinogen

Prop 65: Cancer

See effects

Amyloidosis - Systemic
Blood

Body Weight Decrease

Bone
Cancer: Probable Human Carcinogen - LIVER, THYROID
Cholesterol
Endocrine: Pituitary - disruption in the thyroid-pituitary hormonal feedback mechanisms
Endocrine: Thyroid
Eye
Liver
Lymph node
Sciatic nerve

Environmental:

Very Phytotoxic

Expected to Persist and Accumulate in surface and groundwater

Highly toxic to Mysid Shrimp

EPA Registered: Yes

Registered use in:
Australia, Canada, Germany, Hungary, Netherlands, Portugal, US
Africa: Burkina Faso, Cameroon, Cape Verde, Chad, Gambia, Guinea-Bissau, Mali, Mauritania, Niger, Senegal, South Africa

US and Canada:
Cattle, Corn, Egg, Goat, Hog,
Horse, Milk, Poultry, Sheep

US - permitted in or on 28 food commodities

See US food tolerances

Lactofen

CAS No. 77501-63-4

Herbicide
(Diphenyl ether)

PAN BAD ACTOR
- Carcinogen

US MAP

Prop 65: Cancer

See effects

Blood
Body Weight Decrease
Bone
Cancer: Probable Human Carcinogen - LIVER
Endocrine: Adrenal
Endocrine: Ovary
Endocrine: Testicular
Endocrine: Thyroid
Endocrine: Thymus
Eye
Kidney

Liver
Reproduction

Spleen

Environmental:

Phototoxic

Fish: Moderately to Highly Toxic

EPA Registered: Yes

Registered use in:
India, US, Vietnam

US:
Beans, snap, succulent (excluding limas)
Cotton, gin byproducts
Cotton, undelinted seed
Peanut
Soybean, seed  

See US food tolerances

lambda-Cyhalothrin

see Cyhalothrin, lambda

-

-

 

-

Lithium perfluorooctane
sulfonate

(LPOS)

CAS No. 29457-72-5

Insecticide,
Adjuvant
(Unclassified)

PFOS

PAN Data

See effects

Blood
Body Weight Decrease
Bone (including Cleft Palate)
Embryotoxic
Fetotoxic

Liver

Environmental:

Highly Toxic to Birds

Very Highly Toxic to Honey Bees


This insecticide is part of a group of chemicals known as PFOS. They are persistent, bioaccumulative and toxic to mammalian species at very low levels. Their health and enviromental effects only became known in 2000 when 3M "voluntarily" cancelled approx 150 PFOS chemicals.


EPA Registered: No

Registered use in:
Australia, Finland, New Zealand

Lufenuron

CAS No. 103055-07-8

Insecticide
(Benzoylurea)

PAN Data

As of October 2003: No tox data available.

EPA Registered: Yes

US FDA: Yes

Registered use in:
Australia, Hungary, India, Japan, New Zealand, Portugal, South Africa, Taiwan, US. Vietnam

Japan:
Apple, Brussel Sprouts, Cabbage, Corn, Eggplant, Grape, Grapefruit, Lemon, Lime, Loquat, Multiplying onion (inc Shallot), Natsudaidai (whole), Orange, Other citrus fruits, Pear, Pimento, Quince, Radish, Strawberry, Sugar beet, Tea, Tomato, Unshu orange, Welsh (inc Leek), Yam

Taiwan:
Chinese cabbages, Fruit vegetables, Leaf vegetables with small leaves,

MNFA

Also known as Nissol or MNAF

CAS No. 5903-13-9

Acaricide
(Unclassified)

See effects:

Blood
Body Weight Decrease
Brain
Endocrine: Testes
Heart
Kidney
Liver
Lung

EPA Registered: No

Magnesium aluminum
fluosilicate

CAS No. 1327-43-1

Insecticide

PAN Data

As of April 2003: Very little Tox info available.

EPA Registered: No


Magnesium fluosilicate

CAS No. 16949-65-8

Insecticide

PAN Data

As of April 2003: Very little Tox info available

EPA Registered: No

Mefluidide

CAS No. 53780-34-0

Herbicide,
Plant Growth
Regulator
(Anilide)

PAN Data

See Effects:

Body Weight Decrease
Developmental
Eye
Kidney
Liver
Sciatic nerve
Spleen

Enironmental:
Above the USEPA's level of concern for direct acute (listed and nonlisted) and chronic toxic exposure to mammals, birds and acute (listed and nonlisted) exposure to terrestrial and semi aquatic plants.
• Moderately persistent and mobile in terrestrial environments.
 

EPA Registered: Yes

US Tolerances: Revoked

Registered use in:
South Africa, UK, US 

Mefluidide, diethanolamine
salt

CAS No. 53780-36-2

Herbicide
(Anilide)

PAN Data

See Mefluidide above for effects
In June 2007, USEPA concluded that mefluidide DEA and potassium salts are biologically equivalent to mefluidide and thus they share the same toxicity as the free mefluidide.

EPA Registered: Yes

Registered use in: US

Mefluidide, potassium salt

CAS No. 83601-83-6

Herbicide
(Anilide)

PAN Data

See Mefluidide above for effects
In June 2007, USEPA concluded that mefluidide DEA and potassium salts are biologically equivalent to mefluidide and thus they share the same toxicity as the free mefluidide.

EPA Registered: Yes

Registered use in: US

Metaflumizone

CAS No. 139968-49-3

Insecticide
(unclassified)

See effects

Ataxia
Blood

Body Weight Decrease
Bone
Clastogenic
Liver
Reproductive

EPA Registered: Pending
Metamifop CAS No. 256412-89-2

As of January 2006: no tox data available.

New Pesticides: May 2001

EPA Registered: No

Metflurazone

CAS No. 23576-23-0

Herbicide
(Pyridazinone)

PAN Data
(pyridazinone

As of October 2003: no tox data available

EPA Registered: No

Methalpropalin

CAS No. 57801-46-4

Herbicide
(2,6-Dinitroaniline)

PAN Data

As of April 2005: no tox data available EPA Registered: No

Methanesulfonyl
fluoride

CAS No. 558-25-8

Fumigant,
Insecticide,
Wood Preservative

Organophosphate pesticide - no longer being used

See effects

Ataxia
Blood
Brain
CNS - Irreversible inhibitor of acetylcholinesterase
Tremors/Convulsions

EPA Registered: No

2-[Methyl
(polyfluoroalkylsulfonyl )
amino]ethyl methacrylate,
polym. w. heptyl
methacrylate, butyl
methacrylate and N-
methylolacrylamide

EPA List 3 Inert

See effects for PFOS/PFOA

Apoptosis
Bladder
Blood
Body Weight
Bone
Brain
Cholesterol

Endocrine:
Adrenal

Breast
Hypthalamus
Ovary (Estrous)
Pancreas
Prostrate
Testes
Thyroid
Thymus
Uterine

Eye
Genotoxic
G-Proteins

Heart

Kidney
Liver
Lung

Mesenteric
Lymph Nodes

Reprod/dev
.

Salivary

Spleen
Teratogenic


Environmental

Critical Global Contaminant

PFOA and PFOS are perfluoridated chemicals that are persistent in the environment. They do not hydrolyze, photolyze, or biodegrade under environmental conditions


Class Action lawsuit against DuPont and a local water company for contaminated drinking water supplies containing a PFOA chemical known as C8.

Contamination incident that led to the death of 260 cattle in West Virginia from C8 wastes.

EPA Registered: Yes

US EPA List 3 Inert

Registered use in: US
- Because this is an "Inert", the public is not allowed to know which crops it is used on.

2-[Methyl [(perfluoroalkyl)alkyl(C2-
C8)sulfonyl]
amino]alkyl(C2-C8)

acrylate„alkyl(C2-C8)
methacrylates- N-
methylolacrylamide
copolymer

Former EPA Inert
used as a
Water Repellant
Agent

EPA Registered: No

Former US EPA List 3 Inert

Metofluthrin

CAS No. 240494-70-6

Insecticide
(pyrethroid ester)

PAN Data  

New pesticide in October 2002.
As of April 2005: No tox data available.

EPA Registered: No

Registered use in:
Singapore
Experimental use (2004) in
Lombok Island, Indonesia.

Mipafox

CAS No. 371-86-8

Acaricide,
Insecticide
(Organophosphate)

WHO: believed
obsolete or
discontinued

PAN Data

See effects

Ataxia
Brain
CNS
Sciatic Nerve
Spinal Cord

Environmental:

Long half life in water at PH6 (200 days)

 

EPA Registered: No

Mono- and bis-(1 H, 1 H,
2 H, 2 H-perfluoroalkyl)
phosphates where the
alkyl group is even
numbered and in the
C6-C12 range

Former EPA Inert
used as a
Defoaming Agent

No specific data available.

See effects for PFOS/PFOA

EPA Registered: No

Former US EPA List 3 Inert
2- Naphthalenesulfonic acid,
6-amino-4-hydroxy-5-{{2- (trifluoromethyl)
phenyl}azo}-,
monosodium salt

CAS No. 67786-14-5

EPA List 3 Inert

As of October 2003: no tox data available

EPA Registered: Yes

EPA List 3 Inert

Registered use in: US
- Because this is an "Inert", the public is not allowed to know which crops it is used on.

Nifluridide

CAS No. 61444-62-0

Acaricide,
Insecticide
(Amide)

PAN Data

As of October 2003: no tox data available

EPA Registered: No

Nipyraclofen

CAS No. 99662-11-0

Herbicide
(Unclassified)

PAN Data

As of March 2005: tox data not accessible EPA Registered: No

Nissol

See MNFA

- - -

Nitrofluorfen

CAS No. 42874-01-1

Herbicide
(Nitrophenyl ether)

PAN Data

As of October 2003: no tox data available

EPA: Temporary

Norflurazon

CAS No. 27314-13-2

Herbicide
(Pyridazinone)

PAN BAD ACTOR

US MAP

EPA RED

See effects

Blood
Body Weight Decrease
Bone
Cancer: Possible Human Carcinogen - LIVER
Cholesterol
Endocrine: Ovary
Endocrine: Thyroid
Endocrine: Uterus
Kidney
Liver
Spleen

Environmental:

Groundwater Contaminant


California found norflurazon - the third most popular herbicide used on the state's roadsides - in 9.5% of the wells in 1997, the first time samples were taken.

EPA Registered: Yes

Registered use in:
Australia, New Zealand, South Africa, US

European Commission: Not allowed to be used as an active ingredient after July 25, 2003.

Australia:
Grape

US - permitted in or on 59 food commodities, including:
Alfalfa, Almond, Apple, Apricot, Asparagus, Avocado, Blackberry, Blueberry, Cattle, Cherry, Citrus Fruit, , Cotton, Filbert, Goat, Grape, Grass, Hog, Hop (fresh), Horse, Milk, Nectarine, Peach, Peanut, Pear, Pecan, Plum, Poultry, Raspberry, Sheep, Soybean, Walnut

See US food tolerances

Novaluron

CAS No. 116714-46-6

Insecticide
(Benzoylurea)

PAN Data

As of October 2003: very little tox data available.

See effects

Anemia
Blood
Body Weight Decrease

CNS
Endocrine: Testes
Liver
Reproductive and Developmental

Spleen

NOTE: Chloroaniline, p (or 4-chloroaniline) is a metabolite of Novaluron. In 2006, USEPA classified chloroaniline, p as a "Group B2 -- Probable Human Carcinogen." - SPLEEN, ADRENAL, LIVER

EPA Registered: Yes

Registered use in:
Argentina, Australia, Italy, Japan, South Africa, US

Japan:
Apple • Cabbage • Cotton seeds • Eggplant • Japanese pear • Loquat • Pear • Quince • Tomato

US: In June 2004, EPA established first-time tolerances for the residues of Novaluron in or on 65 food commodities, including:
Apple, Cattle, Eggs, Goat, Hog, Milk, Pear, Poultry, Sheep

See US food tolerances

Noviflumuron

CAS No. 121451-02-3

Insecticide
(Benzoylurea)

PAN Data

See effects

Blood
Body Weight Decrease
Bone
Brain
Cancer: LIVER, LUNG
Endocrine: Adrenal
Endocrine: Testicular
Endocine: Uterine
Eye
Kidney
Liver
Lung
Reproductive
Spleen
Stomach
Teratogen

Environmental:

Highly toxic to freshwater invertebrates

EPA Registered: Yes

Nuarimol

CAS No. 63284-71-9

Fungicide
(Pyrimidine)

PAN Data

See effects

Ataxia
Body Weight Decrease
Liver

The UK Pesticide Safety Directorate:
were advised in June 2003 that the active substance nuarimol was not being supported in the EU review programme.

EPA Registered: No

Registered use in:
Hungary, Portugal, South Africa, Taiwan, UK 

Taiwan:
Melons, Pome

Oxyfluorfen

CAS No. 42874-03-3

Herbicide
(Diphenyl ether)

US MAP

EPA RED

PAN Data

See effects

Anemia
Blood
Body Weight Decrease
Bone
Brain

Cancer: Possible Human Carcinogen - LIVER
Endocrine: Adrenal
Endocrine: Pituitary
Endocrine: Thymus
Endocrin