Return to Index
Activity: Insecticide,
Wood Preservative (Inorganic)
Structure:
Adverse Effects:
Blood
Bone
CNS
Heart
Blood
• Bone • CNS
• Heart
(click on for all pesticides)
LD50 ranges of sodium, potassium, or ammonium fluorosilicates
administered intragastrically in rats and mice were 89-128 and 45-64
mg fluoride ion/kg, respectively. Severe cornea damage was observed
3 hr after the administration of 50 mg of any of the salts into
rabbits' eyes. Min toxic dose (intragastric) of fluorosilicic acid
in rats was 8 mg/kg. Min toxic concn in 4 hr inhalation of the salt
aerosols were 7.4-9.6 mg/cu m; nontoxic concn was 0.8 mg/cu m. Main
toxic effects were decreased activities
of cholinesterase and lactate
dehydrogenase in blood serum.
The intragastric effects of the fluorosilicates were similar to
and additive with those of sodium fluoride. [Rumyantser GI et al;
Oig Sanit (11): 80-2 (1988)]
Ref: TOXNET profile from Hazardous
Substances Data Bank for AMMONIUM SILICOFLUORIDE.
http://www.fluoridealert.org/pesticides/Ammonium.Silicofluor.TOXNET.htm
Abstract:
International Chemical Safety Card. Exposure routes: inhalation
and ingestion. Short term exposure effects: irritation of the skin,
eyes and respiratory tract; effects on the calcium metabolism, resulting
in cardiac disorders and
impaired function. Long-term exposure effects: effects on the bone,
resulting in fluorosis. Threshold limit value: 2.5mg/m3 (TWA)
as fluorine (ACGIH 1997-1998).
Ref: Ref:
[Potassium hexafluorosilicate]. Source: English/French versions:
Internet documents, 1999. Spanish version: Instituto Nacional de
Seguridad e Higiene en el Trabajo, Ediciones y Publicaciones, c/Torrelaguna
73, 28027 Madrid, Spain, 1991. 2p. Illus.
As cited at Toxline at Toxnet.
|