CAS No. 137641-05-5

Return to Picolinafen Adverse Effects

ACTIVITY: Herbicide (Pyridinecarboxylic acid)

CAS Name: N-(4-fluorophenyl)-6-[3-(trifluoromethyl)phenoxy]-2-pyridinecarboxamide


Adverse Effects:

Body Weight Decrease

Endocrine: Adrenal gland

Endocrine: Thyroid


• Potential of major transformation product (CL 153815) to leach and contaminate groundwater
• The major transformation product (CL 153815) is classified as persistent in soil under anaerobic conditions

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No
Registered use in
(includes only a limited list of countries)

Australia, Canada, Germany

Other Information
Molecular Formula: C19H12 F4 N2O2 
Entry Year: 2000 
Manufacturers: Cyanamid, BASF 
Other Names: AC-900,001
Of special interest:
PAN Data 

Nov 2005 - AC 900001 (Picolinafen). Proposed Regulatory Decision Document. PRDD2005-5. This Proposed Regulatory Decision Document provides a summary of the data received and the rationale for the proposed full registration of these products. The Canadian Pest Management Regulatory Agency (PMRA) will accept written comments on this proposal up to 45 days from the date of publication of this document. Health Canada’s PMRA had previously issued a temporary registration (Regulatory Note REG2003-02) for this product with the requirement that BASF Canada Inc. carry out a poultry metabolism study and provide physicochemical data on transformation product CL 153815. These studies have now been completed.

2004 - Canada approves a Maximum Residue Limit of 0.05 ppm in barley and spring wheat (including duram). Ref: Canada Gazette, Part II, April 7, 2004.
February 17, 2003 - Canada. Regulatory Note on temporary registration. Pest Management Regulatory Agency.  
September 18, 2002 - Review report for the active substance picolinafen. European Commission Health & Consumer Protection Directorate-General.  
November 2000 - Evaluation of the new active Picolinafen in the products Sniper Herbicide & Paragon Herbicide - National Registration Authority for Agricultural and Veterinary Chemicals, Australia.  
July 1999 - Acknowledgement of dossier submitted by Cyanamid Agro NV/SA in the Official Journal of the European Communities.
August 2001- IR-4 New Products/Transitional Solution List - This list contains brief descriptions of numerous new pest control materials that have been introduced over the last several years. Additionally, it contains information on some "older" crop protection chemicals that are believed to have room for new uses. This List includes: Picolinafen 
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