http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14745180&dopt=Abstract
Biosci Biotechnol Biochem. 2004
Jan;68(1):170-4.
Metofluthrin: a potent new synthetic
pyrethroid with high vapor activity against mosquitoes.
Ujihara K, Mori T, Iwasaki T, Sugano
M, Shono Y, Matsuo N.
Agricultural Chemicals Research Laboratory, Sumitomo
Chemical Co., Ltd, Hyogo, Japan. ujihara@ssc.sumitomo-chem.co.jp
(1R)-trans-Norchrysanthemic acid fluorobenzyl esters are synthesized
and their structure-activity relationships are discussed. These
esters show outstanding insecticidal activity against mosquitoes.
In particular, the 2,3,5,6-tetrafluoro-4-methoxymethylbenzyl
analog (metofluthrin) exhibits the highest potency, being approximately
forty times as potent as d-allethrin in a mosquito coil formulation
when tested against southern house mosquitoes (Culex quinquefasciatus).
Metofluthrin also exhibits a significant vapor action at room
temperature.
PMID: 14745180 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15532930
J Am Mosq Control Assoc. 2004
Sep;20(3):292-8.
Laboratory and field evaluation of spatial
repellency with metofluthrin-impregnated paper strip against
mosquitoes in Lombok Island, Indonesia.
Kawada H, Maekawa Y, Tsuda Y, Takagi
M.
Department of Vector Ecology and Environment, Institute of
Tropical Medicine, Nagasaki University, Nagasaki, Nagasaki 852-8523,
Japan.
Spatial repellency of a new multilayer paper strip impregnated
with metofluthrin, a newly synthesized pyrethroid, was evaluated
in the laboratory and in the field at Kerandangan, Lombok Island,
Indonesia, with the use of cow- and human-baited double nets.
Spatial repellency was observed in both cow- and human-baited
collections. Metofluthrin treatment reduced mosquito collection
by >80% during the 1st 4 weeks. However, repellency seemed
to reduce with the loss of metofluthrin by evaporation within
6 wk after treatment.
Publication Types:
• Evaluation Studies
PMID: 15532930 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15669387
J Am Mosq Control Assoc. 2004
Dec;20(4):434-7.
Erratum in:
• J Am Mosq Control Assoc. 2005 Mar;21(1):105.
Trial of spatial repellency of metofluthrin-impregnated
paper strip against Anopheles and Culex in shelters without
walls in Lombok, Indonesia.
Kawada H, Maekawa Y, Tsuda Y, Takagi
M.
Department of Vector Ecology & Environment, Institute of
Tropical Medicine, Nagasaki University, Nagasaki, Nagasaki 852-8523,
Japan.
Trials of metofluthrin-impregnated multilayer paper strips
against mosquitoes in shelters with no walls were carried out
at 3 sites in Lombok, Indonesia. Major reductions in human biting
by Culex quinquefasciatus, Anopheles balabacensis, and An. sundaicus
were achieved. The device is a very practical measure of preventing
outdoor mosquito biting, with no need for electricity or heating
to evaporate its active ingredient.
PMID: 15669387 [PubMed - indexed for MEDLINE]
