Note
from EC:
For
convenience, the boxes below hightlight the fluorine and organofluorine
substances included in this Notice:
Inert
Ingredients Currently Used: |
EPA
Inerts |
Substance |
Synonym
(FYI) |
CAS
No. |
List
2 |
1,1-Difluoromethane
|
1,1-Difluoroethane |
75-37-6 |
List
2 |
Dichloromonofluoromethane |
Dichlorofluoromethane
(Dichloromonofluoromethane) |
75-43-4 |
List
2 |
Chlorodifluoromethane
|
HCFC-22 |
75-45-6 |
List
2 |
1-Chloro-1,1-difluoroethane
|
HCFC-142b |
75-68-3 |
List
2 |
Trichlorofluoromethane
|
Freon
11 |
75-69-4 |
List
2 |
Dichlorodifluoromethane
|
Freon
12 |
75-71-8 |
List
2 |
Trichlorotrifluoromethane
|
Freon
113; CFC-113 |
76-13-1 |
Inert
Ingredients No Longer Used in Pesticide Products: |
EPA
Inerts List: |
Substance |
CAS
No. |
List
2 |
Dichlorotetrafluoroethane (Syn. Cryofluorane) |
76-14-2 |
List
3 |
Carbon tetrafluoride |
75-73-0 |
List
3 |
Sodium
bifluoride |
1333-83-1 |
List
3 |
Potassium
N-ethyl-N-[(heptadecafluorooctyl)sulfonyl] glycinate |
2991-51-7 |
Also see EPA Lists of Inerts online as ofApril 2005: http://www.epa.gov/opprd001/inerts/lists.html
http://www.epa.gov/fedrgstr/EPA-PEST/1998/June/Day-24/p16571.htm
[Federal Register: June 24, 1998 (Volume 63, Number 121)]
[Notices]
[Page 34384-34390]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr24jn98-86]
-----------------------------------------------------------------------
ENVIRONMENTAL PROTECTION AGENCY
[OPP-36192; FRL-5792-3]
Inert Ingredients No Longer Used in Pesticide Products
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: EPA is removing certain chemicals from its list of pesticide
product inert ingredients that are not currently used in pesticide
products. Future use of these chemicals as inert ingredients in
pesticide products will not be permitted unless a petitioner or
registrant satisfies all data requirements as identified by the Agency,
and the Agency is able to make a determination that the use of the
inert ingredient will not pose unreasonable risk to human health or the
environment. All tolerances or exemptions from the requirement of a
tolerance for the use of these chemicals as inert ingredients in food-
use pesticide formulations will be proposed for revocation at a later
date in a separate Federal Register Notice.
DATES: This notice is effective on June 24, 1998. This notice is
subject to revision if comments are received and revision is warranted.
Comments must be received on or before August 24, 1998.
ADDRESSES: By mail, submit written comments to: Public Information and
Records Integrity Branch, Information Resources and Services Division
(7502C), Office of Pesticide Programs, Environmental Protection Agency,
401 M St., SW., Washington, DC 20460. In person, deliver comments to:
Rm. 119, CM #2, 1921 Jefferson Davis Highway, Arlington, VA.
Comments and data may also be submitted electronically to: opp-
docket@epamail.epa.gov. Follow the instructions under Unit VII of this
document. No Confidential Business Information (CBI) should be
submitted through e-mail.
Information submitted as a comment concerning this document may be
claimed confidential by marking any part or all of that information as
CBI. Information so marked will not be disclosed except in accordance
with procedures set forth in 40 CFR part 2. A copy of the comment that
does not contain CBI must be submitted for inclusion in the public
record. Information not marked confidential will be included in the
public docket by EPA without prior notice. The public docket is
available for public inspection in Rm. 119 at the Virginia address
given above, from 8:30 a.m. to 4 p.m., Monday through Friday, excluding
legal holidays.
FOR FURTHER INFORMATION CONTACT: By mail: Treva Alston, Minor Use,
Inerts, and Emergency Response Branch (MUIERB), Registration Division
(7505W), Office of Pesticide Programs, Environmental Protection Agency,
401 M St., SW., Washington, DC 20460. Office location, telephone, and
e-mail address: 2800 Crystal Drive, North Tower, Arlington, VA, (703)
308-8373, e-mail: alston.treva@epamail.epa.gov.
SUPPLEMENTARY INFORMATION: This notice announces those List 1, List 2
and List 3 inert ingredients that are no longer used in pesticide
products.
I. Background
On April 22, 1987, EPA announced certain policies designed to
reduce the potential for adverse effects from the use of pesticide
products containing toxic inert ingredients (52 FR 13305). In
developing the policy, the Agency reviewed the available data on
chemicals used as inert ingredients, and concluded that some inert
ingredients had potentially significant long-term health and
environmental hazards
[[Page 34385]]
associated with their use in pesticide products.
The 1987 notice categorized all inert ingredients into four lists,
according to toxicity, as follows: List 1 inert ingredients, described
as ``inerts of toxicological concern,'' were so categorized on the
basis of toxicological or adverse ecological effects which had been
documented in studies subject to peer review. List 2 inert ingredients,
``potentially toxic inerts/high priority for testing,'' are
structurally similar to chemicals known to be toxic and may have data
suggesting a basis for concern. List 3 inert ingredients, ``inerts of
unknown toxicity,'' do not have data supporting their inclusion on
Lists 1 or 2 (or 4; see below). List 4 inert ingredinets, ``minimal
hazard or risk inerts,'' consists of ingredients which are generally
regarded as innocuous.
In a susubsequent Federal Register notice, EPA further revised List
4, creating two subcategories: (1) List 4A, ``inerts generally regarded
as safe'' and (2) List 4B, ``inerts for which EPA has sufficient
information to reasonably conclude that the current use pattern in
pesticide products will not adversely affect public health or the
environment'' (54 FR 48314, November 22, 1989). The Agency further
revised List 4A in 1994 (59 FR 49400, September 28, 1994)(FRL-4872-5),
and continues to evaluate the toxicity of inert ingredients. EPA's
designation of inert ingredients according to list has been published
as the ``List of Pesticide Product Inert Ingredients'' ( May 17, 1995),
and is available through the Office of Pesticide Program's Public
Information and Record Integrity Branch at the address given above.
The criteria used for placement of inert ingredients on List 1 were
discussed in detail in the November 22, 1989 Federal Register notice
(54 FR 58314). In summary, the criteria for inclusion on List 1
included carcinogenicity, adverse reproductive effects, neurotoxicity
or other chronic effects, developmental toxicity (birth defects),
adverse ecological effects or the potential for bioaccumulation. Inert
ingredients which were placed on List 2 were considered to be
structurally similar to chemicals known to be toxic or there existed
data which suggested a basis for concern about the toxicity of the
chemical.
II. Inert Ingredients no Longer Used in Pesticide Products
The Agency has identified certain List 1, List 2, and List 3 inert
ingredients that are no longer used in pesticide products. Many List 1
inert ingredients are no longer used because of data call-in notices
issued pursuant to section 3(c)(2)(B) of FIFRA. In response to the
issuance of data call-in notices (DCIs) for List 1 inert ingredients,
most registrants of products containing List 1 inert ingredients chose
to respond to the DCI by canceling the registration or reformulating
the product to remove the List 1 inert ingredient.
List 1 inert ingredients which are no longer used in pesticide
products are identified as follows (with chemical name and Chemical
Abstracts Service (CAS) Registry Numbers:
List 1 Inert Ingredients No Longer Used In Pesticide Products
------------------------------------------------------------------------
CAS Reg. No. Chemical Name
------------------------------------------------------------------------
56-23-5.............................. Carbon tetrachloride
56-35-9.............................. Tributyltin oxide
62-53-3.............................. Aniline
67-66-3.............................. Chloroform
68-12-2.............................. Dimethylformamide
74-87-3.............................. Methyl chloride
75-09-2.............................. Methylene chloride
75-56-9.............................. Propylene oxide
78-87-5.............................. 1,2-Dichloropropane
79-00-5.............................. 1,1,2-Trichloroethane
79-01-6.............................. Trichloroethylene
90-43-7.............................. o-Phenylphenol
106-46-7............................. p-Dichlorobenzene
106-89-8............................. Epichlorohydrin
107-06-2............................. Ethylene dichloride
109-86-4............................. Ethylene glycol monomethyl ether
110-54-3............................. n-Hexane
110-80-5............................. Ethylene glycol monethyl ether
111-15-9............................. Ethanol ethoxyacetate
123-91-1............................. Dioxane
127-18-4............................. Perchloroethylene
140-88-5............................. Ethyl acrylate
302-01-2............................. Hydrazine
569-64-2............................. Malachite green
591-78-5............................. Methyl n-butyl ketone
1330-78-5............................ Tri-orthocresylphosphate (TOCP)
1332-21-4............................ Abestos fiber
1588-01-9............................ Sodium dichromate
26471-62-5........................... Toluene diisocyanate
No CAS Number........................ Cadmium compounds
No CAS Number........................ Lead compounds
No CAS Number........................ Pyrethrins
------------------------------------------------------------------------
List 2 inert ingredients which are no longer used in pesticide
products are identified as follows (with chemical name and Chemical
Abstracts Service (CAS) Registry Numbers:
[[Page 34386]]
List 2 Inert Ingredients No Longer Used In Pesticide Products
------------------------------------------------------------------------
CAS Reg. No. Chemical Name
------------------------------------------------------------------------
74-83-9.............................. Methyl bromide
76-14-2.............................. Dichlorotetrafluoroethane
95-50-1.............................. o-Dichlorobenzene
95-76-1.............................. 3,4-Dichloroaniline
95-82-9.............................. 2,5-Dichloroaniline
101-84-8............................. Diphenyl ether
120-32-1............................. 2-Benzyl-4-chlorophenol
554-00-7............................. 2,4-Dichloroaniline
608-27-5............................. 2,3-Dichloroaniline
608-31-1............................. 2,6-Dichloroaniline
626-43-7............................. 3,5-Dichloroaniline
25168-06-3........................... Isopropyl phenols
------------------------------------------------------------------------
List 3 inert ingredients which are no longer used in pesticide
products are identified as follows (with chemical name and Chemical
Abstracts Service (CAS) Registry Numbers:
List 3 Inert Ingredients No Longer Used In Pesticide Products
------------------------------------------------------------------------
CAS Reg. No. Chemical Name
------------------------------------------------------------------------
70-55-3.............................. p-Toluenesulfonamide
74-82-8.............................. Methane
75-73-0.............................. Carbon tetrafluoride
77-85-0.............................. Trimethylolethane
79-07-2.............................. 2-Chloroacetamide
79-43-6.............................. Dichloroacetic acid
80-15-9.............................. Cumene hydroperoxide
88-58-4.............................. 2,5-Di(tert-butyl)hydroquinone
90-33-5.............................. 7-Hydroxy-4-methylcoumarin
91-44-1.............................. 2H-1-Benzopyran-2-one, 7-
(diethylamino)-4-methyl-
92-68-2.............................. Isopropylamine salt of
stearoylisopropanolamide
derivative of sulfosuccinic acid
93-69-6.............................. o-Tolyl biguanide
95-13-6.............................. 1H-Indene
98-73-7.............................. 4-tert-Butyl benzoic acid
101-81-5............................. Benzylbenzene
103-60-6............................. Propanoic acid, 2-methyl-, 2-
phenoxyethyl ester
107-68-6............................. 2-(Methylamino)ethanesulfonic
acid
107-70-0............................. 4-Methoxy-4-methyl-2-pentanone
107-87-9............................. Methyl n-propyl ketone
109-66-0............................. Pentane
110-99-6............................. Diglycolic acid
111-92-2............................. Di-n-butylamine
112-38-9............................. 10-Undecenoic acid
115-19-5............................. 2-Methyl-3-butyn-2-ol
116-02-9............................. 3,3,5-Trimethylcyclohexanol
119-64-2............................. 1,2,3,4-Tetrahydronaphthalene
120-80-9............................. 1,2-Benzenediol
122-39-4............................. Diphenylamine
123-28-4............................. Dilauryl thiodipropionate
136-23-2............................. Dibutyldithiocarbamic acid, zinc
salt
136-44-7............................. Glyceryl p-aminobenzoate
140-31-8............................. 1-Piperazineethanamine
142-58-5............................. N-(2-Hydroxyethyl)tetradecanamide
143-00-0............................. Diethanolammonium dodecyl sulfate
420-04-2............................. Hydrogen cyanamide
431-03-8............................. 2,3-Butanedione
470-82-6............................. 2-Oxabicyclo[2.2.2]octane, 1,3,3-
trimethyl-
523-80-8............................. 4,7-Dimethoxy-5-(2-propenyl)-1,3-
benzodioxole
546-68-9............................. Tetraisopropyl titanate
548-62-9............................. Methylrosaniline chloride
630-08-0............................. Carbon monoxide
650-51-1............................. Sodium trichloroacetate
683-10-3............................. Dodecylbetaine
693-98-1............................. 1H-Imidazole, 2-methyl-
822-06-0............................. Hexamethylene diisocyanate
872-10-6............................. 1,1'-Thiobispentane
921-20-0............................. Methoxy-2,4-dihydroxypentane
1113-38-8............................ Ammonium oxalate
1118-92-9............................ N,N-Dimethylcaprylamide
[[Page 34387]]
1155-74-4............................ 1-Tetradecylpyridinium bromide
1187-59-3............................ N-Methylacrylamide
1300-71-6............................ Xylenols, mixed
1313-27-5............................ Molybdenum trioxide
1314-23-4............................ Zirconium oxide
1323-47-3............................ (2-Heptadecenyl)-4-methyl-2-
oxazolinemethanol
1332-77-0............................ Potassium tetraborate
1333-83-1............................ Sodium bifluoride
1344-08-7............................ Sodium sulfide
1393-03-9............................ Quillaja
1606-85-5............................ 2,2'-[2-Butyne-1,4-
diyl(oxy)]bisethanol
1760-24-3............................ N-[3-(Trimethoxysilyl)propyl]-1,2-
ethanediamine
2050-60-4............................ Dibutyl oxalate
2050-99-9............................ Diisoamyl ketone
2156-56-1............................ Sodium dichloracetate
2224-49-9............................ Triethanolamine laurate
2386-87-0............................ 3,4-Epoxycyclohexylmethyl 3,4-
epoxycyclohexanecarboxylate
2571-88-2............................ N,N-Dimethyloctadecylamine oxide
2724-58-5............................ Methylheptadecanoic acid
2764-13-8............................ 2-Hydroxyethyl dimethyl 3-
octadecanamidopropyl ammonium
nitrate
2991-51-7............................ Potassium N-ethyl-N-
[(heptadecafluorooctyl)sulfonyl]
glycinate
3006-13-1............................ N-Ethyl-N,N-dimethyl-1-
dodecaminium ethyl sulfate
3287-06-7............................ Diphenyl decyl phosphite
3324-58-1............................ Picric acid, sodium salt
3380-34-5............................ 2,4,4'-Trichloro-2-hydroxy
diphenyl ether
3424-21-3............................ Triisopropylamine
3614-12-8............................ N-Dodecyl-N-tetradecyl beta-
alanine
3655-00-3............................ 3,3'-(Dodecylimino)dipropionic
acid, disodium salt
3921-30-0............................ Monodecyl acid phosphate
2620-53-3............................ p-Chlorophenyl N-methyl carbamate
3942-54-9............................ o-Chlorophenyl N-methyl carbamate
4110-50-3............................ Ethyl propyl thio ether
4130-35-2............................ Tri-n-decyl trimellitate
4175-37-5............................ Octyldiphenylamine
4568-28-9............................ Triethanolamine stearate
4654-26-6............................ Dioctyl terephthalate
4696-57-5............................ Barium laurate
4891-67-2............................ Isophthalic anhydride
5012-62-4............................ 2,6-Bis(1-methylheptadecyl)-p-
cresol
5145-99-3............................ Ethyl isopropyl sulfide
5394-36-5............................ 5-Ethyl-5-methylhydantoin
5434-57-1............................ Hexyl neopentanoate
6001-97-4............................ Dihexyl*ester of sodium
sulfosuccinate (* hexyl is 1-
methylpentyl)
6144-28-1............................ Dilinoleic acid
6373-07-5............................ Rhodamine B stearate
6642-07-5............................ Trichlorophene
6843-97-6............................ Dodecyldi(aminoethyl)glycine
7360-53-4............................ Aluminum formate
7376-31-0............................ Triethanolamine sulfate
7446-09-5............................ Sulfur dioxide
7585-20-8............................ Zirconium acetate
7702-01-4............................ 1H-Imidazolium, 1-(2-
(carboxymethoxy)ethyl)-1-
(carboxymethyl)-2-heptyl-4,5-
dihydro-, hydroxide, disodium
salt
7772-98-7............................ Sodium thiosulfate
7775-14-6............................ Sodium hydrosulfite
7778-50-9............................ Potassium dichromate
7783-18-8............................ Ammonium thiosulfate
7789-00-6............................ Potassium chromate
7790-62-7............................ Potassium pyrosulfate
8002-65-1............................ Neem oil
8043-44-5............................ Sodium sulforicinoleate
10039-54-0........................... Hydroxylamine sulfate
10107-99-0........................... Abietic acid, diethylene glycol
ester
10361-37-2........................... Barium chloride
12002-51-6........................... Cresylic acid, potassium salt
12007-92-0........................... Sodium pentaborate
12379-45-2........................... Isothymyl 2-chloroethyl ether
12626-51-6........................... Dodecyl sulfate, N,N-
diethylcyclohexylamine salt
12645-53-3........................... Phosphoric acid, isooctyl ester
13470-50-3........................... 2-Heptadecyl-1-methyl-1-(2-
stearoyl(amido)ethyl-2-
midazolinium methyl sulfate
13477-36-6........................... Calcium perchlorate
13701-59-2........................... Barium metaborate
[[Page 34388]]
14408-42-5........................... 2-(8-Heptadecenyl)-4-methyl-2-
oxazoline-4-methanol
14433-76-2........................... N,N-Dimethylcapramide
16090-02-1........................... Disodium 4,4'-bis(4-anilino-6-
morpholino-s-triazin-2-
ylamino)stilbene-2,2-disulfonate
16455-61-1........................... Sodium ferric ethylene diamine
di(o-hydroxyphenylacetate)
16940-66-2........................... Sodium borohydride
17123-43-2........................... N,N-Bis(2-hydroxyethyl)glycine,
sodium salt
19529-38-5........................... Diethylenetriaminepentaacetic
acid, disodium iron(III) salt
21041-93-0........................... Cobalt hydroxide
21129-18-0........................... Manganese propionate
23054-60-6........................... N-(2-Hydroxypropyl)octanamide
23054-61-7........................... N-(2-Hydroxypropyl)decanamide
25167-70-8........................... Diisobutylene
25307-17-9........................... 2,2'(9-Octadecenylimino)ethanol
26628-22-8........................... Sodium azide
26761-64-8........................... 1H-Benzimidazoledisulfonic acid,
2-heptadecyl-, disodium salt
26836-28-2........................... Bis(2-ethylhexyl)pyrophosphate
28855-27-8........................... (Dodecylmethylbenzyl) trimethyl
ammonium chloride
30346-73-7........................... Xylenesulfonic acid, potassium
salt
30399-84-9........................... Isooctadecanoic acid
30526-26-2........................... Nonylphenol dihydrogen phosphate
31711-50-9........................... Butylnaphthalene
31866-76-9........................... 1-Oxyethyl-2-stearic imidazoline
35255-48-2........................... Cyclohexanone, cyclohexylidene-
39049-04-2........................... Zirconium neodecanoate
40766-31-2........................... 1-Phenyl-1-xylylethane
53404-15-2........................... Aluminum hydroxybenzenesulfonate
53404-49-2........................... Ethylene glycol ether of pinene
53404-62-9........................... N-[alpha-
(Nitroethyl)benzyl]ethylenediami
ne, potassium salt
54585-68-1........................... 1H-Benzimidazolesulfonic acid, 2-
undecyl-, monosodium salt
56797-01-4........................... Cerium 2-ethylhexoate
60209-82-7........................... Isodecyl neopentanoate
60789-80-2........................... Citric acid, tris(triethylamine)
salt
60840-86-0........................... Oleic tetraester of
tetra(hydroxyethyl)ethylenediami
ne
60874-82-0........................... Propylammonium nitrite
61789-32-0........................... Fatty acids, coco, 2-sulfoethyl
esters, sodium salts
61789-52-4........................... Cobalt tallate
61791-32-0........................... N-(2-Cocoamidoethyl)-N-(2-
hydroxyethyl)glycine, sodium
salt
61791-33-1........................... N-(2-Aminoethyl)-N-(2-
hydroxyethyl)glycine, N-coco
acyl derivs
61792-08-3........................... Ethanol diglycine, disodium salt
64051-23-6........................... 2-Butoxyethyl dihydrogen
phosphate, diethylamine salt
64503-07-7........................... Benzyl dibromoacetate
64741-79-3........................... Coke, petroleum
67859-56-7........................... 2,3-Dihydroxypropyl 3-
(hexylthio)propionate
67859-60-3........................... Tris[(2-ethylhexyl)oxy]boroxin
68153-99-1........................... Amines, N-tallow
alkyltrimethylenedi-, dioleates
68298-14-6........................... Methyl epoxystearate, reaction
products with tetraethylene
pentamine
68334-32-7........................... Polyphosphoric acids,2-ethylhexyl
esters, sodium salts
68442-99-9........................... Manganese boron neodecanoate
68476-95-9........................... Shale
68526-90-9........................... Decyl alcohol bottoms (higher
M.W. alcohols, ethers, esters;
isodecyl alcohol)
68609-97-2........................... Alkyl(mixed C<INF>12C<INF>14) glycidyl
ether
68630-89-7........................... 6-Carboxy-4-hexyl-2-cyclohexene-1-
octanoic acid, monopotassium
salt
68877-34-9........................... N-(Nonyloxypropyl)-1,3-
propanediamine
68917-09-9........................... Ocotea oil
68987-86-0........................... Isopropylated cresol
69867-70-5........................... Triethylamine nitrilotriacetate
70191-75-2........................... Decyl phenoxybenzenedisulfonic
acid
70904-61-9........................... Amidosulfosuccinate
71113-21-8........................... [[[3-
(Dimethylamino)propyl]imino]bis(
methylene)] bisphosphonic acid,
monohydrochloride
71487-01-9........................... Di(coco alkyl) dimethyl ammonium
nitrite
74849-88-0........................... Dicyanoethyl diethylenetriamine
75212-49-6........................... Bis(2-ethylhexyl)pyrophosphate,
disodium salt
77097-78-0........................... Pyrolysis gasoline
77500-13-1........................... Bis(2-hydroxyethyl)-3-
(decyloxy)propylamine, N-oxide
78812-39-2........................... Carbamic acid, manganese salt
79660-25-6........................... Acetamide, 2,2-dichloro-N-(1,3-
dioxolan-2-ylmethyl)-N-2-
propenyl-
81099-36-7........................... 3,4,4-Trimethyloxazolidine mixt.
with 4,4-dimethyloxazolidine
85005-69-2........................... Oleic monoester of
tetra(hydroxyethyl)ethylenediami
ne
85081-53-4........................... Dodecenylsuccinic acid,
monotridecyl ester
89875-83-2........................... (Dodecylmethylxylyl) trimethyl
ammonium chloride
92257-04-0........................... Amines, C<INF>12-14 tert-alkyl, bis-[4-
[(5-chloro-2-hydroxyphenyl)azo]-
2,4-dihydro-5-methyl-2-phenyl-3H-
pyrazol-3-onato(2-)]cobaltate(1-
) (1:1)
[[Page 34389]]
103112-35-2.......................... 1H-1,2,4-Triazole-3-carboxylic
acid, 1-(2,4-dichlorophenyl)-5-
(trichloromethyl)-, ethyl ester
103213-17-8.......................... Coke, brown coal
108746-82-3.......................... Oleic diester of
tetra(hydroxyethyl)ethylenediami
ne
125972-19-2.......................... N,N-Dimethylisooctadecanamine, N-
oxide
No CAS Number........................ Dodecyl dimethyl benzyl ammonium
napthenate
No CAS Number........................ Butanamide, 4-hydroxy-, N-C<INF>6-16-
alkyl-
No CAS Number........................ Sodium n-nonyldiphenyl ether
sulfonate
No CAS Number........................ Oligoester derived by
condensation of adipic acid,
phthalic anhydride, ethylene
glycol, n-octyl alcohol and n-
decyl alcohol
No CAS Number........................ 1H-Benzimidazole-6,3'-disulfonic
acid, 2-octadecyl-1-
(phenylmethyl)-, sodium salt
No CAS Number........................ Naphthenic acid soap of N-C<INF>16-18-
alkyl trimethylendiamine
No CAS Number........................ Nickel complex of diethyl hexyl
acid phosphate
No CAS Number........................ Isopropylamine salt of
oleoylisopropanolamide
derivative of sulfosuccinic acid
No CAS Number........................ Isodecyl phenyl acid phosphate
No CAS Number........................ Tetrapropyl succinic acid
------------------------------------------------------------------------
According to Agency records, none of the above chemicals have been
used in any registered pesticide product for over two years, and in
most cases, the above chemicals have not been used as inert ingredients
in registered pesticide products for over five years. If a registrant
disputes the Agency's determination concerning inert ingredients that
are no longer used in pesticide products and still has an active
registration for a pesticide product containing one of the chemicals
identified as no longer used in pesticide products, the registrant
should immediately notify the Agency as detailed in the ``ADDRESSES''
section of this notice. The registrant should include the inert
ingredient name, CAS Reg. No. for the inert ingredient in question and
the EPA Registration Number of the pesticide product containing the
inert ingredient.
III. Policy Governing Future Use of Chemicals that are No Longer
Permitted for Use as Inert Ingredients
Because of the toxicological and other concerns associated with
List 1 and List 2 ingredients, EPA believes that registrants will have
difficulty proving to the Agency that use of products containing such
ingredients would not result in unreasonable adverse effects on human
health and the environment. Therefore, the Agency does not normally
expect to approve future applications involving the use of any of the
above List 1 or List 2 chemicals as ingredients, except in those few
cases where the applicant can clearly demonstrate through the
submission of data that the proposed use will not adversely affect
public health or the environment. Data requirements for any such future
request will be determined by the Agency on a case-by-case basis. Use
of any of the above List 3 chemicals will be considered by the Agency
under the same procedures that apply to new inert ingredients specified
in the April 22, 1987, Inert Inrgredient Policy Statement.
IV. Revocation of Exemptions from the Requirement of a Tolerance
for Chemicals No Longer Permitted for Use as Inert Ingredients
The Agency has previously revoked most of the exemptions from the
requirement of a tolerance for those List 1 inert ingredients
identified above as no longer used in pesticide products. The Agency
will propose future revocations of any remaining exemptions from the
requirement of a tolerance for all chemicals identified above as no
longer used in pesticide products.
V. List 1 and 2 Inert Ingredients Currently Used in Pesticide
Products
There are 8 List 1 inert ingredients and 52 List 2 inert
ingredients that, according to Agency records, are still used in
pesticide products. Although the Agency stated in the November 1989
Federal Register Notice that the List 1 inert ingredient formaldehyde
was no longer used in pesticide products as an inert ingredient, the
Agency has now determined that, according to its records, formaldehyde
is present in some pesticide products as an inert ingredient for use as
a formulation preservative or as a component of certain proprietary
mixtures.
Products containing formaldehyde as an inert ingredient will be
included in the reregistration process of the active ingredient,
formaldehyde since the registration standard entitled ``Guidance for
the Reregistration of Pesticide Products Containing Formaldehyde and
Paraformaldehyde'' published on May 31, 1988, stated that formaldehyde
should be categorized as an active ingredient in all products in which
it is used, including products containing formaldehyde as an inert
ingredient.
The remaining List 1 and List 2 inert ingredients are as follows:
List 1 Inert Ingredients Currently Used in Pesticide Products
------------------------------------------------------------------------
CAS Reg No. Chemical Name
------------------------------------------------------------------------
50-00-0................................ Formaldehyde
78-59-1................................ Isophorone
81-88-9................................ Rhodamine B
103-23-1............................... Dioctyl adipate
108-95-2............................... Phenol
117-81-7............................... Diethylhexylphthalate
123-31-9............................... 1,4-Benzendiol
25154-52-3............................. Nonyl phenol
------------------------------------------------------------------------
List 2 Inert Ingredients Currently Used in Pesticide Products
------------------------------------------------------------------------
CAS Reg No. Chemical Name
------------------------------------------------------------------------
71-55-6................................ 1,1,1-Trichloroethane
75-00-3................................ Chloroethane
75-05-8................................ Acetonitrile
75-37-6................................ 1,1-Difluoromethane
75-43-4................................ Dichloromonofluoromethane
75-45-6................................ Chlorodifluoromethane
75-52-5................................ Nitromethane
75-68-3................................ 1-Chloro-1,1-difluoroethane
75-69-4................................ Trichlorofluoromethane
75-71-8................................ Dichlorodifluoromethane
76-13-1................................ Trichlorotrifluoromethane
79-24-3................................ Nitroethane
80-62-6................................ Methyl methacrylate
84-66-2................................ Diethyl phthalate
84-74-2................................ Dibutyl phthalate
85-68-7................................ Butyl benzyl phthalate
88-04-0................................ p-Chloro-m-xylenol
95-14-7................................ 1,2,3-Benzotriazole
95-49-8................................ 2-Chlorotoluene
96-29-7................................ Methyl ethyl ketoxime
97-23-4................................ Dichlorophene
97-88-1................................ Butyl methacrylate
100-02-7............................... p-Nitrophenol
100-41-4............................... Ethyl benzene
102-71-6............................... Triethanolamine
106-88-7............................... Butylene oxide
108-10-1............................... Methyl isobutyl ketone
108-88-3............................... Toluene
[[Page 34390]]
108-90-7............................... Monochlorobenzene
108-94-1............................... Cyclohexanone
111-42-2............................... Diethanolamine
111-76-2............................... 2-Butoxy-1-ethanol
111-77-3............................... Diethylene glycol monomethyl
ether
111-90-0............................... Diethylene glycol monoethyl
ether
112-34-5............................... Diethylene glycol monobutyl
ether
117-84-0............................... Dioctyl phthalate
107-98-2............................... 1-Methoxy-2-propanol
124-16-3............................... 1-Butoxyethoxy-2-propanol
131-11-3............................... Dimethyl phthalate
141-79-7............................... Mesityl oxide
149-30-4............................... Mercaptobenzothiazole
1330-20-7.............................. Xylene
5131-66-8.............................. 1-Butoxy-2-propanol
25498-49-1............................. Tripropylene glycol monomethyl
ether
29385-43-1............................. Tolyl triazole
29387-86-8............................. Propylene glycol monobutyl
ether
34590-94-8............................. Dipropylene glycol monomethyl
ether
No CAS Number.......................... Petroleum hydrocarbons
No CAS Number.......................... Xylene-range aromatic solvents
------------------------------------------------------------------------
VI. Process for Future Removal of Inert Ingredients that are No
Longer Used as Inert Ingredients
As a part of its ongoing inerts strategy, the Agency will perform
future reviews of List 1, List 2, and List 3 inert ingredients to
identify those inert ingredients which are no longer used. The Agency
will issue future Federal Register notices removing those chemicals
from its list of inert ingredients. Any associated exemptions from the
requirement of a tolerance for such chemicals when used as inert
ingredients will also be revoked. The Agency will not remove any List
4A or 4B inert ingredients from its list of inert ingredients since
sufficient data have been presented to establish that the use of these
chemicals as inert ingredients will not present a hazard to public
health or the environment.
In an effort to identify inert ingredients which are no longer
used, the Agency may contact registrants of pesticide products or
manufacturers/suppliers of substances which are used as inert
ingredients in pesticide formulations which contain specific inert
ingredients the Agency believes may not actually be in use. This action
may be necessary to verify the information currently contained in the
Agency's database relative to product formulation information.
The Agency considers all alternate formulations valid for purposes
of registration unless a registrant provides specific written notice to
the Agency that a particular formulation will no longer be used.
Therefore, the Agency wants to encourage registrants as part of their
pesticide product stewardship program to provide the Agency with
written notice identifying specific formulations that are no longer
used as part of the pesticide product registration and amendment
process. This action will assist the Agency in better identifying those
inert ingredients that are no longer used in pesticide products as well
as improving the overall accuracy of the Agency's product formulation
information.
VII. Public Record and Electronic Submissions
The official record for this notice, as well as the public version,
has been established for this notice under docket control number [OPP-
36192] (including comments and data submitted electronically as
described below). A public version of this record, including printed,
paper versions of electronic comments, which does not include any
information claimed as CBI, is available for inspection from 8:30 a.m.
to 4 p.m., Monday through Friday, excluding legal holidays. The
official record is located at the Virginia address in ``ADDRESSES'' at
the beginning of this document.
Electronic comments can be sent directly to EPA at:
opp-docket@epamail.epa.gov
Electronic comments must be submitted as an ASCII file avoiding the
use of special characters and any form of encryption. Comment and data
will also be accepted on disks in Wordperfect 5.1/6.1 or ASCII file
format. All comments and data in electronic form must be identified by
the docket control number [OPP-36192]. Electronic comments on this
notice may be filed online at many Federal Depository Libraries.
List of Subjects
Environmental protection, Pesticides and pests.
Dated: June 11, 1998.
Peter Caulkins,
Acting Director, Registration Division, Office of Pesticide Programs.
[FR Doc. 98-16571 Filed 6-23-98; 8:45 am]
BILLING CODE 6560-50-F
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