FLUORIDE ACTION NETWORK PESTICIDE PROJECT

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Teflubenzuron. Pesticide Residues in Food. FAO & WHO report. 1996.

Pesticide Residues in Food - 1996.

Report Sponsored Jointly by FAO and WHO. (FAO Plant Production and Protection Paper - 140)

http://www.fao.org/docrep/W3727E/w3727e0t.htm#4.23%20teflubenzuron%20(190)%20®*

Teflubenzuron (190) (R)*

* New compound

RESIDUE AND ANALYTICAL ASPECTS

Residue and analytical aspects of the compound were considered for the first time by the present Meeting.

Teflubenzuron, 1-(3,5-dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl) urea, is a fat-soluble insecticide whose major use is for the control of a wide range of insect pests and some mites in fruits, vegetables, cereals and seeds. The Meeting received extensive information on metabolism in plants and animals, environmental fate in soil, including information on residues in rotational crops and biodegradation in water/sediment systems, methods of residue analysis, stability of residues in stored analytical samples, approved use patterns, supervised residue trials, animal transfer studies and the fate of residues during processing.

Metabolism studies on rats, lactating goats, laying hens, apples, potatoes, cotton and spinach were reviewed. Analytical methods (HPLC and GLC) are available for the determination of teflubenzuron in plant and animal materials, soil, water and air.

The Meeting evaluated residue data from supervised trials and estimated maximum residue levels for pome fruits, plums (including prunes), head cabbages, Brussels sprouts and potatoes. Insufficient data were available to estimate maximum residue levels for citrus fruits, cherries, nectarines, peaches, grapes, broccoli, cucumbers, egg plants, peppers, tomatoes, mushrooms, Chinese cabbage, soya bean seeds, forage and hay, maize, cotton seed or coffee beans. Residue data were received from supervised trials on wild blackberries, blueberries and raspberries, kiwifruit, persimmons, peas (immature seeds), alfalfa forage and green grass, but no GAP was available to evaluate the data.

Animal transfer studies in which lactating dairy cows and laying hens were fed with teflubenzuron were reviewed, but as no maximum residue levels had been estimated for feed items the studies could not be evaluated.

Processing studies were available for apples, plums, cherries, grapes, potatoes, tomatoes, soya beans and cotton, but were insufficient to estimate transfer factors.

The residue should be defined as teflubenzuron. It is fat-soluble. Estimates of STMRs and of maximum residue levels which are recommended for use as MRLs are recorded in Annex I.

FURTHER WORK OR INFORMATION

Desirable

1. Physical and chemical properties of the pure active ingredient.

2. Further processing studies on apples and plums to allow the calculation of transfer factors.