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ACTIVITY:
Herbicide
(pyrazolylphenyl)
CAS Name:
[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methyl-1H-pyrazol-3-yl]-4-fluorophenoxy]acetic
acid
NOTES:
This compound is normally used as a salt or an ester, the identity
of which should be stated, for example pyraflufen-ethyl.
Structure:
US
Federal Register
••
Note: Due to length, the following is a partial
list. Click here
to see full list of FR entries.
|
| Date
Published |
Docket
Identification Number |
Details |
| May
21, 2003 |
OPP-2003-0163 |
NICHINO
AMERICA. Pesticide
Tolerance. FINAL
RULE. This regulation establishes
a tolerance for combined residues of pyraflufen and pyraflufen-ethyl
in or on
-- Cotton, gin byproduct............ 1.5
-- Cotton, undelinted seed........0.04
-- Cancer Classification:
``Likely to be Carcinogenic to
Humans'' by the oral route Q1*
= 3.32 x 10-2 (mg/kg/day)-1
-- Inhalation1 long-term (< 6 months) Oral NOAEL= 20 1X
Mouse carcinogenicity. LOAEL = 98 mg/kg/day based
on liver toxicity.
-- Inhalation1 intermediate-term (1-6 months) Oral NOAEL=
20 1X Mouse carcinogenicity. LOAEL = 98 mg/kg/day based on
liver toxicity at interim sacrifice.
-- Inhalation1 short-term (1-30 days)
Oral NOAEL= 20 1X Developmental toxicity- rabbit. LOAEL =
60 mg/kg/day based on decreases in bwt
and food consumption, GI observations, and abortions.
-- Chronic dietary. Mouse carcinogenicity. Chronic RfD = 0.20
mg/ kg/day. LOAEL = 98 mg/kg/day. based on liver
toxicity.
-- Pyraflufen-ethyl is currently
registered for use on the following residential non-dietary
sites: Airports, nurseries, ornamental
turf, golf courses, roadsides, and railroads. |
| April
30, 2003 |
OPP-2003-0110. |
Nichino
America. Pesticide
tolerances. FINAL RULE established for combined
residues of the herbicide pyraflufen-ethyl (ethyl 2-chloro-5-(4-chloro-5-difluoromethoxy-1-
methyl-1H-pyrazol-3-yl)-4-fluorophenoxyacetate) and its
acid metabolite, E-1 (2-chloro-5-(4-chloro-5-difluoromethoxy-1-methyl-1H-
pyrazol-3-yl)-4-fluorophenoxyacetic acid)•,
expressed as the ester equivalent in or on
|
Commodity |
Parts
per million |
| Corn,
field, forage |
0.01 |
| Corn,
field, grain |
0.01 |
| Corn,
field, stover |
0.01 |
| Potato |
0.02 |
| Soybean,
forage |
0.01 |
| Soybean,
hay |
0.01 |
| Soybean,
seed |
0.01 |
-- Cancer
Classification: ``Likely
to be Carcinogenic to Humans'' by the oral route.
-- Mouse Carcinogenicity LOAEL = 98
mg/kg/day based on liver toxicty
-- Developmental toxicity- rabbit.
LOAEL = 60 mg/kg/day based on decreases
in bwt and food consumption,
GI observations, and abortions
•
--
Note from FAN; this metabolite is Pyraflufen. |
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