California Prop 65
Fluorinated pesticides known to the State
to cause C
ancer and/or Developmental and Reproductive Toxicity


As a result of a citizens initiative called Proposition 65, the California Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and republish at least once per year the list of chemicals known to the State that cause cancer or reproductive toxicity.

You can access the latest list at

FAN's compilation of Prop 65 fluorinated pesticides
Pesticide CHEMICALS KNOWN TO THE STATE TO CAUSE CAS No. Date California added to List
Acifluorfen [sodium] CANCER 62476-59-9 Jan 1, 1990
Fluazifop butyl

Developmental toxicity

69806-50-4 Nov 6, 1998
Fluorouracil Developmental toxicity 51-21-8 Jan 1, 1989
Fluvalinate Developmental toxicity 69409-94-5 Nov 6, 1998
Hydramethylnon Developmental toxicity and Male reproductive toxicity 67485-29-4 March 5, 1999
Isoxaflutole CANCER 141112-29-0 Dec 22, 2000
Lactofen CANCER 77501-63-4 Jan 1, 1989
Sodium fluoroacetate

Male reproductive toxicity

62-74-8 Nov 6, 1998

Some definitions:

Developmental Toxicity - adverse effects on the developing organism that may result from exposure prior to conception (either parent), during prenatal development, or postnatally to the time of sexual maturation. Adverse developmental effects may be detected at any point in the lifespan of the organism. The major manifestations of developmental toxicity include:
(1) death of the developing organism,
(2) structural abnormality,
(3) altered growth, and
(4) functional deficiency.
The California Proposition 65 definition (almost the same) is:
'Developmental toxicity' is defined to include adverse effects on the products of conception (i.e., the conceptus), including but not limited to: Postnatal parameters including growth and development, physiological deficits and delay, neurological, neurobehavioral and psychological deficits, altered sex ratio, abnormal sexual development or function, or morbidty or mortality.

Reproductive Toxicity - the hazard to three populations, the male, the female and the conceptus, each of which has distinct differences in toxic response and susceptibility. The conceptus is at risk from long before birth, and the risk persists long after birth (some chemicals harm only female and others only male, i.e., sperm motility, morphology).


Fluoride Action Network | Pesticide Project | 315-379-9200 |