Profluralin
CAS No. 26399-36-0
 
 

Return to Profluralin Adverse Effects

ACTIVITY: Herbicide (2,6-Dinitroaniline)

Note: WHO: Believed to be obsolete or discontinued for use as pesticides.

CAS Name: N-(cyclopropylmethyl)-2,6-dinitro-N-propyl-4-(trifluoromethyl)benzenamine

Structure:

Adverse Effects:

Carcinogen
Liver

Environmental Effects:

Toxic to Honey Bees

Very High Bioconcentration in Aquatic Organisms

Persistent in soil

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No 
US EPA PC Code: 106601 
(Old US EPA PC Code: 304300)
California Chemical Code 1897  
US Tolerances: Revoked 
FDA LMS Code: A53 
US EPA Permit Date
and Registrant:
1973, Ciba-Geigy 
Other Information
Molecular Formula: C14H16 F3 N3O4 
Manufacturers: Syngenta 
Other Names: Pregard
Tolban
CGA 10832
ER-5461
 
Former Manufacture site: US:

[Ciba-Geigy Corp] McIntosh, Ala 36553.
 
Of special interest:
PAN Data 
TOXNET profile from Hazardous Substances Data Bank 
Believed to be obsolete or discontinued for use as pesticides. WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2000-2002. Table 6. Active ingredients not included in the Classification and believed to be obsolete or discontinued for use as pesticides, p 37.
March 2000 - Cenex Supply and Marketing, Inc. (CSMI) in Quincy, Grant County, Washington, operated a liquid fertilizer and soil fumigant storage and distribution facility. Seious contamination resulted from the landspreading of pesticide sediment sludges on agricultural land. Among the many pesticides found in soil samples, three herbicides (trifluralin, vernolate, and ethalfluralin), one insecticide (chlorpyrifos), one pesticide (disulfoton), and three metals (chromium, beryllium, and cadmium) exceeded one or more health-based comparison values in CSMI soil. Profluralin was also found in soil samples. The population of Quincy is 3,715. This report characterizes the community's concerns about excess cancer and disease rates, very rare abnormalities such as Rubinstein-Taybi Syndrome, and ill health as not "unusual" - a typical ATSDR-explantion handed out to very sick communities
-- organofluorine pesticides highlighted in red.
 
March 1985 - Herbicide Profile (Tolban) - Pesticide Management Education Program (PMEP) at Cornell Univeristy 
October 2001 - Glossary of Pesticide Chemicals. A listing of pesticides subject to analysis of residues in foods and feeds by the US Food and Drug Administration. 
April 2000 - Food and Drug Administration Pesticide Residue Monitoring. - Table 3. Pesticides detectable by methods used in 1999 regulatory monitoring. 


US Federal Register
1992
The EPA has proposed to revoke the tolerances (Tolban) for residues of profluralin in or on ALFALFA; COTTONSEED; EGGS; MILK, MEAT, FAT, and MEAT BY-PRODUCTS of CATTLE, GOATS, HOGS, HORSES, POULTRY, and SHEEP; SAFFLOWER (seed); SEED and POD VEGETABLES (dry, succulent, fodder and forage); SOYBEAN (hay); and SUNFLOWER (seed). This herbicide was cancelled by the USEPA in April of 1984. Note: The Fed. Reg. does not have online access to 1992 documents. This EPA notice is from the PMEP at Cornell University.

Product Name: TOLBAN 4E HERBICIDE
US EPA Registration Number: 100- 523-AA

Status: Inactive: 13-FEB-85

Ingredients found:
1.9% of PROFLURALIN, OTHER RELATED
43.6% of PROFLURALIN
54.5% of INERT INGREDIENTS

Use: ALFALFA (FORAGE - FODDER) (ALFALFA HAY) (23001)
BEANS (ALL OR UNSPEC) (28001)
COTTON (ALL OR UNSPEC) (28007)
COTTON, GENERAL (29121)
LEGUMES & OTHER NONGRASS CROPS FOR FORAGE-FODDER (23000)
OKRA (GUMBO) (15015)
PEAS (ALL OR UNSPEC) (ALL OF UNSPEC) (28016)
PEAS, GENERAL (29127)
SAFFLOWER (ALL OR UNSPEC) (28076)
SAFFLOWER, GENERAL (29129)
SORGHUM (ALL OR UNSPEC) (28019)
SORGHUM/MILO GENERAL (29131)
SOYBEANS (ALL OR UNSPEC) (28023)
SUGARBEET (ALL OR UNSPEC) (28020)
SUGARBEET, GENERAL (29135)
SUNFLOWER (ALL OR UNSPEC) (28021)
SUNFLOWER, GENERAL (29133)

 
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