CAS No. 29091-21-2

Return to Prodiamine Adverse Effects
See Abstracts

ACTIVITY: Herbicide (2,6-Dinitroaniline)

CAS Name: 2,4-dinitro-N3,N3-dipropyl-6-(trifluoromethyl)-1,3-benzenediamine


Adverse Effects:

Body Weight Decrease
Cancer: Possible Human Carcinogen: THYROID, PANCREAS, FIBROSARCOMAS
: Suspected Disruptor
Endocrine: Thyroid

Environmental Effects:

Highly Toxic to Fish and Invertebrates

Regulatory Information
(only comprehensive for the US)
US EPA Registered: Yes 

(Old US EPA PC Code: 391200)

California Chemical Code 2236  
FDA LMS Code: 814 
US EPA Permit Date
and Registrant:
1992, Sandoz  
Registered use in
(includes only a limited list of countries)

Australia, US  
Other Information
Molecular Formula: C13H17 F3 N4O4  
Entry Year: 1975 
Inventing Company: US Borax 
Manufacturers: Syngenta, (Velsicol, Sandoz), Novartis 
Other Names: Barricade, Blockade,
Endurance, Rydex, SAN-745H
Manufacture site:


BASF, Beaumont, Texas 77705

Of special interest:
PAN Data 
Material Safety Data Sheets & Labels
1980 - 1992 - Index of US EPA Cleared Reviews  
Herbicide Products - Partial list 
October 2001 - Glossary of Pesticide Chemicals. A listing of pesticides subject to analysis of residues in foods and feeds by the US Food and Drug Administration. 

1992 - Pesticide Fact Sheet Number 231: Prodiamine. US EPA Office of Pesticide Programs. The document contains up-to-date chemical information, including a summary of the Agency's regulatory position and rationale, on prodiamine. A Fact Sheet is issued for the following action--registration of a new chemical. Order No. NTIS/PB92-145416 (14p) from the National Technical Information Service. - for details see

April 2000 - Food and Drug Administration Pesticide Residue Monitoring. - Table 3. Pesticides detectable by methods used in 1999 regulatory monitoring.

June 14, 2001 - Implementation of the Community Strategy for Endocrine Disruptors - a range of substances suspected of interfering with the hormone systems of humans and wildlife. Communication from the Commission to the Council and the European Parliament. Commission of the European Communities, Brussels COM (2001) 262 final. (More information available at: )

This document presents a "priority list of substances for further evaluation of their role in endocrine disruption. During 2000, a candidate list of 553 man-made substances and 9 synthetic/natural hormones has been identified." Organofluorine pesticides in this list include:

Substances included on the Endocrine Disruptor Liist CAS No. Substances included on the Endocrine Disruptor Liist CAS No.
Bifenthrin 82657-04-3 Flutriafol 76674-21-0
Cyhalothrin (@Karate) 91465-08-6 Fluvalinate 69409-94-5
Diflubenzuron 35367-38-5 Prodiamine 29091-21-2
Epoxiconazole - Stannane, tributylfluoro [Tributyltin fluoride] 1983-10-4
Fipronil - Thiazopyr -
Fluazifop-butyl 69806-50-4 Trifluralin -

US Federal Register
Date Published Docket Identification No. Details
Feb 22, 2006 EPA-HQ-OPP-2006-0084

Requests to Voluntarily Cancel Certain Pesticide Registrations. Unless a request is withdrawn by August 21, 2006, orders will be issued canceling these registrations. The Agency will consider withdrawal requests postmarked no later than August 21, 2006.

Registration no. Product Name Chemical Name Registrants Requesting Voluntary Cancellation
066222-00088  Prodiamine Technical 1,3-Benzenediamine, 2,6-dinitro-N1,N1- dipropyl-4-(trifluoromethyl)-

Makhteshim-Agan of North America Inc.,
4515 Falls of Neuse Rd
Ste 300,
Raleigh, NC 27609.

August 3, 2005 OPP-2005-0201

Cancellation of Pesticides for Non-payment of Year 2005 Registration Maintenance Fees.

Section 24(c) Registrations canceled for non-payment of the 2005
maintenance fee are shown in the following Table 1:

Table 1.--Section 24(c) Registrations Canceled for Non-Payment of Maintenance Fee

SLN no. Product Name
000100 CA-99-0025 Barricade 65WG Herbicide
Nov 5, 2003 OPP-2003-0340 SYNGENTA - Request for Amendments to Delete Uses in Certain Pesticide Registrations. The deletion for this request is effective on May 3, 2004.
Registrant Registration No. Product Name Delete From Label
Syngenta Crop Protection, Inc., Box 18300, Greensboro, NC 27419 000100-00834 Barricade 65WG Herbicide Plants grown for cut foliage production
Sept 7, 1995 na

SANDOZ - Request to Voluntarily Cancel "Barricade 65WG in Water Soluble Packs" - EPA Registration No. 055947-00143.

Fluoride Action Network | Pesticide Project | 315-379-9200 |