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ACTIVITY: Molluscicide
Scientific
Name: 3,5-Dibromo-2-hydroxy-N-(3-(trifluoromethyl)phenyl)benzamide
Structure:
| Note:
This pesticide contains both bromine and
fluorine; a combination
that has the potential to produce severe adverse effects - particularly
to the brain. |
| Adverse
Effects:
•
No toxicological data available. See above. |
Regulatory
Information
(only comprehensive for the US) |
| US
EPA Registered: |
No |
| US
EPA PC Code: |
027601 |
| California
Chemical Code |
1651 |
| Other
Information |
| Molecular
Formula: |
C14H8
Br2 F3 NO2 |
| Manufacturers: |
DeWitt,
ZEP Manufacturing |
| Other
Names: |
Fluorophene
3,5-Dibromo-2-hydroxy-N-(3-(trifluoromethyl)phenyl)benzamide
3,5-Dibromo-3'-(triflouromethyl)salicylanilide
3,5-Dibromo-3'-(trifluoromethyl)salicylanilide
3,5-Dibromo-alpha,alpha,alpha-trifluoro-m-salicylotoluidide
BRN 1155294
Benzamide, 3,5-dibromo-2-hydroxy-N-(3-
(trifluoromethyl)phenyl)-
Caswell No. 290
EINECS 225-322-0
Faultless
Fabric Finish with Sansium
Flusalan
Flusalanum
Flusalanum [INN-Latin]
NSC 166520
Vancide FP
Witexo
Antibacterial Waxless
Floor
Finish
Witt-o-last
Zepermex
|
| Of
special interest: |
| PAN
Data |
| List
of 4 discontinued products |
| Abstracts/Reports: |
From
Toxline at Toxnet
Standards
for nonprescription germ killers
Authors: Hecht A
Author Address: FDA, 5600 Fishers Lane, Rockville, MD 20857
Source: FDA Consum.; VOL 12 ISS Jul-Aug 1978,
P15-17, (REF )
Abstract: The Food and Drug Administration's tentative standards
for a variety of over-the-counter drugs that are used to kill
germs on the skin are discussed including 5 ingredients, hexylresorcinol,
benzalkonium chloride, benzethonium chloride, methylbenzethonium
chloride, and poloxamer 188 which have been found safe and
effective for cleansing superficial skin wounds. The
standards are based largely on the work of an advisory panel
whose findings led to the banning of hexachlorophene, tribromsalan,
and fluorosalan [synonym for Fluorophene]. |
ORGANO BROMIDES IODIDES
AND FLUORIDES CLASS STUDY WITH COVER LETTER DATED 07/01/81
Corporate Name: CHEM SELECTION WORKING GROUP
Source: EPA/OTS; Doc #40-8134106
Keywords:
SRI INTERNATIONAL
FLUOROALKENES
ENVIRONMENTAL FATE
PRODUCTION AND PROCESS
Order Number:
NTIS/OTS0523797 |
| http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=5170693&dopt=Abstract
Rev Bras
Malariol Doencas Trop 1971 Jan-Dec;23(1):41-9
[Molluscacide
action of fluorophene and diaphene in the presence of solids
in water suspension]
No Abstract available
[Article in Portuguese]
de Souza CP, Paulini E. |
| http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4744906&dopt=Abstract
Helv
Odontol Acta 1973 Oct;17(2):105-8
Topical
gels containing Chlorhexidine, Vantocil, Fluorophene and animal
caries.
No Abstract available
Tikus HW. |
| http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4744911&dopt=Abstract
Helv
Odontol Acta 1973 Oct;17(2):99-103
Chlorhexidine,
Vantocil, Fluorophene and antimycotic agents in an animal
caries test.
No Abstract available
Muhlemann HR. |
| http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7328586&dopt=Abstract
J Med
Chem 1981 Oct;24(10):1245-9
Potential
salicylamide antiplaque agents: in vitro antibacterial activity
against Actinomyces viscosus.
Coburn RA, Batista AJ, Evans RT, Genco
RJ.
A series of 55 salicylamides, including 3,5-dibromo-, 5-n-alkyl-,
and 5-n-acylsalicyloyl derivatives of various anilines, heterocyclic
amines, benzylamines, and alkylamines, was synthesized and
evaluated for in vitro antibacterial activity against Actinomyces
viscosus, an adherent oral microorganism implicated in periodontal
disease. The in vitro minimum inhibitory concentrations of
15 4'-bromosalicylanilides were found to correlate (r = 0.92)
with estimated log D values. Several nonhalogenated salicylanilides,
such as 5-n-hexyl- (40) and 5-n-decanoyl-4'-nitrosalicylanilide
(47), were found to exhibit higher levels of in vitro antibacterial
activity against a number of Actinomycetes than did tribromsalan
(1) or fluorophene (2). |
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