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Return
to Fomesafen, sodium Index Page
Activity:
Herbicide
Structure
for "Fomesafen"
Adverse
Effects:
Cancer:
Possible Human Carcinogen - LIVER
• SEE ALSO: FOMESAFEN
US:
As of September 13, 2003, residues of Fomesafen and its sodium
salt are permitted in or on
soybean in
the United States. |
Cancer:
Possible Human Carcinogen - LIVER
(click
on for all fluorinated pesticide)
There are eight diphenyl ethers that are structurally similar
to diclofop-methyl. Of the chemicals, fomesafen
sodium, haloxyfop-methyl (Verdict), oxyfluorfen, acifluorfen
sodium, nitrofen, and lactofen were reviewed in the initial CPRC
report. All of these chemicals induced liver
adenomas and carcinomas in rats and/or mice. Except for
haloxyfop-methyl, all of the other chemicals
produced positive results in at least one of the mutagenicity
assays... For fomesafen (P.C.Code 123802)
the data included, a 4-week feeding study in the mouse (MRID 40786709),
a 28-day feeding study in the hamster (MRID 40910801) and an in
vitro study (MRID 40910802, Elcombe et al., Annals NY Acad Sci.
804: 628-635 [1996]) with rat, mouse, guinea pig and human hepatocytes...
May
24, 2000 - Cancer
Assessment Document. Evaluation of the
Carcinogenic Potential of Diclofop-Methyl. (Second Review). Final
Report. Cancer Assessment Review Committee, Health Effects Division,
US EPA Office of Pesticide Programs.
Note:
Except for Nitrofen, all the pesticides cited above are fluorinated.
Possible
Carcinogen [Liver]
Ref: PAN Pesticides Database.
http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC35964
See
also Fomesafen
A
February
17, 2005,
check at the Code
of Federal Regulations for the Sodium
salt of fomesafen: this herbicide
is permitted in or on 1
food
commodity in the United States.
Note:
•
In 2003, the CFR listed both Fomesafen (CAS No. 72178-02-0)
and the Sodium salt of fomesafen with a tolerance of 0.05
ppm on Soybean.
•
EPA grants several Emergency Exemptions for the use of "Fomesafen"
- see examples.
|
| [Code
of Federal Regulations]
[Title 40, Volume 22]
[Revised as of July 1, 2004]
From the U.S. Government Printing Office via GPO Access
[CITE: 40CFR180.433]
[Page 447]
TITLE 40--PROTECTION OF ENVIRONMENT
CHAPTER I--ENVIRONMENTAL PROTECTION AGENCY (CONTINUED)
PART 180_TOLERANCES AND EXEMPTIONS FROM TOLERANCES FOR PESTICIDE
CHEMICALS
IN FOOD--Table of Contents
Subpart C_Specific Tolerances
Sec. 180.433 Sodium salt of fomesafen; tolerance for residues.
(a) General. Tolerances are established for the residues of
sodium
salt of fomesafen, 5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-
(methylsulfonyl)-2-nitrobenzamide, in
or on soybean at 0.05 part per
million.
(b) Section 18 emergency exemptions. [Reserved]
(c) Tolerances with regional registrations. [Reserved]
(d) Indirect or inadvertent residues. [Reserved] |
| Commodity |
As
of
September 13,
2003
PPM |
As
of
February 17,
2005
PPM |
CFR |
| Soybean |
0.05 |
0.05 |
180.433
|
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