Adverse Effects
Ammonium silicofluoride
CAS No. 16919-19-0
 
 

Return to Ammonium silicofluoride Index Page

Activity: Insecticide, Miticide, Wood preservative, EPA List 3 Inert (Inorganic)
Also known as Ammonium fluosilicate
Structure:

Adverse Effects:
Blood
Body Weight Decrease
Bone
CNS
Tremors/Convulsions
Environmental

Note: Very little toxicological information available.

Major Uses:

-- /FORMER USE:/ INSECTICIDE /DRI-DIE/ [Farm Chemicals Handbook 88. Willoughby, Ohio: Meister Publishing Co., 1988.,p. C-87]

-- WOOD PRESERVATIVE

-- IN PROPHYLACTIC DENTAL PREPARATION [CANADIAN PATENT 971108 (JULY 15, 1975) KENDALL COMPANY]

-- Insecticide and miticide, repellent or feeding depressant for carpet beetles and clothes moths. /Laidlaw U-San-O Moth Proofing Spray/ [Purdue University; National Pesticide Information Retrieval System (1988)]

-- Insecticide and miticide for fleas on dogs and cats, German cockroaches, oriental cockroaches, and drywood termites. /Superior Dri-Die/ [Purdue University; National Pesticide Information Retrieval System (1988)]

-- Insecticide and miticide for lice and fleas on cats and dogs, silverfish, ants, German cockroaches, and oriental cockroaches. /Bye Bugs/ [Purdue University; National Pesticide Information Retrieval System (1988)]

-- In pesticides; in soldering flux; etching glass. [Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996. 91]

-- Laundry sours, mothproofing, disinfectant in brewery industry, glass etching, light metal casting, electroplating. [Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993 66]

Manufacturer:

-- Elf Atochem North America, Inc., Hq, 2000 Market Street, 21st Floor, Philadelphia, PA 19103-3222, (215) 419-7000; Industrial Specialties Division; Production site: 5101 West 21st Street, Tulsa, OK 74107, (918) 583-0851. [SRI. 1997 Directory of Chemical Producers - United States of America. Menlo Park, CA: SRI International 1997. 455]

Ref: TOXNET profile from Hazardous Substances Data Bank.
http://www.fluorideaction.org/pesticides/ammonium.silicofluor.toxnet.htm


Body Weight Decrease (click on for all fluorinated pesticides)

Chronic: Causes severe skin irritation and burns. Ingestion or inhalation may be harmful and possibly fatal depending on severity and length of over-exposure. Chronic over- exposure may cause fluorosis. Product may be absorbed through the skin and produce signs of fluorosis such as weight loss, brittleness of bones, anemia, weakness and stiffness of joints. Internal bleeding may develop. First aid procedures should be followed even in cases of suspected contact.
Ref: Ammonium fluorosilicate Material Safety Data Sheet from LCI, Ltd.
http://www.fluorideaction.org/pesticides/ammonium.fluosilicate.msds.htm

Blood and CNS (click on for all fluorinated pesticides)

-- Human Toxicity Excerpts: SYMPTOMATOLOGY: A. Ingestion of soluble fluoride salts. 1. Salty or soapy taste, salivation, nausea. Repeated small doses (as in drinking water) may produce no other symptoms, but polyuria and polydipsia have also been reported. 2. Large doses lead promptly to burning or crampy abdominal pain, intense vomiting and diarrhea, often with hematemesis and melena. Dehydration and thirst. 3. Muscle weakness, tremors, and rarely transient epileptiform convulsions, preceded or followed by progressive central nervous depression (lethargy, coma and respiratory arrest, even in the absence of circulatory failure).
-- LD50 ranges of sodium, potassium, or ammonium fluorosilicates administered intragastrically in rats and mice were 89-128 and 45-64 mg fluoride ion/kg, respectively. Severe cornea damage was observed 3 hr after the administration of 50 mg of any of the salts into rabbits' eyes. Min toxic dose (intragastric) of fluorosilicic acid in rats was 8 mg/kg. Min toxic concn in 4 hr inhalation of the salt aerosols were 7.4-9.6 mg/cu m; nontoxic concn was 0.8 mg/cu m. Main toxic effects were decreased activities of cholinesterase and lactat
e dehydrogenase in blood serum. The intragastric effects of the fluorosilicates were similar to and additive with those of sodium fluoride. [Rumyantser GI et al; Oig Sanit (11): 80-2 (1988)]
Ref: TOXNET profile from Hazardous Substances Data Bank for AMMONIUM SILICOFLUORIDE
http://www.fluoridealert.org/pesticides/Ammonium.Silicofluor.TOXNET.htm

Chronic: Causes severe skin irritation and burns. Ingestion or inhalation may be harmful and possibly fatal depending on severity and length of over-exposure. Chronic over- exposure may cause fluorosis. Product may be absorbed through the skin and produce signs of fluorosis such as weight loss, brittleness of bones, anemia, weakness and stiffness of joints. Internal bleeding may develop. First aid procedures should be followed even in cases of suspected contact.
Ref: Ammonium fluorosilicate Material Safety Data Sheet from LCI, Ltd.
http://www.fluorideaction.org/pesticides/ammonium.fluosilicate.msds.htm

Bone (click on for all fluorinated pesticides)

Chronic: Causes severe skin irritation and burns. Ingestion or inhalation may be harmful and possibly fatal depending on severity and length of over-exposure. Chronic over- exposure may cause fluorosis. Product may be absorbed through the skin and produce signs of fluorosis such as weight loss, brittleness of bones, anemia, weakness and stiffness of joints. Internal bleeding may develop. First aid procedures should be followed even in cases of suspected contact.
Ref: Ammonium fluorosilicate Material Safety Data Sheet from LCI, Ltd.
http://www.fluorideaction.org/pesticides/ammonium.fluosilicate.msds.htm

Tremors/Convulsions (click on for all fluorinated pesticides)

Human Toxicity Excerpts: SYMPTOMATOLOGY: A. Ingestion of soluble fluoride salts. 1. Salty or soapy taste, salivation, nausea. Repeated small doses (as in drinking water) may produce no other symptoms, but polyuria and polydipsia [def: excessive thirst] have also been reported. 2. Large doses lead promptly to burning or crampy abdominal pain, intense vomiting and diarrhea, often with hematemesis [ def: Vomiting of blood] and melena. Dehydration and thirst. 3. Muscle weakness, tremors, and rarely transient epileptiform convulsions, preceded or followed by progressive central nervous depression (lethargy, coma and respiratory arrest, even in the absence of circulatory failure).
Ref: TOXNET profile from Hazardous Substances Data Bank for AMMONIUM SILICOFLUORIDE
http://www.fluoridealert.org/pesticides/Ammonium.Silicofluor.TOXNET.htm

Environmental (click on for all fluorinated pesticides)

Fluoride/fluorinated substances identified in Agreement between Canada and the United States on Great Lakes Water Quality, 1978.
Appendix 1
Hazardous Polluting Substances: Ammonium Bifluoride * Ammonium Fluoborate * Ammonium Fluoride * Ammonium Silicofluoride * Antimony Trifluoride * Beryllium Fluoride * Ferric Fluoride * Hydrofluoric Acid * Lead Fluoborate * Lead Fluoride * Sodium Bifluoride * Sodium Fluoride * Zinc Fluoride * Zinc Silicofluoride * Zirconium Potassium Fluoride.
Appendix 2
Potential Hazardous Polluting Substances: Aluminum Fluoride * Antimony Pentafluoride * Benfluralin * Chlorflurazole * Cobaltous Fluoride * Stannous Fluoride

 
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