Adverse Effects:

Ataxia
Brain
CNS
Lung
Tremor/Convulsions

Environmental Effects:

Birds: High to Very high toxicity

Fish: Very highly toxic

112802
117601

Other Names:

EL-614
Assault mouse/rat place pak
Fastrac all-weather blox (bromethalin 0.01% by weight)
Fastrac mouse seed place pac
Green thumb mouse killer
Hot shot sudden death brand rat killer 1
New rampage rodenticide place pacs
Protecta
Purina assault meal
Talpirid mole bait (bromethalin 0.025% by weight)
Top gun pellet rodenticide
Vengence

Proposed Risk Mitigation Decision; Notice of Availability.
This notice announces the availability of EPA's proposed risk mitigation decision for nine rodenticides, the economic impact assessment for the proposed risk mitigation decision, the revised comparative ecological risk assessment, updated human health and ecological incident reports, and other related documents, and opens a 60-day public comment period on the proposed risk mitigation decision. The nine rodenticides covered by this risk mitigation decision are brodifacoum, bromadiolone, difethialone, chlorophacinone, diphacinone, warfarin, zinc phosphide, bromethalin, and cholecalciferol. Documents available:

Extension of Comment Period to January 21, 2005, re: Rodenticides; Availability of Revised Comparative Ecological Risk Assessment. Documents available are:
• Potential Risks of Nine Rodenticides to Birds and Nontarget Mammals: a Comparative Approach - July 2004 (230 pages)
• Update to the Overview of the Rodenticide Comparative Ecological Assessment - September 9, 2004 (4 pages)
• Analysis of Rodenticide Bait Use - September 10, 2004 (43 pages)
• EFED Response to USDA/APHIS’ “Partner Review Comments: Preliminary Analysis of Rodenticide Bait Use and Potential Risks of Nine Rodenticides to Birds and Nontarget Mammals: A Comparative Approach (June 9, 2004)” - September 7, 2004 (24 pages)
• Response to Public Comments on EFED's Risk Assessment: "Potential Risks of Nine Rodenticides to Birds and Nontarget Mammals: a Comparative Approach", dated December 19, 2002- July 17, 2004 (24 pages)
• "Potential Risks of Nine Rodenticides to Birds and Nontarget Mammals: A Comparative Approach"; revised document dated July 2004 - July 22, 2004 (2 pages)

Excerpts from Potential Risks of Nine Rodenticides to Birds and Nontarget Mammals: a Comparative Approach - July 2004 (230 pages)
-- Mammalian predators and scavengers are at risk from feeding on animals poisoned with anticoagulant baits. Although the non-anticoagulant rodenticides appear to be much less hazardous to secondary consumers, confirmatory data are still needed to make this assumption for bromethalin and cholecalciferol baits.

-- Bromethalin, a diphenylamine, is a neurotoxicant that causes respiratory arrest from inadequate nerve impulse transmission after fluid build-up and demyelination inside the central nervous system (Spaulding and Spannring 1988, Hyngstrom et al. 1994).

-- Risks to Nontarget mammals ... Too few data are available to adequately assess potential risks of either bromethalin or cholecalciferol (page 85).

-- Little information is available on methodology for detecting bromethalin or cholecalciferol in body tissues (page 90).

-- Lack of data for some rodenticides accounts for the most uncertainty in the comparative analysis model results. Data gaps include no secondary-hazards data for difethialone and few for bromethalin and cholecalciferol (page 105).

-- Two factors are identified as contributing the greatest uncertainty to the analysis: (1) missing data, especially secondary mortality data for difethialone, bromethalin, and cholecalciferol, and blood and liver retention values for a number of rodenticides; ... (page 149)