CAS Nos. 101007-06-1 and 103833-18-7

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Adverse Effects

ACTIVITY: Acaracide, Insecticide (pyrethroid). Wood Preservative (to control termites)

CAS Name: (S)-cyano(3-phenoxyphenyl)methyl [1R-[1a,3a(Z)]]-2,2-dimethyl-3-[3-oxo-3-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-1-propenyl]cyclopropanecarboxylate



Adverse Effects:

Body Weight Decrease
Endocrine: Thymus

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No
US EPA PC Code: 
US FDA LMS Code: A03
Registered use in
(includes only a limited list of countries) 
Japan, Portugal, South Africa, Vietnam
Japan's Maximum Residue Levels

Apple • Apricot • Cherry • Corn (including Maize, Sweet corn) • Cotton seeds • Cucumber (including Gherkin) • Eggplant • Grape • Grapefruit • Japanese pear • Japanese persimon • Japanese plum (including Prunes) • Kidney beans (with pods, immature) • Lemon • Lime • Loquat • MAKUWAURI • Melons • Mume plum • NATSUDAIDAI (whole) • Nectarine • Onion • Orange (including Navel) • Orinetal pickling melon (vegetable) • Other Citrus fruits • Other cucurbitaceous vegetables • Peach • Pear • Peas (with pods, immature) • Pimento (Sweet pepper) • Pumpkin (including Squash) • Quince • Soybeans (dry) • Strawberry • Tea • Tomato • UNSHU orange • Watermelon

-- Note high level - 10 ppm - for Tea (Green, Black, Oolong, Wulung)

Other Information
Molecular Formula: C26H21 F6 NO5
Entry Year: 1990
Manufacturers: Hoechst
Other Names: Rufast
RU 38702
NU 702
Hoe 076003
Of special interest:
PAN Data 
1998 - Summary of Toxicological Studies - Market Development, AgrEvo Japan Ltd. 
April 17, 2002 - Bayer's acquistion of Aventis. Discussion of the organfluorine pesticides: Acrinathrin, Beta-Cyfluthrin, Cyfluthrin, Ethiprole, Fipronil, Fluquinconazole. European Commission press release.
Oct 2001 - Glossary of Pesticide Chemicals - A listing of pesticides subject to analysis of residues in foods and feeds by the US Food and Drug Administration.
2000 - Food and Drug Administration Pesticide Residue Monitoring. April 2000. Table 3. Pesticides detectable by methods used in 1999 regulatory monitoring. 
Active substance of GABON PA 92 strips. Data Sheet. Produced at Bee Research Institute at Dol., Czech Republic. 
1992 - In Japan: Listed since Nov 19, 1992, as a Designated Chemical Substance. A substance which, either in itself or one of its degradation products, is not easily degradable or which may be harmful to human health when ingested continuously and which is considered to cause or expected to cause harm to human health due to significant residues of the substance in a wide range of areas. A person who manufactures or imports this substance shall for every fiscal year submit a report on manufactured or imported quantities. Division of Chem-Bio Informatics, National Institute of Health Sciences, Japan. 

Table D2: Details of Residues Exceeding non-harmonised MRLs,
including national MRLs

Surveillance sampling
Reporting country: Germany
Year of sampling: 2003
Pesticide Food item Point of sampling (*) Country of origin Residue in mg/kg national MRL (mg/kg) Follow-up (**) Sample reference
acrinathrin Peppers R ES 0.02 0.01 - 0001823079
acrinathrin Peppers O ES 0.03 0.01 A 0001841922
acrinathrin Peppers O ES 0.09 0.01 A 0001822544
acrinathrin Peppers R QU 0.03 0.01 - 0001823066
acrinathrin Strawberries O IT 0.05 0.01 A 0001421776
acrinathrin Strawberries R IT 0.07 0.01 - 0001566257
acrinathrin Strawberries O IT 0.09 0.01 A 0001421838
acrinathrin Strawberries R ES 0.03 0.01 - 0001566274
acrinathrin Strawberries O ES 0.06 0.01 A 0001421713
acrinathrin Table Grapes R GR 0.1 0.01 - 0001823042
acrinathrin Table Grapes O IT 0.013 0.01 - 0001829579
acrinathrin Table Grapes O IT 0.015 0.01 - 0001829580
acrinathrin Table Grapes O IT 0.016 0.01 - 0001829588
acrinathrin Table Grapes O IT 0.019 0.01 - 0001829587
acrinathrin Table Grapes R IT 0.02 0.01 - 0001823051
acrinathrin Table Grapes O IT 0.03 0.01 A 0001829573
acrinathrin Table Grapes O IT 0.032 0.01 A 0001821396
acrinathrin Table Grapes O IT 0.11 0.01 A 0001829571
acrinathrin Table Grapes O ES 0.042 0.01 A 0001829578

(*) Point of sampling in distribution: F = farmgate, R = retail, W = wholesale, O = other

(**) A: Administrative consequences have followed, e.g. prohibiting for sale, prosecutions, the levying of penalties or fines

These explanatory notes are cited at

June 14, 2001 - Implementation of the Community Strategy for Endocrine Disruptors - a range of substances suspected of interfering with the hormone systems of humans and wildlife. Communication from the Commission to the Council and the European Parliament. Commission of the European Communities, Brussels COM (2001) 262 final. (More information available at: )

This document presents a "priority list of substances for further evaluation of their role in endocrine disruption. During 2000, a candidate list of 553 man-made substances and 9 synthetic/natural hormones has been identified."

Synthetic pyrethroids While only the broad category "Synthetic pyrethroids" was included in the Commission's list, the following organofluorine pesticides are in this category: Acrinathrin, Bifenthrin, beta-Cyfluthrin, Cyhalothrin, gamma-Cyhalothrin, lambda-Cyhalothrin, Fenfluthrin, Flucythrinate, Flufenprox, Flumethrin, Fluvalinate, tau-Fluvalinate, Halfenprox, Protrifenbute, Silafluofen, Tefluthrin, Transfluthrin

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