Abstracts
Triflumuron
CAS No. 64628-44-0
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ACTIVITY: Insecticide (Benzoylurea)

CAS Name: 2-chloro-N-[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]benzamide

Structure:


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11432004&dopt=Abstract

Aust Vet J 2001 May;79(5):358-62

Surveys to assess the amount of pesticide in wool and the use of pesticides by woolgrowers in Queensland.

Ward MP, Armstrong RT.

Queensland Department of Primary Industries, Animal Research Institute, Locked Mail Bag 4, Moorooka, Queensland 4105.

OBJECTIVE: To measure the amounts of pesticide residue in wool grown in Queensland between 1997 and 1999, and to describe the use of pesticides for the control of lice infestations and blowfly strike in Queensland sheep flocks.
DESIGN: Pesticide residues were measured in a random sample of wool from Queensland clips offered for sale during 1998 and 1999. Information on pesticide use was obtained from a trace-back postal survey.
PROCEDURE: Samples taken from wool lots were tested for the presence and amount of organophosphorus (OP), synthetic pyrethroid (SP) and insect growth regulator pesticides. A questionnaire seeking information on flock characteristics and pesticide use was sent to the manager of each flock from which a wool sample was tested.
RESULTS: The mean amount of OP and SP residue was 2.0 and 0.8 mg/kg, respectively. Ninety-five and 98% of wool samples contained < 9 mg/kg and 7 mg/kg of OP and SP residues, respectively. The mean amount of cyromazine, diflubenzuron and triflumuron was 12.7, 5.8 and 13.0 mg/kg, respectively. The amounts of OP, cyromazine and triflumuron residues were greater in wool from flocks located in southern Queensland.
CONCLUSION: Most (95%; 95% CI, 92-97%) Queensland wool clips grown between 1997 and 1999 meet the suggested Australian maximum acceptable residue amounts for OP and SP pesticides.


PMID: 11432004 [PubMed - indexed for MEDLINE]


From: http://www.modares.ac.ir/mjms/p-e5.html

Modarres Journal of Medical Sciences Vol. 2, No.2, Winter 2000

A Laboratory and Field Evaluation of Triflumuron (S.C. 48%) as a tanricide on Malaria Vectors In the Natural Breeding Places In South of Iran

Farashiani *1 (M.Sc.), Ladonni H. 2 (Ph.D.) and Abdai M.R. 3 (M.Sc)

* Corresponding Address: Forest and Rangeland Research Institute, P.O.Box: 31585-343, Karaj, I.R.Iran.
1. M.Sc. Graduate, Department of Entomology, Trabiat Modarres University.

2. Associate Professor, Department of Medical Entomology, School of Public Health, and Institule of Public Health Sciences, Tehran University of Medical Sciences.
3. Researcher, Kazeroon Medical Research Center.

Malaria is one of the main parasitic diseases in south of Iran. Anopheles stephensi is known to be the main malaria vector in this area. The natural breeding places of this vector were different. Many of them had running water and other had standing water. The larvicidil activity of a new chitin synthesis inhibitor Crriflumnron, SC 48%) was studied in the laboratory and field conditions. In the laboratory studies, the efficacy of triflomuron on the third instar larvae of Anopheles stephensi was determined. These larvae were treated with triflumuron on diferent exposure times (0.5 ,1 ,2, 4, 6, 8, 12, 16, 24, 48 hour, and continued exposure time). The results indicated that with the increase of the exposure time, the mortality will gradually increase to about 75% up to the 24 hour and to about 90% up to the continued exposure times. The results revealed that larvicide would be present at a desired concentration (about 0.0008 mg/l) in the larval breeding place. Triflumuron was applied at 48 , 72 , 96 and 120 gr a.i/ha dosages. Triflumuron was effective on the larvae of anopheline mosqunes in the natural breeding place with standing water at 96 and 120 gr a.i/ha dosages. In the natural breeding place with running water, triflumuron was not effective at any dosages.


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J Agric Food Chem 1999 Jul;47(7):2926-9
 
Dissipation of teflubenzuron and triflumuron residues in field-sprayed and cold-stored pears.

Aplada-Sarlis PG, Miliadis GE, Tsiropoulos NG.

Department of Theoretical and Applied Sciences, University of Thessaly, Pedion Areos, Volos 38334, Greece.

Dissipation of residues of benzoylurea insecticides teflubenzuron (TFB) and triflumuron (TFM) under field conditions was evaluated on a pear orchard in Greece. Residues were determined by UV-HPLC analysis, with a detection limit of 0.030 mg/kg for both pesticides. TFB residues in pears were found to persist for 2 weeks and decline thereafter with 48% of the initial deposit remaining 42 days after the last application. TFM residues were found to decline following first-order kinetics and with a half-life of 39(+/-7) days. Residues of both pesticides found in pears collected at harvest maturity were lower than the maximum residue limits (MRLs) set by individual countries. Dissipation of TFB and TFM in cold-stored pears was also evaluated. TFB residues were very persistent for the whole storage period, whereas TFM residues did not dissipate for 6 weeks and then showed a constant decline; 7% of the initial concentration remained at the end of the storage period of 29 weeks.

PMID: 10552588 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10220916&dopt=Abstract

J Chromatogr A 1999 Mar 12;835(1-2):113-20

High-performance liquid chromatographic determination of benzoylurea insecticides residues in grapes and wine using liquid and solid-phase extraction.

Miliadis GE, Tsiropoulos NG, Aplada-Sarlis PG.

Benaki Phytopathological Institute, Kifissia, Greece.

A method for the determination of the benzoylurea insecticides diflubenzuron, triflumuron, teflubenzuron, lufenuron and flufenoxuron in grapes and wine by HPLC has been developed and validated. Grape samples (50 g) were homogenized and extracted with ethyl acetate-sodium sulfate and further cleaned-up by solid-phase extraction on silica sorbent. Wine samples (10 ml) diluted with water (1:3) were solid-phase extracted on an octadecyl sorbent using methanol as the eluent. The pesticides were separated on a reversed-phase octadecyl narrow-bore column by gradient elution and the residues were determined with a UV diode array detector. The calibration plots were linear over the range 0.05-5 micrograms/ml. Recoveries of benzoylurea pesticides from spiked grapes (0.02-2.0 mg/kg) and wine (0.01-0.2 mg/l) were 85.8-101.6% and 69.1-104.8%, respectively, and the limits of quantification for these insecticides were < 0.01 mg/kg for grapes and < 0.01 mg/l for wine. The method was applied to the determination of flufenoxuron and teflubenzuron residues in grapes from treated fields and in produced wine.

PMID: 10220916 [PubMed - indexed for MEDLINE]

• Note from FAN: all the pesticides cited are organofluorines


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9830572&dopt=Abstract

Aust Vet J 1998 Oct;76(10):698-9

Residues of insect growth regulators on Queensland wool.

Ward MP, Armstrong RT.

Queensland Department of Primary Industries, Animal Research Institute, Moorooka, Queensland.

PMID: 9830572 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9823064&dopt=Abstract

Vet Parasitol 1998 Nov 16;79(3):239-45

The poultry red mite Dermanyssus gallinae (De Geer, 1778): current situation and future prospects for control.

Chauve C.

Laboratory of Parasitology, Veterinary School of Lyon, Marcy L'Etoile, France.

The current importance of Dermanyssus gallinae, mainly in egg layer, in Europe is pointed out. The limits of conventional control methods are underlined (development of mite resistance--future insecticide legislation and animal welfare legislation). Alternative control methods such as feeding deterrents or biological control, are reviewed in the context of poultry pest management.

Publication Types:

  • Review
  • Review, Tutorial

PMID: 9823064 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9824828&dopt=Abstract

Med Vet Entomol 1998 Oct;12(4):430-7

Suppression of the blowfly Lucilia sericata using odour-baited triflumuron-impregnated targets.

Smith KE, Wall R.

School of Biological Sciences, University of Bristol, U.K.

Field trials were carried out in 1995 and 1996 on farms in the south-west of England to assess the extent to which odour-baited targets could be used to suppress populations of the ectoparasitic blowfly, Lucilia sericata, in sheep pastures. Targets were constructed from 41 x 41 cm squares of aluminium sheet, covered by white cloth which had been dipped in a mixture of sucrose solution (50% w/v) and the chitin synthesis inhibitor triflumuron (10% suspension concentrate). Each target was baited with approximately 300 g of liver and sodium sulphide solution (10%). Three matched sheep farms were used in the trials. In 1995, triflumuron-impregnated targets were placed around the periphery of sheep pastures at one of the farms in late June, at approximately one target per hectare. In 1996, triflumuron-impregnated targets were placed around the periphery of sheep pastures of a second of the farms in early May, at approximately five targets per hectare. Each year, five sticky targets, used to monitor the L. sericata populations, were also placed in fields at the experimental and the other two farms, which acted as controls. In 1995, the results provided some, although inconclusive, evidence that the triflumuron-impregnated targets had reduced the numbers of L. sericata relative to the populations on the two control farms. In 1996, however, the density of L. sericata on the experimental farm was reduced to almost zero and remained significantly lower than on two control farms throughout the period during which the triflumuron-impregnated targets remained in the field. The results are discussed in relation to the use of triflumuron-treated targets as a practical means of controlling L. sericata and sheep blowfly strike.

PMID: 9824828 [PubMed - indexed for MEDLINE]


From Toxline at Toxnet

ENVIRONMENTAL SCIENCE & TECHNOLOGY; 31 (9). 1997. 2445-2454.

Fluorinated organics in the biosphere.

KEY BD, HOWELL RD, CRIDDLE CS

Dep. Civil Environ. Eng., Mich. State Univ., East Lansing, MI 48824, USA.

BIOSIS COPYRIGHT: BIOL ABS. The use of organofluorine compounds has increased throughout this century, and they are now ubiquitous environmental contaminants. Although generally viewed as recalcitrant because of their lack of chemical reactivity, many fluorinated organics are biologically active. Several questions surround their distribution, fate, and effects. Of particular interest is the fate of perfluoroalkyl substituents, such as the trifluoromethyl group. Most evidence to date suggest that such groups resist defluorination, yet they can confer significant biological activity. Certain volatile fluorinated compounds can be oxidized in the troposphere yielding nonvolatile compounds, such as trifluoroacetic acid. In addition, certain nonvolatile fluorinated compounds can be transformed in the biosphere to volatile compounds. Research is needed to assess the fate and effects of nonvolatile fluorinated organics, the fluorinated impurities present in commercial formulations, and the transformation

CAS Registry Numbers:
137938-95-5 - na
112839-33-5 - chlorazifop [C14H11Cl2NO4]
112839-32-4 - chlorazifop [ C14H11Cl2NO4]
106917-52-6 - flusulfamide [C13H7Cl2F3N2O4S]
104040-78-0 - flazasulfuron [C13H12F3N5O5S]
102130-93-8 - 4-Fluorothreonine [ C4-H8-F-N-O3 ]
101463-69-8 - flufenoxuron [C21H11ClF6N2O3]
101007-06-1 - acrinathrin [C26H21F6NO5]
97886-45-8 - dithiopyr [C15H16F5NO2S2]
96525-23-4 - flurtamone [C18H14F3NO2]
90035-08-8 - flocoumafen [C33H25F3O4]
88485-37-4 - fluxofenim [C12H11ClF3NO3]
85758-71-0 - 1-Decanol, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heneicosafluoro- [ C10-H-F21-O ]
83164-33-4 - diflufenican [C19H11F5N2O2]
82657-04-3 - bifenthrin [C23H22ClF3O2]
81613-59-4 - flupropadine [C20H23F6N]

80164-94-9 - Methanone, phenyl((trifluoromethyl)phenyl)-, dichloro deriv. [ C14-H7-Cl2-F3-O ]
80020-41-3 - furyloxyfen [C17H13ClF3NO5]
79622-59-6 - fluazinam [C13H4Cl2F6N4O4]
79538-32-2 - tefluthrin [C17H14ClF7O2]
77501-63-4 - lactofen [C19H15ClF3NO7]
77501-60-1 - fluoroglycofen [C16H9ClF3NO7]
76674-21-0 - flutriafol [C16H13F2N3O]
72850-64-7 - flurazole [C12H7ClF3NO2S]
72178-02-0 - fomesafen [C15H10ClF3N2O6S]
71422-67-8 - chlorfluazuron [C20H9Cl3F5N3O3]

69806-34-4 - Haloxyfop
[C15H11ClF3NO4]
69335-91-7 - fluazifop [C15H12F3NO4]
68694-11-1 - Triflumizole [ C15-H15-Cl-F3-N3-O ]
68085-85-8 - cyhalothrin [C23H19ClF3NO3]
67485-29-4 - hydramethylnon [C25H24F6N4]
66332-96-5 - flutolanil [C17H16F3NO2]
64628-44-0 - triflumuron [C15H10ClF3N2O3]
63333-35-7 - bromethalin [C14H7Br3F3N3O4]
62924-70-3 - flumetralin [C16H12ClF4N3O4]
61213-25-0 - flurochloridone [C12H10Cl2F3NO]
59756-60-4 - fluridone [C19H14F3NO]

57041-67-5 - Desflurane [ C3-H2-F6-O ]
56425-91-3 - flurprimidol [C15H15F3N2O2]
55283-68-6 - ethalfluralin [C13H14F3N3O4]
53780-34-0 - mefluidide [C11H13F3N2O3S]
50594-66-6 - acifluorfen [C14H7ClF3NO5]
42874-03-3 - oxyfluorfen [C15H11ClF3NO4]

40856-07-3 - Difluoromethanesulphonic acid [ C-H2-F2-O3-S ]
37924-13-3 - perfluidone [C14H12F3NO4S2]
35367-38-5 - diflubenzuron [C14H9ClF2N2O2]
33245-39-5 - fluchloralin [C12H13ClF3N3O4]
31251-03-3 - fluotrimazole [C22H16F3N3]
29091-21-2 - prodiamine [C13H17F3N4O4]
29091-05-2 - dinitramine [C11H13F3N4O4]

28606-06-6 - na
28523-86-6 - Sevoflurane [ C4-H3-F7-O ]
27314-13-2 - norflurazon [C12H9ClF3N3O]
26675-46-7 - Isoflurane [ C3-H2-Cl-F5-O ]
26399-36-0 - profluralin [C14H16F3N3O4]
25366-23-8 - thiazafluron [C6H7F3N4OS]

24751-69-7 - Nucleocidin [ C10-H13-F-N6-O6-S ]
14477-72-6 - Acetic acid, trifluoro-, ion(1-) [ C2-F3-O2 ]
9002-84-0 - Polytetrafluoroethylene (Teflon) ( (C2-F4)mult- or (C2-F4)x-)
2837-89-0 - 1,1,1,2-Tetrafluoro-2-chloroethane (Freon 124) [ C2-H-Cl-F4 ]

2164-17-2 - fluometuron [C10H11F3N2O]
1861-40-1 - benfluralin [C13H16F3N3O4]
1827-97-0 - 2,2,2-Trifluoroethanesulfonic acid [ C2-H3-F3-O3-S ]
1763-23-1 - Perfluorooctane sulfonic acid [ C8-H-F17-O3-S ]
1717-00-6 - 1,1-Dichloro-1-fluoroethane [ C2-H3-Cl2-F ]

1582-09-8 - trifluralin [C13H16F3N3O4]
1493-13-6 - Trifluoromethanesulfonic acid [ C-H-F3-O3-S ]
811-97-2 - 1,1,1,2-Tetrafluoroethane (Norflurane) [ C2-H2-F4 ]
754-91-6 - Perfluorooctanesulfonamide [ C8-H2-F17-N-O2-S ]

640-19-7 - fluoroacetamide [C2H4FNO]
513-62-2 - Fluoroacetate [ C2-H2-F-O2 ]
453-13-4 - 1,3-Difluoro-2-propanol [ C3-H6-F2-O ]
420-46-2 - 1,1,1-Trifluoroethane [ C2-H3-F3 ]
406-90-6 - Fluroxene (Ethene, (2,2,2-trifluoroethoxy)-) [ C4-H5-F3-O ]

370-50-3 - flucofuron [C15H8Cl2F6N2O]
335-76-2 - Perfluorodecanoic acid [ C10-H-F19-O2 ]
335-67-1 - Perfluorooctanoic acid (PFOA) [ C8-H-F15-O2 ]
311-89-7 - Perfluorotributylamine [ C12-F27-N ]
306-83-2 - 2,2-Dichloro-1,1,1-trifluoroethane [Freon 123) [ C2-H-Cl2-F3 ]
151-67-7 - 2-Bromo-2-chloro-1,1,1-trifluoroethane (HALOTHANE) [ C2-H-Br-Cl-F3 ]
144-49-0 - Fluoroacetic acid [ C2-H3-F-O2 ]

116-14-3 - Tetrafluoroethylene [ C2-F4 ]
98-56-6 - 1-Chloro-4-(trifluoromethyl)benzene [ C7-H4-Cl-F3 ]
88-30-2 - TFM (3-Trifluoromethyl-4-nitrophenol)[ C7-H4-F3-N-O3 ]
79-38-9 - Chlorotrifluoroethylene [ C2-Cl-F3 ]
76-38-0 - Methoxyflurane [ C3-H4-Cl2-F2-O ]
76-15-3 - Chloropentafluoroethane (Freon 115 )[C2-Cl-F5 ]
76-14-2 - Dichlorotetrafluoroethane (Freon 114 )[ C2-Cl2-F4 ]
76-13-1 - 1,1,2-Trichloro-1,2,2-trifluoroethane (Freon 113 ) [C2-Cl3-F3 ]
76-05-1 - Trifluoroacetic acid [ C2-H-F3-O2]
75-71-8 - Dichlorodifluoromethane (Freon 12) [ C-Cl2-F2]

75-69-4 - Trichloromonofluoromethane ( Freon 11, 11A, 11B) [C-Cl3-F]
75-68-3 - 1-Chloro-1,1-difluoroethane (Freon 142, Freon 142b) [ C2-H3-Cl-F2]
75-45-6 - Chlorodifluoromethane (Freon 21) [ C-H-Cl-F2]

75-43-4 - Dichlorofluoromethane (Freon 21) [C-H-Cl2-F]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8834749&dopt=Abstract

Med Vet Entomol 1996 Jan;10(1):97-100

Autosterilization of the house fly, Musca domestica, using the chitin synthesis inhibitor triflumuron on sugar-baited targets.

Howard J, Wall R.

School of Biological Sciences, University of Bristol, U.K.

PMID: 8834749 [PubMed - indexed for MEDLINE]


From Toxline at Toxnet

HRC JOURNAL OF HIGH RESOLUTION CHROMATOGRAPHY; 19 (2). 1996. 105-110.

HPLC-UV DETERMINATION OF PESTICIDE RESIDUES AT 0.01 PPM IN APPLE AND PEAR PULP USED FOR BABY FOOD

BICCHI C, BALBO C, BINELLO A, D'AMATO A

Abstract: BIOL ABS. RRM RESEARCH ARTICLE FOOD TOXICITY DIFLUBENZURON ETHIOFENCARB TEFLUBENZURON TRIFLUMURON TRIFORINE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY ANALYTICAL METHOD

CAS Registry Numbers:
• 99039-56-2 - N-(((3,5-Dichloro-2,4-difluorophenyl)amino)carbonyl)-2,6-difluorobenzamide
64628-44-0 - Triflumuron
• 35367-38-5 - Diflubenzuron
29973-13-5 - Ethiofencarb (Croneton)
26644-46-2 - Triforine
• = fluorinated


From Toxline at Toxnet

KAOHSIUNG JOURNAL OF MEDICAL SCIENCES; 10 (SUPPL.). 1994. S102-S108.

DENGUE VECTOR CONTROL PRESENT STATUS AND FUTURE PROSPECTS

YAP HH, CHONG NL, FOO A ES, LEE CY

Abstract: BIOL ABS. RRM JOURNAL ARTICLE AEDES-AEGYPTI AEDES-ALBOPICTUS BACILLUS-THURINGIENSIS BACTERIAL LARVICIDE INSECTICIDES CHEMICAL CONTROL

CAS Registry Numbers:
95737-68-1 - Pyriproxyfen
64628-44-0 - Triflumuron
52645-53-1 - Permethrin
40596-69-8 - Methoprene
• 35367-38-5 - Diflubenzuron
3383-96-8 - Temefos
134-62-3 - Diethyltoluamide (Deet)
121-75-5 - Malathion
• = fluorinated


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8440876&dopt=Abstract

J Appl Toxicol 1993 Jan-Feb;13(1):67-8

Comparative study on the effects of five benzoylphenylurea insecticides on haematological parameters in rats.

Tasheva M, Hristeva V.

National Centre of Hygiene and Medical Ecology, Sofia, Bulgaria.

Five benzoylphenylurea insecticides were administered to male Wistar rats for 28 days at oral doses of 100 mg kg-1 each. Elevation of methaemoglobin was found only in the diflubenzuron- and triflumuron treated groups. The number of reticulocytes was increased in all of the treated groups.

PMID: 8440876 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1476468&dopt=Abstract

Ann Soc Belg Med Trop 1992 Sep;72(3):197-203

[Small-scale evaluation of the efficacy of growth-regulating insecticides on larvae of the Simulium damnosum complex (Diptera: Simuliidae)]

[Article in French]

Doannio JM, Dossou-Yovo J, Duval J, Hougard JM.

Institut Pierre Richet/O.C.C.G.E., Bouake, Cote d'Ivoire.

The efficacy of insect growth regulators was assessed in small scale tests on larvae of the Simulium damnosum complex (Diptera: Simuliidae) in the Ivory Coast. Three compounds [OMS 2015 (triflumuron), OMS 3009 (teflubenzuron), OMS 3013 (chlorfluazuron)] belong to the group of benzoylphenyl-urea substitutes; these IGR's are supposed to inhibit chitin synthesis. Two other compounds are Juvenile Hormone Analogs (JHA's) (OMS 3007 and OMS 3019). The last compound (OMS 3010) is a phenoxycarbamate. The first three compounds had a low efficacy on blackfly larvae, which is consistent with the literature data for another compound of this group: diflubenzuron. The other three compounds (OMS 3007, OMS 3010 and OMS 3019) were much more efficient, OMS 3010 and OMS 3019 showing high activity at low concentrations. These results would justify further studies on the effect of larval age and exposure parameters, and eventually full scale river tests.

PMID: 1476468 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2388230&dopt=Abstract

J Med Entomol 1990 Jul;27(4):551-5

Ovicidal activity of chitin synthesis inhibitors when fed to adult German cockroaches (Dictyoptera: Blattellidae).

DeMark JJ, Bennett GW.

Department of Entomology, Purdue University, West Lafayette, Indiana 47907.

Ovicidal activity was observed in four adult groups (virgin males; virgin females; newly gravid females; and inseminated, reproducing females) of the German cockroach, Blattella germanica (L.), fed the chitin synthesis inhibitors triflumuron, chlorfluazuron, hexafluron, and UC 84572 (structure not disclosed) at the LC50's and LC95's determined from fifth-stage nymphs. All compounds were active only when fed to reproducing females (including the feeding period in which the ootheca is developing). Hexafluron and triflumuron at the LC50 caused 100% inhibition of hatch in reproducing females. Chlorfluazuron and UC 84572 at the LC50 had similar ovicidal activity (45.8 and 50.0% hatch, respectively). Female German cockroaches fed the chitin synthesis inhibitors before mating and after the ootheca had protruded from the abdomen were not affected. Reproductive capabilities of males were not affected, and males did not effectively transfer the compounds to untreated females during mating.

PMID: 2388230 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2226070&dopt=Abstract

Exp Appl Acarol 1990 Aug;9(1-2):123-30

Effects of five insect growth regulators on laboratory populations of the North American house-dust mite, Dermatophagoides farinae.

Downing AS, Wright CG, Farrier MH.

Department of Entomology, North Carolina State University, Raleigh 27695-7613.

The potential of insect growth regulators (methoprene, hydroprene, fenoxycarb, diflubenzuron and triflumuron) to control populations of the North American house-dust mite Dermatophagoides farinae (Hughes) was assessed in laboratory bioassays. Methoprene was most effective at suppressing population growth, especially at concentrations of 1.0% (10,000 ppm) and 5.0% (5000 ppm) active ingredient. Hydroprene, structurally related to methoprene, also suppressed house-dust mite populations but not as consistently as methoprene. Fenoxycarb may be effective at controlling house-dust mites but at greater concentrations than were tested. Diflubenzuron and triflumuron, two chitin-synthesis inhibitors, failed to suppress mite numbers and may, in fact, stimulate reproduction in some cases. Almost all concentration of the insect growth regulators were shown to be ineffective when assayed 90 days after treatment.

PMID: 2226070 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2607029&dopt=Abstract

J Econ Entomol 1989 Dec;82(6):1633-7

Efficacy of chitin synthesis inhibitors on nymphal German cockroaches (Dictyoptera: Blattellidae).

DeMark JJ, Bennett GW.

Second- and fifth-instar Blattella germanica (L.), fed the chitin synthesis inhibitors triflumuron, chlorfluazuron, hexafluron, and UC 84572 (structure not disclosed) were examined for mortality and developmental abnormalities. All compounds were active against B. germanica (L.), with lower diet concentrations being required to kill second instars compared with fifth instars. Chlorfluazuron was significantly more active against second and fifth instars (LC50 = 0.000191 and 0.000363% AI, respectively for the second and fifth instars). UC 84572 also killed nymphs at extremely low concentrations (LC50 = 0.000508 and 0.000754% AI, respectively, for second and fifth instars). LC50's for hexafluron and triflumuron against fifth instars were more than 1,000 times higher than that for chlorfluazuron. Sensitive periods of exposure were determined by comparing effects when four different age classes of fifth instars (1-, 4-, 7-, and 10-d old) fed on the compounds for 3 d. Triflumuron was most effective when ingested during the first three age classes and hexafluron was most effective during the last three age classes. Chlorfluazuron and UC 84572 were most effective when ingested during the second age class (days 4-6). Adults surviving exposure during the fifth instar were often deformed and weak; they died at a greater rate than the controls. However, most surviving adults were able to reproduce normally.

PMID: 2607029 [PubMed
- indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2503072&dopt=Abstract

Bull Environ Contam Toxicol 1989 Jul;43(1):60-5

Hematological studies on white male rats exposed to some antimoulting compounds.

Berberian IG, Enan EE.

Central Agricultural Pesticides Laboratory, University of Alexandria, Egypt.

PMID: 2503072 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3216068&dopt=Abstract

J Econ Entomol 1988 Dec;81(6):1662-4

Mortality of eggs and larvae obtained from house flies (Diptera: Muscidae) exposed to triflumuron residues.

Knapp FW, Cilek JE.

PMID: 3216068 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2979938&dopt=Abstract

J Egypt Public Health Assoc 1988;63(3-4):181-98

Hepatotoxicity of some antimoulting compounds in white male mice.

Berberian IG, Enan EE, el-Sabaawi EA, el-Sheweni S.

PMID: 2979938 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2422789&dopt=Abstract

Toxicology 1986 Jun;39(3):307-15

Effects of chitin synthesis inhibitors on incorporation of nucleosides into DNA and RNA in a cell line from Manduca sexta (L).

Klitschka GE, Mayer RT, Droleskey RE, Norman JO, Chen AC.

Five putative chitin synthesis inhibitors (CSI) were tested to determine if they inhibited nucleoside incorporation into acid precipitable material in a cell line from Manduca sexta (L.). The results varied. Diflubenzuron (DFB) (100 micron) inhibited cytidine incorporation by 38%; EL-494 (100 micron) inhibited adenosine incorporation by 43%; Bay Sir 8514 (100 micron) inhibited uridine incorporation by 24%. Superdiflubenzuron (100 micron) was the worst inhibitor overall (18-22%) for the benzoylphenyl urea CSI. The triazine CSI, CGA 19255, was the best inhibitor tested with 60% inhibition for cytidine and 49% for adenosine incorporation into DNA and RNA. Examination of cells incubated with diflubenzuron by scanning electron microscopy revealed distinct external morphological changes. Transmission electron microscopy showed that crystalline structures accumulated in the cytoplasm of cells treated with DFB. The crystalline structures were assumed to be diflubenzuron and they persisted even after diflubenzuron was removed from the medium.

PMID: 2422789 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3971061&dopt=Abstract

Bull Environ Contam Toxicol 1985 Jan;34(1):68-74

Effects of a nonpersistent insecticide (Alsystin) on abundance patterns of breeding forest birds.

Yahner RH, Quinn JL, Grimm JW.

PMID: 3971061 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6483739&dopt=Abstract

Poult Sci 1984 Sep;63(9):1748-51

Feeding BAY Vi 7533 to hens.

Miller RW, Wong Y, Thomas OP.

BAY Vi7533 (2-chloro-N-[[[4-(trifluoromethoxy)phenyl] amino] carbonyl] benzamide) was fed to White Leghorn and Vedette Mini-broiler breeder hens at concentrations ranging from 0 to 25 ppm in the ration. Concentrations of 15 and 25 ppm resulted in greater than 95% mortality of house flies, Musca domestica L., seeded as larvae into the droppings. Concentration of 25 ppm reduced egg production in the White Leghorn but not in the Vedette Mini-broiler hens. At each concentration (except 5 ppm for Vedette Mini-broilers) residues of the compound were detected in the eggs. These residues, however, had no adverse effects on fertility or hatchability of the eggs.

PMID: 6483739 [PubMed - indexed for MEDLINE]



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