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Adverse
Effects
Abstracts
ACTIVITY:
Herbicide (Pyridine
carboxylic acid)
CAS Name:
methyl 2-(difluoromethyl)-5-(4,5-dihydro-2-thiazolyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate
Structure:
Adverse
Effects:
Amyloidosis
Blood
Body Weight Decrease
Bone
Cancer: Likely to be a Human Carcinogen
- THYROID, KIDNEY
Cholesterol
Endocrine: Pituitary (disruption
of the thyroid-pituitary hormonal feedback mechanism)
Endocrine: Suspected Disruptor
Endocrine: Thyroid
Eye
Kidney
Liver |
Environmental
Effects:
Very
Highly Toxic to nontarget terrestrial and aquatic plants,
algae and diatoms
Moderate
to High Toxicity to Martine Invertebrates
Persistent
in soil |
Regulatory
Information
(only comprehensive for the US) |
US
EPA Registered: |
Yes |
US
EPA PC Code: |
129100 |
California
Chemical Code |
3984 |
US
Tolerances: |
CFR
180.496 |
FDA
LMS Code: |
B12 |
European
Commission: |
Not
allowed to be used as an active ingredient after July 25,
2003. |
Registered
use in
(includes only a limited list of countries)
|
Australia,
US
|
US
Maximum Residue Levels permitted
in food commodities
|
Grapefruit, Orange |
Other
Information |
Molecular
Formula: |
C16H17
F5 N2O2S |
Entry
Year: |
1989 |
Inventing
Company: |
Monsanto |
Manufacturers: |
Rohm
& Haas |
Other
Names: |
Visor
RH-123652
Mandate
MON 13200
MON 13211
13211-A
13211-B
707-EUP-136
Thiazophyr
Visor |
Manufacture
site: |
US:
Rohm & Haas, Dayton,
Ohio 45418 |
Of
special interest: |
PAN
Data |
February
1997 - US EPA Fact
Sheet. |
November
26, 2002 -
European Commission: Thiazopyr
is one of 320 pesticides to
be withdrawn in July 2003. "Some
320 substances used in plant protection products (PPPs) Ð including
insecticides, fungicides and herbicides Ð are to be withdrawn
from the market by 25 July 2003 as part of the European Commission's
new approach to the evaluation of active substances in plant
protection products. This aims to improve safeguards to ensure
that all such products in use are safe for the environment and
human health. Users, wholesalers and retailers of plant protection
products will need to be aware of whether the products they
use or sell are likely to be withdrawn, so as to prevent them
being left with stocks of unusable material. Those concerned
should contact their national authority to check the authorisation
status for any particular product. The Regulation (n¡ 2076/2002
of 20 November 2002), with the list of the 320 substances, has
now been published in the Offical Journal. Ref: MIDDAY EXPRESS.
News from the Press and Communication Service's midday briefing. |
Abstracts |
August
2001 -
IR-4: New
Products/Transitional Solution List -This
list contains brief descriptions of numerous new pest control
materials that have been introduced over the last several years.
Additionally, it contains information on some "older"
crop protection chemicals that are believed to have room for
new uses. This List includes: Thiazopyr
|
October
2001 - Glossary
of Pesticide Chemicals. A listing
of pesticides subject to analysis of residues in foods and feeds
by the US Food and Drug Administration. |
April
2000 -
Food and Drug Administration
Pesticide Residue Monitoring. - Table
3. Pesticides detectable by methods used in 1999 regulatory
monitoring. |
June
14, 2001 - Implementation
of the Community Strategy for Endocrine Disruptors - a
range of substances suspected of interfering with the hormone
systems of humans and wildlife. Communication from the Commission
to the Council and the European Parliament. Commission of
the European Communities, Brussels COM (2001) 262 final. (More
information available at:
http://europa.eu.int/comm/environment/docum/01262_en.htm
)
This
document presents a "priority list of substances for
further evaluation of their role in endocrine disruption.
During 2000, a candidate list of 553 man-made substances and
9 synthetic/natural hormones has been identified."
Organofluorine
pesticides in this list include: |
Substances
included on the Endocrine Disruptor Liist |
CAS
No. |
Substances
included on the Endocrine Disruptor Liist |
CAS
No. |
Bifenthrin |
82657-04-3
|
Flutriafol |
76674-21-0 |
Cyhalothrin
(@Karate) |
91465-08-6 |
Fluvalinate |
69409-94-5 |
Diflubenzuron |
35367-38-5 |
Prodiamine |
29091-21-2 |
Epoxiconazole |
- |
Stannane,
tributylfluoro [Tributyltin fluoride] |
1983-10-4 |
Fipronil |
- |
Thiazopyr |
117718-60-2- |
Fluazifop-butyl |
69806-50-4
|
Trifluralin |
- |
US
Federal Register |
Date
Published |
Docket
Identification Number |
Details |
Aug
4, 1997 |
OPP-300523 |
Pesticides
Subject to Tolerance Reassessment. |
March
5, 1997 |
OPP-300455 |
ROHM
& HAAS - Pesticide
Tolerances.- FINAL RULE. This document establishes
tolerances for residues of the herbicide thiazopyr and its
metabolites in or on the raw agricultural commodities orange
and grapefruit at 0.05 ppm. In the Federal Register of October
21, 1993 (58 FR 54354), EPA issued a notice announcing the
filing of a pesticide tolerance petition by Monsanto. The
petition requested that 40 CFR part 180 be amended by adding
a regulation for tolerances for combined residues of the herbicide
thiazopyr and its metabolites in or on the raw agricultural
commodities: Citrus, whole fruit at 0.05 ppm; cotton seed
at 0.05 ppm and cotton forage at 0.2 ppm. In the Federal Register
of August 24, l994 (59 FR 43580) EPA issued a notice of an
amendment to the petition. The tolerances requested were changed
to residues of thiazopyr and its metabolites in or on citrus
whole fruit at 0.05 ppm, cotton seed at 0.05 ppm and cotton
forage at 0.2 ppm. Monsanto Co. requested the petition be
amended to read: tolerances of 0.05 ppm for orange, whole
fruit and 0.05 for grapefruit, whole fruit. |
April
2, 1997 |
na |
- MONSANTO
- Approval
of Pesticide Product Registrations:
- Thiazopyr
Technical Herbicide.
EPA Reg. No. 707-250
- Visor
2E Herbicide
to control annual grasses and broadleaf weeds in grapefruit
and oranges. EPA Reg. No. 707-251
- NOTE:
EPA issued a notice, published the FR of June 10, 1993 (58
FR 32533; FRL-4582-6), which announced that Monsanto had
submitted applications to register the pesticide products
MON 13211-A Citrus Herbicide and Thiazopyr Technical (MON
13200) (EPA File Symbols 524-UAG and 524-UAE) containing
the active ingredient Thiazopyr
|
Nov
22, 1996 |
PF-673 |
ROHM
& HAAS - Pesticide
Tolerance Petition for residues of the herbicide in or on
the raw agricultural commodity orange (whole fruit) and grapefruit
(whole fruit) at 0.05 ppm. |
Nov 13, 1996 |
na |
ROHM
& HAAS - Issuance
of Experimental Use Permit (707-EUP-136). This experimental
use permit allows the use of 565.0 pounds of the herbicide
on 800 acres of tree nuts and 660 acres of peanuts to evaluate
the preemergence control of various annual grasses and broadleaf
weeds. The program is authorized only in the States of California,
Georgia, New Mexico, Oregon, and Texas for the tree nut program
and in the States of Alabama, Georgia, North Carolina, Oklahoma,
Texas, and Virginia for the peanut program. The experimental
use permit is effective from July 25, 1996 to July 25, 1998. |
1993 |
na |
MONSANTO
- Request
for residues in or on citrus whole fruit at 0.05 ppm, cotton
seed at 0.05 pm, and cotton forage at 0.2 ppm. This was
announced by USDA. The Federal Register for 1993 is not online. |
Thiazopyr
product: VISOR
2E HERBICIDE |
US
EPA Registration No: |
707-
251-AA |
Status
as of August 2002: |
Active |
Ingredients
found: |
22.3% of
THIAZOPYR
77.7% of INERT INGREDIENTS |
Use: |
ALMOND
(3001) || APRICOT (5001) || CHERRY (5002) || CITRUS FRUITS (ALL
OR UNSPEC) (2000) || GRAPEFRUIT (2002) || GRAPES (ALL OR UNSPEC)
(1014) || GRAPES, WINE (29143) || NECTARINE (5003) || NUT CROPS,
NUT TREES (ALL OR UNSPEC) (3000) || ORANGE (ALL OR UNSPEC) (2006)
|| PEACH (5004) || PESTICIDE PRODUCTS FOR TANK MIXES (99003)
|| PISTACHIO (PISTACHE NUT) (3011) || PLUM (INCLUDES WILD PLUMS
FOR HUMAN CONSUMPTION) (5005) || PRUNE (5006) || WALNUT (ENGLISH
WALNUT, PERSIAN WALNUT) (3009) || WEEDS, ANNUAL BROADLEAF (TARGET
PEST) (29638) || WEEDS, BROADLEAF (UNSPECIFIED) (29637) || |
Company: |
ROHM
& HAAS COMPANY
PHILADELPHIA
PA 19106-2399 |
|