Picoxystrobin
CAS No. 117428-22-5
 
 

Return to Picoxystrobin Adverse Effects

ACTIVITY: Fungicide (strobin)

CAS Name: methyl (?E)-?-(methoxymethylene)-2-[[[6-(trifluoromethyl)-2-
pyridinyl]oxy]methyl]benzeneacetate

Structure:

Adverse Effects:

Body Weight Decrease
Bone
Endocrine: Testicular

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No
Registered use in
(includes only a limited list of countries)

Germany, UK 
UK Temporary MRL's

Applicable from: January 2002

Barley and oats: 0.2 p pm
Wheat: 0.05 ppm

Other Information
Molecular Formula: C18H16 F3 NO4 
Entry Year: 1998 
Manufacturers: Syngenta 
(originally Zeneca)
Other Names: Acanto
ZA 1963
 
Of special interest:
PAN Data 
July 2003 - Review report for the active substance picoxystrobin. Picoxystrobin SANCO/10196/2003-Final. 3 June 2003. Finalised in the [European Commission] Standing Committee on the Food Chain and Animal Health at its meeting on 4 July 2003 in view of the inclusion of picoxystrobin in Annex I of Directive 91/414/EEC/. 
On 31 May 2001 Syngenta announced the first registration worldwide of its new broad-spectrrum strobilurin fungicide, picoxystrobin. It has been granted registration in Germany for use on wheat, barley, oats and rye, and will be markete4d as Acanto ®. This is the first of a number of cereal fungicide registrations expected, largely in other European countries.
Regulatory News - http://www.researchinformation.co.uk/pest/2001/B104732A.PDF
April 2002 - Beer in the UK: 23 organofluorine pesticides approved for use on malting barley. Published by the British Beer and Pubs Association and Brewing Research International.   
January 17, 2002 - Concern of effect on earthworms. Minutes of UK Advisory Committee on Pesticides. 
January 2001 - Syngenta is seeking permission to open a 50m agrochemicals plant at Grangemouth in May to produce a new fungicide called picoxystrobin. http://www.ukbusinesspark.co.uk/syngenta.htm
August 2001 - IR-4 New Products/Transitional Solution List - This list contains brief descriptions of numerous new pest control materials that have been introduced over the last several years. Additionally, it contains information on some "older" crop protection chemicals that are believed to have room for new uses. This List includes: Picoxystrobin  
October 2001. Glossary of Pesticide Chemicals. A listing of pesticides subject to analysis of residues in foods and feeds by the US Food and Drug Administration. 
July 1999 - Acknowledgement of dossier submitted by Zeneca Agrochemicals in the Official Journal of the European Communities.

Toxicologically significant compounds:
Parent compound; 2-[6-(trifluoromethyl) pyridin-2-yloxymethyl]-benzoic acid (metabolite 8, soil); o-phthalic acid (metabolite 15, grain)
Ref:
July 2003 - Review report for the active substance picoxystrobin. Picoxystrobin SANCO/10196/2003-Final. 3 June 2003. Finalised in the [European Commission] Standing Committee on the Food Chain and Animal Health at its meeting on 4 July 2003 in view of the inclusion of picoxystrobin in Annex I of Directive 91/414/EEC/.
http://www.fluorideaction.org/pesticides/picoxystrobin.eu.june.2003.pdf

 
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