ACTIVITY:
Acaricide;
Insecticide (pyrethroid)
CAS Name:
1-[[2-[4-(bromodifluoromethoxy)phenyl]-2-methylpropoxy]methyl]-3-phenoxybenzene
Structure:
Note:
This pesticide contains both bromine and
fluorine; a combination
that has the potential to produce severe adverse effects - particularly
to the brain. |
Adverse
Effects:
Note
from FAN:
•
No toxicological data available. See above.
|
Regulatory
Information
(only comprehensive for the US) |
US
EPA Registered: |
No |
European
Commission: |
Not
allowed to be used as an active ingredient after July 25,
2003. |
Registered
use in
(includes only a limited list of countries)
|
China,
Japan, Taiwan, Vietnam
China:
Papayas: 0.5 ppm
Pears, 0.5 ppm
Tea, 5.0 ppm
Wax Apples, 1.0 ppm
Taiwan:
Pears, 0.5 ppm
Tea, 5.0 ppm
Wax apples, 1.0 ppm |
Japan's
Maximum Residue Levels (MRLs) |
Apple,
Grapefruit, Lemon, Lime, Natsudaidai (whole), Orange, Other
Citrus fruits, Tea, Unshu orange |
Other
Information |
Molecular
Formula: |
C24H23Br
F2 O3 |
Entry
Year: |
1994 |
Manufacturers: |
Mitsui
Toatsu Chem., Inc. |
Other
Names: |
Brofenprox
MTI-732
Sirbon 5 EC |
Of
special interest: |
PAN
Data |
November
26, 2002 -
European Commission: Halfenprox
(ala Brofenprox) is one of 320
pesticides to be withdrawn in July 2003. Some
320 substances used in plant protection products (PPPs) - including
insecticides, fungicides and herbicides - are to be withdrawn
from the market by 25 July 2003 as part of the European Commission's
new approach to the evaluation of active substances in plant
protection products. This aims to improve safeguards to ensure
that all such products in use are safe for the environment and
human health. Users, wholesalers and retailers of plant protection
products will need to be aware of whether the products they
use or sell are likely to be withdrawn, so as to prevent them
being left with stocks of unusable material. Those concerned
should contact their national authority to check the authorisation
status for any particular product. The Regulation (n¡ 2076/2002
of 20 November 2002), with the list of the 320 substances, has
now been published in the Offical Journal. Ref: MIDDAY EXPRESS.
News from the Press and Communication Service's midday briefing. |
Glossary
of Pesticide Chemicals, October 2001.
A listing of pesticides subject to analysis of residues in foods
and feeds by the US Food and Drug Administration. |
JOURNAL
OF PESTICIDE SCIENCE; 21 (3). 1996.
311-316.
Comparison
of acaricidal, insecticidal, and nerve activities of halfenprox
(MTI-732) and related compounds.
Authors:
NISHIMURA K, OKIMOTO H, UENO T, SHIRAISHI S, KODAKA K, TOMODA
K
BIOSIS
COPYRIGHT: BIOL ABS. The 2-(4-perhalomethoxyphenyl)-2-methylpropyl
3-phenoxybenzyl ethers related to etofenprox were prepared.
Their insecticidal potencies against common cutworms and
American cockroaches were close to the respective potency
of etofenprox. The acaricidal potency
of the CF2BrO derivative (halfenprox) against two-spotted
spider mites was about 200 times higher than etofenprox
(C2H5O derivative). Halfenprox and related compounds induced
repetitive discharges with a single electrical stimulus
in the excised central nerve cord of the American cockroach
as a class of conventional pyrethroids. These compounds
also induced the slow-lasting sodium tail-current upon step
repolarization of the crayfish axonal membrane. These nerve
effects may be the major mode of action for the in vivo
activities of this class of compounds. Hydrophobicity is
likely to play some role in the variations of acaricidal
potency.
|
AGROCHEMICALS
JAPAN; 0 (67). 1995. 16-17
ANNIVERSE
HALFENPROX MTI-732 SIRBON A NEW ACARICIDE
Authors:
TOMODA K-I.
Abstract:
BIOSIS COPYRIGHT: BIOL ABS. RRM JOURNAL ARTICLE PANONYCHUS-CITRI
TETRANYCHUS-URTICAE PHYSICAL PROPERTIES, CHEMICAL PROPERTIES,
TOXICOLOGICAL PROPERTIES, BIOLOGICAL PROPERTIES
|
June
14, 2001 - Implementation
of the Community Strategy for Endocrine Disruptors - a
range of substances suspected of interfering with the hormone
systems of humans and wildlife. Communication from the Commission
to the Council and the European Parliament. Commission of
the European Communities, Brussels COM (2001) 262 final. (More
information available at: http://europa.eu.int/comm/environment/docum/01262_en.htm
)
This
document presents a "priority list of substances for
further evaluation of their role in endocrine disruption.
During 2000, a candidate list of 553 man-made substances and
9 synthetic/natural hormones has been identified." |
Category
included on the Endocrine Disruptor Liist |
Synthetic
pyrethroids |
While
only the broad category "Synthetic pyrethroids" was
included in the Commission's list, it might be of some interest
to note that the following organofluorine pesticides are "Synthetic
pyrethroids:" Acrinathrin, Bifenthrin,
beta-Cyfluthrin, Cyhalothrin, gamma-Cyhalothrin, lambda-Cyhalothrin,
Fenfluthrin, Flucythrinate, Flufenprox, Flumethrin, Fluvalinate,
tau-Fluvalinate, Halfenprox,
Protrifenbute, Silafluofen, Tefluthrin, Transfluthrin |
|