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Adverse
Effects
ACTIVITY:
Herbicide
(sulfonylurea)
Systematic Name: Benzoic acid, 2-(((((4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)-3-methyl-,
methyl ester
Structure:
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| Date
Pubilshed |
Docket
Identification Number |
Details |
| June
12, 2002 |
OPP-2002-0082
|
IR-4
* and Dupont.
Pesticide Tolerance
for residues in or on Beet (sugar roots and tops) and Chicory
(roots) -- all at 0.05 ppm. FINAL RULE.
-- Chronic toxicity rodents
NOAEL = 2.44 mg/kg/day LOAEL = 30.6 mg/kg/day based on decreased
body weight and body weight gain, alteration in hematology (mainly
males) and increased incidences of interstitial
cell hyperplasia in testes.
-- Chronic toxicity dogs
NOAEL = 26.9 mg/kg/day LOAEL = 116.6 mg/kg/day based on increased
liver weight, alkaline phosphatase,
and hepatocellular hypertrophy.
-- Carcino-genicity rats
NOAEL = 2.44 mg/kg/day LOAEL = 30.6 mg/kg/day based on decreased
body weight and body weight gain, alteration in hematology
(mainly males) and increased incidences
of interstitial cell hyperplasia in the testes. (Possible)
evidence of carcinogenicity
-- Carcino-genicity mice NOAEL
= 14.6 mg/kg/day LOAEL = 349 mg/kg/day based on increased
liver weight and increased hepatic
cell tumors (adenomas and/or carcinomas combined. (Possible)
evidence of carcinogenicity.
-- Special studies: In vivo The purpose
of these studies was to and in vitro mechanic investigate the
mechanism of Leydig cell studies
tumor induction in the testes of male rats.
A dose-dependent decrease in aromatase enzyme activity was seen
in vitro, but was inconclusive
in vivo. |
| August
8, 2001 |
PF-1036 |
IR-4
* - Pesticide
Tolerance Petition for residues of triflusulfuron methyl in
or on the raw agricultural commodity chicory (root) at 0.05
ppm. Additional data may be needed before EPA rules on
the petition. This notice includes a summary of the petition
prepared by Dupont, E.I. du Pont Nemours and Company. Comments
due by September 7, 2001. |
| Dec
22, 1999 |
PF-899 |
Dupont
- Petition
to Establish a Tolerance for residues in or on the raw agricultural
commodity [beet, sugar, root and beet, sugar, top at 0.05
ppm. |
| August
4, 1997 |
OPP-300523 |
Pesticides
Subject to Tolerance Reassessment. |
| June
14, 1996 |
PP
PP 4F4278/R2239 |
Dupont
- Pesticide
Tolerance for beets.. - FINAL RULE. This document
establishes time-limited tolerances for residues of the herbicide
triflusulfuron methyl in or on the raw agricultural commodities
sugar beet tops and sugar beet roots at 0.05 ppm. Because
additional time is needed for the petitioner to submit additional
product chemistry data for an updated manufacturing process,
the Agency is granting the tolerances for sugar beet root
and top with a 3-year expiration date. |
| August
17, 1995 |
PF-629 |
Dupont
- Pesticide
Tolerance Petition for residues of the herbicide in or on
the raw agricultural commodities sugar beet roots and sugar
beet tops at 0.05 ppm. |
| August
16, 1995 |
na |
Dupont
- Issuance
of Experimental Use Permit 352-EUP-160. This experimental
use permit allows the use of 225 pounds of the herbicide on
6,000 acres of sugar beets to evaluate the control of various
weeds. The program is authorized only in the States of California,
Colorado, Idaho, Michigan, Minnesota, Montana, Nebraska, North
Dakota, Ohio, Oregon, Texas, and Wyoming. The experimental
use permit is effective from March 24, 1995 to September 30,
1997. |
| May
31, 1995 |
OPP-30387 |
Dupont
- Application
to Register Upbeet Herbicide. Active ingredient: Triflusulfuron
methyl at 50 percent. For selective postemergence control
of broadleaf and grass weeds in sugar beets. |
| May
31, 1995 |
na |
Dupont
- Establishment
of Temporary Tolerances for residues of the herbicide triflusulfuron
methyl in or on the raw agricultural commodities sugar beet
roots and tops at 0.05 ppm. These temporary tolerances
will permit the marketing of the above raw agricultural commodities
when treated in accordance with the provisions of the experimental
use permit 352-EUP-160, which is being issued under the Federal
Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended
(Pub. L. 95-396, 92 Stat. 819; 7 U.S.C. 136). |
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*
Interregional Research Project #4 (IR-4),
681 US Highway #1 South, North Brunswick, NJ 08902 |
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