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Adverse Effects
Abstracts
US
Food Tolerances
ACTIVITY:
Herbicide (pyridazinone)
Note:
Two breakdown products: Demethylnorflurazon
(CAS No. 112748-69-3) and Desmethylnorflurazon
(CAS No. 23576-24-1)
CAS Name:
4-chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]-3(2H)-pyridazinone
Structure:
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| Published
Date |
Docket
Identification Number |
Details |
| Feb
10, 2005 |
OPP-2005-0025 |
Removal
of Expired Time-limited Tolerances for Emergency Exemptions.
FINAL
RULE.
• 14. Norflurazon. Time-limited
tolerances for Bermuda grass hay and forage
are being removed from Sec. 180.356 because they expired
on November 30, 2002. |
| July
30, 2003 |
OPP-2002-0327 |
US
EPA's Pesticide Reregistration Performance Measures and Goals.
Norflurazon
was one of 21 TREDS
(Tolerance Reassessment Progress and Interim
Risk Management Decisions) completed by US EPA in Fiscal
Year 2002.
• EPA issues Reports on FFDCA Tolerance Reassessment Progress
and Interim Risk Management Decisions, known as TREDs, for pesticides
that require tolerance reassessment decisions under FFDCA, but
do not require a reregistration eligibility decision at present
because:
• The pesticide was first registered after November 1984
and is considered a ``new'' active ingredient, not subject to
reregistration (e.g., fenarimol and primisulfuron-methyl in
FY 2002);
• EPA completed a RED for the pesticide before FQPA was
enacted (most FY 2002 TREDs are in this post-RED category);
or
• The pesticide is not registered for use in the U.S.
but tolerances are established that allow crops treated with
the pesticide to be imported from other countries (e.g., mevinphos).
... As with IREDs, EPA will not take final action on pesticides
subject to TREDs that are part of a cumulative group until cumulative
risks have been considered for the group. |
| Sept
13, 2002 |
OPP-2002-
0121 |
EPA
status of reregistration and tolerance reassessment. |
| June
11, 2002 |
OPP-2002-0096 |
Notice
of availabilty of TRED document (Tolerance Reassessment
Progress and Risk Management Decision).
... EPA did not perform a cumulative risk assessment as part
of this reregistration review of norflurazon, because the Agency
has not determined if there are any other chemical substances
that have a mechanism of toxicity common with that of norflurazon.
If EPA identifies other substances that share a common mechanism
of toxicity with norflurazon, then a cumulative risk assessment
will be conducted that includes norflurazon once the final framework
EPA will use for conducting cumulative risk assessments is available.
Further, EPA is in the process of developing criteria for characterizing
and testing endocrine disrupting chemicals and plans to implement
an Endocrine Disruptor Screening Program. Norflurazon will be
reevaluated at that time and additional studies may be required.
|
| Jan
30, 2002 |
OPP-181083 |
Request
for Emergency Exemption from the Alabama Department of Agriculture
and Industries. Proposal to make no more than one application
of norflurazon manufactured by Syngenta Crop Protection, Inc.
as Zorial Rapid 80, EPA Reg. No. 100-848, at a rate of 0.5 -
1.2 lb active ingredient/Acre (.6 - 1.5 lb product/Acre) by
ground to 60,000 acres of bermuda grass meadows between February
1 and July 31, 2002. |
| Nov
14, 2001 |
OPP-181082 |
- Pesticide
Emergency Exemptions. EPA authorized use in:
- Alabama:
on bermudagrass to control annual grassy weeds; March 6,
2001 to July 31, 2001.
- Georgia:
on bermudagrass to control annual grassy weeds; March 6,
2001 to July 1, 2001.
|
| Dec
20, 2000 |
OPP-181078 |
|
| Oct
19, 2000 |
OPP-301066 |
Extension
of Tolerances for Emergency Exemptions. - FINAL RULE.
This regulation extends time-limited tolerances
for combined residues of the herbicide norflurazon and
its desmethl metabolite in or on bermudagrass forage and hay
at 2 and 3 ppm respectively, for an additional 2-year period.
These tolerances will expire and are revoked on November 30,
2002. |
| Dec
27, 1999 |
OPP-66273 |
NOVARTIS
- Request
to voluntarily cancel two pesticide registrations for Solicam
DF Herbicide. EPA Registration Numbers: OR-90-0024 and
WA-90-0032. |
| March
24, 1999 |
OPP-300803 |
Extension
of Tolerance for Emergency Exemptions. - FINAL RULE.
This regulation extends a time-limited tolerance for the combined
residues of the herbicide norflurazon and its desmethyl metabolites
in or on bermudagrass forage and hay at 2 and 3 ppm respectively,
for an additional 1-year period. This tolerance will expire
and is revoked on November 30, 2000. |
| Feb
25, 1998 |
OPP-300615 |
Extension
of Tolerances for Emergency Exemptions.- FINAL RULE.
This rule extends time-limited tolerances for residues of the
herbicide norflurazon and its desmethyl metabolite in or on
bermudagrass forage and hay at 2 and 3 parts per million (ppm),
respectively, for an additional 1-year period, to November 30,
1999. |
| Feb
11, 1998 |
NA |
NOVARTIS
- Request
to Voluntarily Cancel Pesticide Registration: Boundary
DF Herbicide. EPA Reg. No. 000100-00873. |
| August
4, 1997 |
OPP-300523 |
Pesticides
Subject to Tolerance Reassessment. |
| June
13, 1997 |
NA |
- Emergency
Exemptions:
- Alabama
Department of Agriculture and Industries on March 28, 1997,
for the use of norflurazon on bermudagrass hay meadows to
control weeds. The need for this program is expected to
last until September 15, 1997.
- Louisiana
Department of Agriculture and Forestry on March 7, 1997,
for the use of norflurazon on bermudagrass to control grassy
weeds. The need for this program is expected to last until
September 15, 1997.
|
| May
9, 1997 |
NA |
- Emergency
Exemptions.
- Georgia
Department of Agriculture on February 28, 1997, for the
use of norflurazon on bermudagrass to control weeds. This
program is expected to last until July 1, 1997.
- Texas
Department of Agriculture on February 17, 1997, for the
use of norflurazon on bermudagrass to control weeds. This
program has ended.
|
| April
11, 1997 |
OPP-300470 |
Pesticide
Tolerance for Emergency Exemptions. - FINAL RULE.
This regulation establishes time-limited tolerances for residues
of the herbicide norflurazon in or on the raw agricultural commodities
bermudagrass hay and forage in connection with EPA's granting
of emergency exemptions under section 18 of the Federal Insecticide,
Fungicide, and Rodenticide Act authorizing use of norflurazon
on bermudagrass in the states of Alabama, Georgia, Louisiana,
Mississippi, and Texas. This regulation establishes maximum
permissible levels for residues of norflurazon in these foods
pursuant to section 408(l)(6) of the Federal Food, Drug, and
Cosmetic Act, as amended by the Food Quality Protection Act
of 1996. The tolerances will expire and be revoked by EPA on
November 30, 1998. |
| Oct
30, 1996 |
NA |
Emergency
Exemptions. EPA has granted specific exemption to the Mississippi
Department of Agriculture and Commerce for the use of norflurazon
on Bermudagrass to control weeds; June 12, 1996, to September
15, 1996. |
| Sept
26, 1996 |
NA |
Withdrawal
of Proposed Revocations of Pesticide Tolerances. |
| July
29, 1996 |
PP
9F3766/R2254 |
SANDOZ
- Pesticide
Tolerances.- FINAL RULE. This rule establishes
tolerances for residues of the herbicide norflurazon and its
desmethyl metabolite in or on the following raw agricultural
commodities: ALFALFA: forage at 3 ppm; hay at 5 ppm; seed
at 0.1 ppm. In or on meat by products (except liver) of cattle,
goats, hogs, horses, and sheep and in or on liver of cattle,
goats, hogs, horses and sheep at 0.01 ppm resulting from the
use of norflurazon in the culture of alfalfa. |
|
June 14, 1996 |
PF-654 |
SANDOZ
- Pesticide
Tolerance Petition; to establish tolerances for combined
residues of the herbicide norflurazon and its desmethyl metabolite
in or on the following raw agricultural commodities: alfalfa,
forage at 3.0 ppm, alfalfa, seed at 0.1 ppm, alfalfa, hay
at 5.0 ppm; cattle, goats, hogs, horses, and sheep, meat by
products, (except liver) at 0.1 ppm; cattle, goats, hogs,
horses, and sheep liver at 0.25 ppm. |
| May
15, 1996 |
OPP-34093 |
EPA's
Reregistration Eligibility Decision (RED) Development Schedule. |
| April
24, 1996 |
NA |
- Emergency
Exemptions. EPA has granted specific exemptions for the
use of norflurazon to control annual weeds to:
- Alabama
Department of Agriculture and Industries; February 1, 1996,
to July 1, 1996.
- Georgia
Department
of Agriculture; February 1, 1996, to July 1, 1996.
- Louisiana
Department of Agriculture and Forestry; February 23, 1996,
to April 15, 1996.
- Texas
Department of Agriculture; February 1, 1996, to June 15,
1996.
|
| March
1, 1996 |
OPP-300415 |
Proposed
Retention of Pesticide Tolerances. |
| Feb
7, 1996 |
OPP-180988 |
Request
for Emergency Exemption. EPA has received a specific exemption
request from the Georgia Department
of Agriculture for use of the pesticide, norflurazon, to control
grasses on up to 150,000 acres of Bermudagrass in Georgia. |
| Feb
1, 1996 |
PF-643 |
SANDOZ
- Pesticide
Petition for permanent tolerances for the combined residues
of the herbicide and its desmethyl metabolite [4-chloro-5-
(amino)-2-(alpha, alpha, alpha-trifluro-m-tolyl)-3(2H)-pyridazinone]
in or on bermudagrass forage at 3.0 ppm and bermudagrass hay
at 2.0 ppm. |
| Sept
21, 1995 |
OPP-300397 |
Pesticide
Tolerances; Feed Additive Regulations. Proposed Rule. |
| Sept
20, 1995 |
NA |
Emergency
Exemptions. EPA has granted specific exemption to the Louisiana
Department of Agriculture and Forestry for the use of norflurazon
on Bermudagrass to control annual grassy weeds; May 1, 1995,
to June 15, 1995. Louisiana had initiated a crisis exemption
for this use.
|
| August
30, 1995 |
PP
4E4383/P627 |
IR-4*
- Pesticide
Tolerance. Proposed Rule. EPA proposes to establish a
tolerance for combined residues of the herbicide norflurazon
and its desmethyl metabolite in or on the raw agricultural
commodity caneberries at 0.2 ppm. |
| April
26, 1995 |
NA |
- Emergency
Exemptions. EPA has granted specific exemptions to use norflurazon
on Bermuda grass to control annual grassy weeds:
- Alabama
Department of Agriculture and Industries; February 2, 1995,
to June 15, 1995.
- Georgia
Department of Agriculture; February 2, 1995, to July 1,
1995.
- Louisiana
Department of Agriculture and Forestry on February 13, 1995.
This program has ended.
- Texas
Department of Agriculture; February 2, 1995, to July 1,
1995.
|
| Jan
12, 1994 |
OPPTS-400082 |
EPA's
proposal to add 41
fluorine and organofluorine chemicals to the Toxics Release
Inventory (TRI). See excerpt in box
above. Also available at http://www.epa.gov/tri/frnotices/59fr1788.htm |
| *
Interregional Research Project No. 4 (IR-4) |
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