Flumetralin
CAS No. 62924-70-3
 
 

Return to Flumetralin Adverse Effects

ACTIVITY: Plant growth regulator (2,6-Dinitroaniline)

CAS Name: 2-chloro-N-[2,6-dinitro-4-(trifluoromethyl)phenyl]-N-ethyl-6-fluorobenzenemethanamine

Structure:

Environmental Effects:

Acute aquatic toxicity

Regulatory Information
(only comprehensive for the US)
US EPA Registered: Yes 
US EPA PC Code: 123001 
California Chemical Code 5085 
FDA LMS Code: 834 
US EPA Permit Date
and Registrant:
1983, Ciba Geigy 
European Commission:

Not allowed to be used as an active ingredient after July 25, 2003.

Registered use in
(includes only a limited list of countries)

US 
US approved use
Tobacco plants 
Other Information
Molecular Formula: C16H12Cl F4 N3O4  
Entry Year: 1977 
Inventing Company: Ciba Geigy 
Manufacturers: Novartis/Rhone Poulenc, Drexel, Syngenta  
Other Names: 

CGA 41065
Premier
Prime

BENZENEMETHANAMINE, 2-CHLORO-N-(2,6-DINITRO-4-(TRIFLUOROMETHYL)PHENYL)-N-ETHYL-6-FLUORO-

CHLORO-N-(2,6-DINITRO-4-(TRIFLUOROMETHYL)PHENYL)-N-ETHYL-6-FLUOROBENZENEMETHANAMINE

Of special interest:
PAN Data 
2005 - Schedule for Reregistration & Tolerance Reassessment (RED) is expected to be December 2007. Contact at EPA: Diane Isbell (703) 308-8154; isbell.diane@epa.gov . According to EPA:
Through the pesticide reregistration and tolerance reassessment programs, EPA is assessing risks and making risk management decisions for older pesticides. These decisions are summarized in documents known as REDs, IREDs, and TREDs. By making decisions according to the schedule below, EPA will meet its statutory deadlines for completing reregistration and tolerance reassessment.
Some of the decision dates presented in the schedule may change due to the dynamic nature of the review process. Any pesticide decisions that are not completed during the current fiscal year will be rescheduled for the following year. EPA is committed to meeting its reregistration and tolerance reassessment deadlines.
http://www.epa.gov/pesticides/reregistration/decision_schedule.htm
November 26, 2002 - European Commission: Flumetralin is one of 320 pesticides to be withdrawn in July 2003." Some 320 substances used in plant protection products (PPPs) – including insecticides, fungicides and herbicides – are to be withdrawn from the market by 25 July 2003 as part of the European Commission’s new approach to the evaluation of active substances in plant protection products. This aims to improve safeguards to ensure that all such products in use are safe for the environment and human health. Users, wholesalers and retailers of plant protection products will need to be aware of whether the products they use or sell are likely to be withdrawn, so as to prevent them being left with stocks of unusable material. Those concerned should contact their national authority to check the authorisation status for any particular product. The Regulation (n° 2076/2002 of 20 November 2002), with the list of the 320 substances, has now been published in the Offical Journal. Ref: MIDDAY EXPRESS. News from the Press and Communication Service's midday briefing. 
1995 - Data on "Prime" containing Flumetralin as the active ingredient. It is used as a plant growth regulator on Tobacco plants. Virginia Department of Health DIVISION OF HEALTH HAZARDS CONTROL 
1981 - 1998 - US EPA Index of Cleared Science Reviews.  
Glossary of Pesticide Chemicals, October 2001. A listing of pesticides subject to analysis of residues in foods and feeds by the US Food and Drug Administration.  

Rationale for US EPA to add Flumetralin to the Toxic Release Inventory

Flumetralin (2-chloro-N-(2,6-dinitro-4-(trifluoromethyl)- phenyl)-N-ethyl-6-fluorobenzenemethanamine). Aquatic acute toxicity values for flumetralin include a daphnid 48-hour EC 50 of greater than 2.8 ppb, a bluegill sunfish 96-hour LC 50 of greater than 3.2 ppb, and a rainbow trout 96-hour LC 50 of greater than 3.2 ppb. EPA believes that there is sufficient evidence for listing flumetralin on EPCRA section 313 pursuant to EPCRA section 313(d)(2)(C) based on the available environmental toxicity data for this chemical.

Ref: USEPA/OPP. Support Document for the Addition of Chemicals from Federal Insecticide, Fungicide, Rodenticide Act (FIFRA) Active Ingredients to EPCRA Section 313. U. S. Environmental Protection Agency, Washington, DC (1993).
As cited by US EPA in:
Federal Register: January 12, 1994. Part IV. 40 CFR Part 372. Addition of Certain Chemicals; Toxic Chemical Release Reporting; Community Right-to-Know; Proposed Rule.

Note:
Addition of Certain Chemicals; Toxic Chemical Release Reporting; Community Right-to-Know. Final Rule.
Flumetralin was included in the deferral of 40 chemicals: EPA is deferring final action on 40 chemicals and one chemical category until a later date. These chemicals and the comments received on them raised particularly difficult technical or policy issues which will require additional time to address. The Agency does not believe that it would be in the spirit of community right-to-know to delay final action on the remaining 286 chemicals and chemical categories, pending completion of work on the more limited group. In a future rulemaking, EPA will make a final determination as to whether these chemicals should be added to EPCRA section 313. The public comment that has been received specific to these deferred chemicals will be addressed as part of the future rulemaking discussed above.


US Federal Register
Date Published Docket Identification Number Details
May 15, 1996 OPP-34093' EPA's Reregistration Eligibility Decision (RED) Development Schedule. Note: As of October 29, 2001, EPA has not yet published. See: US EPA Red Status website
November 30, 1994 OPPTS-400082B7

Addition of Certain Chemicals; Toxic Chemical Release Reporting; Community Right-to-Know. Final Rule.

EPA is deferring final action on 40 chemicals and one chemical
category until a later date. These chemicals and the comments received
on them raised particularly difficult technical or policy issues which
will require additional time to address. The Agency does not believe
that it would be in the spirit of community right-to-know to delay
final action on the remaining 286 chemicals and chemical categories,
pending completion of work on the more limited group. In a future
rulemaking, EPA will make a final determination as to whether these
chemicals should be added to EPCRA section 313. The public comment that
has been received specific to these deferred chemicals will be
addressed as part of the future rulemaking discussed above. These
chemicals follow:
flumetralin

Jan 12, 1994 OPPTS-400082 EPA's proposal to add 41 fluorine and organofluorine chemicals to the Toxics Release Inventory (TRI). See excerpt in box above. Also available at http://www.epa.gov/tri/frnotices/59fr1788.htm
 
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