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ACTIVITY:
Insecticide (unclassified)
CAS Name:
N2-[1,1-dimethyl-2-(methylsulfonyl)ethyl]-3-iodo-N1-[2-methyl-4-[1,2,2,2-tetrafluoro-1-
(trifluoromethyl)ethyl]phenyl]-1,2-benzenedicarboxamide
Structure:
Adverse
Effects:
Endocrine: Testicular
Endocrine:
Thymus
Endocrine:
Thyroid
Endocrine:
Uterine
Eye
Liver
Reproductive / Developmental:
Spleen
Note:
Very little detailed data available as this is a new pesticide,
announced in October 2004. |
Endocrine:
Testicular (click
on for all fluorinated pesticides)
Results
of a reproductive toxicity study in rats (exposure route not stated):
Decreased sperm head count per testis in F1 parental males
Ref: TSCA Health & Safety Study
Cover Sheet "Public Display Copy"
http://www.epa.gov/opptintr/tsca8e/doc/8ehq/2004/november04/8ehq-1004-15768a.pdf
••
This
document was cited at EPA's
site: "TSCA 8(e) and FYI Submissions Received from 11-15-04-11-26-04".
It is important to note this as the document itself does not identify
flubendiamide or its CAS No.
•• This
study was conducted in the laboratory of The Institute of Environmental
Toxicology - Japan
•• Source of Data/Study
Sponsor: Bayer Material Science Corporation, 100 Bayer Road, Pittsburg
PA 15205
Endocrine:
Thymus (click
on for all fluorinated pesticides)
Results
of a reproductive toxicity study in rats (exposure route not stated):
Thyroid, liver, uterine, thymus,
and spleen weight changes in 2000
and 20000 ppm F1 and F2 pups.
Ref: TSCA Health & Safety Study Cover Sheet "Public Display
Copy"
http://www.epa.gov/opptintr/tsca8e/doc/8ehq/2004/november04/8ehq-1004-15768a.pdf
••
This
document was cited at EPA's
site: "TSCA 8(e) and FYI Submissions Received from 11-15-04-11-26-04".
It is important to note this as the document itself does not identify
flubendiamide or its CAS No.
•• This
study was conducted in the laboratory of The Institute of Environmental
Toxicology - Japan
•• Source of Data/Study
Sponsor: Bayer Material Science Corporation, 100 Bayer Road, Pittsburg
PA 15205
Endocrine:
Thyroid (click
on for all fluorinated pesticides)
Results
of a reproductive toxicity study in rats (exposure route not stated):
Thyroid, liver, uterine, thymus,
and spleen weight changes in 2000
and 20000 ppm F1 and F2 pups.
Ref: TSCA Health & Safety Study
Cover Sheet "Public Display Copy"
http://www.epa.gov/opptintr/tsca8e/doc/8ehq/2004/november04/8ehq-1004-15768a.pdf
••
This
document was cited at EPA's
site: "TSCA 8(e) and FYI Submissions Received from 11-15-04-11-26-04".
It is important to note this as the document itself does not identify
flubendiamide or its CAS No.
•• This
study was conducted in the laboratory of The Institute of Environmental
Toxicology - Japan
•• Source of Data/Study
Sponsor: Bayer Material Science Corporation, 100 Bayer Road, Pittsburg
PA 15205
Endocrine:
Uterine (click
on for all fluorinated pesticides)
Results
of a reproductive toxicity study in rats (exposure route not stated):
Thyroid, liver, uterine, thymus,
and spleen weight changes in 2000
and 20000 ppm F1 and F2 pups.
Ref: TSCA Health & Safety Study
Cover Sheet "Public Display Copy"
http://www.epa.gov/opptintr/tsca8e/doc/8ehq/2004/november04/8ehq-1004-15768a.pdf
••
This
document was cited at EPA's
site: "TSCA 8(e) and FYI Submissions Received from 11-15-04-11-26-04".
It is important to note this as the document itself does not identify
flubendiamide or its CAS No.
•• This
study was conducted in the laboratory of The Institute of Environmental
Toxicology - Japan
•• Source of Data/Study
Sponsor: Bayer Material Science Corporation, 100 Bayer Road, Pittsburg
PA 15205
Eye
(click
on for all fluorinated pesticides)
Results
of a reproductive toxicity study in rats (exposure route not stated):
Increased incidence of eyeball enlargement
and dark-colored liver in 2000 and 20000
ppm F1 and F2 pups.
Ref: TSCA Health & Safety
Study Cover Sheet "Public Display Copy"
http://www.epa.gov/opptintr/tsca8e/doc/8ehq/2004/november04/8ehq-1004-15768a.pdf
••
This
document was cited at EPA's
site: "TSCA 8(e) and FYI Submissions Received from 11-15-04-11-26-04".
It is important to note this as the document itself does not identify
flubendiamide or its CAS No.
•• This
study was conducted in the laboratory of The Institute of Environmental
Toxicology - Japan
•• Source of Data/Study
Sponsor: Bayer Material Science Corporation, 100 Bayer Road, Pittsburg
PA 15205
Liver
(click
on for all fluorinated pesticides)
Results
of a reproductive toxicity study in rats (exposure route not stated):
• Increased incidence of eyeball enlargement and dark-colored
liver in 2000 and 20000 ppm F1 and F2 pups.
•
Thyroid, liver, uterine, thymus,
and spleen weight changes in 2000
and 20000 ppm F1 and F2 pups.
Ref: TSCA Health & Safety Study
Cover Sheet "Public Display Copy"
http://www.epa.gov/opptintr/tsca8e/doc/8ehq/2004/november04/8ehq-1004-15768a.pdf
••
This
document was cited at EPA's
site: "TSCA 8(e) and FYI Submissions Received from 11-15-04-11-26-04".
It is important to note this as the document itself does not identify
flubendiamide or its CAS No.
•• This
study was conducted in the laboratory of The Institute of Environmental
Toxicology - Japan
•• Source of Data/Study
Sponsor: Bayer Material Science Corporation, 100 Bayer Road, Pittsburg
PA 15205
Reproductive
/ Developmental (click
on for all fluorinated pesticides)
Results
of a reproductive toxicity study in rats (exposure route not stated):
1. Delayed sexual development
(preputial separation) in the 50
(considered incidental), 2000, and 20000 ppm F1 parental males.
2. Decreased sperm head count per testis
in F1 parental males
3. Increased incidence of eyeball enlargement
and dark-colored liver in 2000 and 20000 ppm F1 and F2
pups.
4. Thyroid, liver, uterine, thymus, and
spleen weight changes in 2000 and 20000 ppm F1 and F2 pups.
Ref: TSCA Health & Safety Study
Cover Sheet "Public Display Copy"
http://www.epa.gov/opptintr/tsca8e/doc/8ehq/2004/november04/8ehq-1004-15768a.pdf
••
This
document was cited at EPA's
site: "TSCA 8(e) and FYI Submissions Received from 11-15-04-11-26-04".
It is important to note this as the document itself does not identify
flubendiamide or its CAS No.
•• This
study was conducted in the laboratory of The Institute of Environmental
Toxicology - Japan
•• Source of Data/Study
Sponsor: Bayer Material Science Corporation, 100 Bayer Road, Pittsburg
PA 15205
Spleen
(click
on for all fluorinated pesticides)
Results
of a reproductive toxicity study in rats (exposure route not stated):
Thyroid, liver, uterine, thymus, and spleen
weight changes in 2000 and 20000 ppm F1 and F2 pups.
Ref: TSCA Health & Safety Study
Cover Sheet "Public Display Copy"
http://www.epa.gov/opptintr/tsca8e/doc/8ehq/2004/november04/8ehq-1004-15768a.pdf
••
This
document was cited at EPA's
site: "TSCA 8(e) and FYI Submissions Received from 11-15-04-11-26-04".
It is important to note this as the document itself does not identify
flubendiamide or its CAS No.
•• This
study was conducted in the laboratory of The Institute of Environmental
Toxicology - Japan
•• Source of Data/Study
Sponsor: Bayer Material Science Corporation, 100 Bayer Road, Pittsburg
PA 15205
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