Dimefox
CAS No. 115-26-4
 
 

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Adverse Effects
Abstracts
Toxicity

ACTIVITY: Acaracide, Insecticide (organophosphate)

NOTE: WHO: Believed to be obsolete or discontinued for use as pesticides (Note from FAN: it is permitted for use in India).

CAS Name: Tetramethylphosphorodiamidic fluoride

Structure:

Adverse Effects:

Brain
CNS
Genotoxic

Environmental Effects:

Moderately to highly toxic to fish

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No
US EPA PC Code: 443100
Registered use in
(includes only a limited list of countries)

India 
Use banned in: Thailand
European Commission: Not allowed to be used as an active ingredient after July 25, 2003.
Other Information
Molecular Formula: C4H12 F N2OP
Manufacturers: Aventis
Other Names: Too many to list here - see synonyms at bottom of page.
Of special interest:
PAN Data
TOXNET profile from Hazardous Substances Data Base
Extremely Hazardous Substance. US EPA Chemical Profile. October 31, 1985. Revised Nov. 30, 1987.
Included on The List of Extremely Hazardous Substances US 40 CFR - CHAPTER I - PART 355 - updated October 3, 2003
November 26, 2002 - European Commission: Dimefox is one of 320 pesticides to be withdrawn in July 2003. "Some 320 substances used in plant protection products (PPPs) including insecticides, fungicides and herbicides are to be withdrawn from the market by 25 July 2003 as part of the European Commission's new approach to the evaluation of active substances in plant protection products.
Abstracts
Toxicity
Believed to be obsolete or discontinued for use as pesticides. WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2000-2002. Table 6. Active ingredients not included in the Classification and believed to be obsolete or discontinued for use as pesticides, p 37.
Organophosphate Toxicity. Dimefox is a selective systemic insecticide which is absorbed into the plant sap and remains active for long periods of time. Michigan Wildlife Diseases Manual.
Glossary of Pesticide Chemicals, October 2001. A listing of pesticides subject to analysis of residues in foods and feeds by the US Food and Drug Administration. Also available at: http://vm.cfsan.fda.gov/~acrobat/pestglos.pdf

A highly toxic cholinesterase inhibitor.
[Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996. 542]

The no-effect dosage of dimefox based on the most sensitive criterion, red cell cholinesterase, is 0.002 mg/kg/day in humans.
[Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 2. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991. 974]

DIMEFOX IS INCL ON LIST OF COMPD CONSIDERED MOST DANGEROUS TO PESTICIDE APPLIERS.
/FROM TABLE/ [Sunshine, I. (ed.). CRC Handbook of Analytical Toxicology. Cleveland: The Chemical Rubber Co., 1969. 563]

Ref: mainly from: TOXNET profile for Dimefox from Hazardous Substances Data Base. http://www.fluorideaction.org/pesticides/dimefox.toxnet.hsdb.htm

Synonyms:

4-04-00-00283 (Beilstein Handbook Reference)
AI3-19109
BFP
BFPO
BRN 1704257
Bis(dimethylamido)-phosphoryl fluoride
Bis(dimethylamido)fluorophosphate
Bis(dimethylamino)fluorophosphate
Bisdimethylaminofluorophosphine oxide
CR 409
Caswell No. 843
DIFO
Dimefox
Dimefox [ISO]
EINECS 204-076-8
ENT 19,109
EPA Pesticide Chemical Code 443100
Fluophosphoric acid di(dimethylamide)
Fluorure de N,N,N',N'-tetramethyle phosphoro-diamide [French]
HSDB 1775
Hanane
N,N,N',N'-Tetramethyl-diamido-fluor-phosphin-oxid [German]
N,N,N',N'-Tetramethyl-diamido-fosforzuur-fluoride [Dutch]
N,N,N',N'-Tetramethyl-diamido-phosphorsaeure-fluorid [German]
N,N,N',N'-Tetrametil-fosforodiammido-fluoruro [Italian]
N,N,N,N-Tetramethylphosphorodiamidic fluoride
Pestox 14
Pestox IV
Pestox XIV
Phosphine oxide, bis(dimethylamino)fluoro-
Phosphorodiamidic fluoride, tetramethyl-
S-14
T-2002
TL 792
Terra-systam
Terra-sytam
Terrasytum
Tetra sytam
Tetramethyldiamidophosphoric fluoride
Tetramethylphosphorodiamidic fluoride
Wacker S 14/10

Systematic Name
Dimefox
Phosphorodiamidic fluoride, tetramethyl-

 
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