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Adverse Effects
Abstracts
NTIS
Reports
ACTIVITY: Insecticide,
Fungicide Propellant, EPA List 2 Inert (Halogenated
organic)
Also known as Freon
12
Structure:
Adverse
Effects:
Ataxia
Brain
CNS
Heart
Leukemia
Liver
Lung
Tremors/Convulsions |
Environmental
Effects:
Ozone
depleting substance
Very
resistant to chemical and biological degradation and likely
to be a persistent contaminant if it reaches groundwater.
Bioconcentration in organisms is low to moderate. |
Regulatory
Information
(only comprehensive for the US) |
US
EPA Registered: |
Yes |
US
EPA PC Code: |
000014
|
California
Chemical Code |
1459 |
Other
Information |
Manufacturers: |
Allied
Signal
DuPont
Elf Atochem |
Note: |
Has
not been manufactured in
the US since 1995 |
Other
Names: |
Freon
12, CFC 12,
Propellent 12, Frigen 12,
Arcton 12, FC 12,
Genetron 12, Ledon 12,
Eskimon 12
-- See more names in box below. |
Manufacture
site: |
US:
Allied
Signal Inc.
Prod site: Danville, IL 61834
Dupont Chemical Inc.
Prod sites:
-- Antioch, CA 94509;
-- Montague, MI 49437.
Elf Atochem North America Inc.
Prod site: Calvert
City, KT 42029. |
Of
special interest: |
PAN
Data |
TOXNET
profile from Hazardous Substances Data Bank |
September
24, 2003 (Revised). Released November 7, 2003 -
FREON [11, 12, 113].
Technical Support Document: Toxicology. Clandestine
Drug Labs/ Methamphetamine. Volume 1, Number 11. California
EPA, Office of Environmental Health Hazard Assessment (OEHHA),
Department of Toxic Substances Control. |
2000
-
Toxic Release Inventory.
Brief Summary. |
IRIS
- Integrated Risk Information System -
US EPA, May 1998 |
Occupational
Safety & Health Guideline - OSHA |
Insecticide
Products. Partial List. |
Abstracts |
NTIS
Reports |
National
Occupational Exposure Survey:
1981 - 1983 |
Synonyms |
AI3-01708
Algofrene type 2
Arcton 12
Arcton 6
CCRIS 3501
CFC 12
Caswell No. 304
Chlorofluorocarbon 12
Dichlorodifluoromethane
Diclorodifluometano [Spanish]
Difluorodichloromethane
Dwuchlorodwufluorometan [Polish]
Dymel 12
EINECS 200-893-9
|
Electro-CF
12
Eskimon 12
F 12
FC 12
FCC 12
FKW 12
Fluorocarbon-12
Forane 12
Freon 12
Freon F-12
Frigen 12
Genetron 12
HSDB 139 Halon
Halon 122 |
Isceon
122
Isotron 12
Isotron 2
Kaiser chemicals 12
Ledon 12
Methane, dichlorodifluoro-
Propellant 12
R 12 (refrigerant)
RCRA waste number U075
Refrigerant 12
Refrigerant R 12
Ucon 12
Ucon 12/halocarbon 12
|
US
EPA List of Inerts. This
substance is on List
2
Note:
US EPA allows so-called "Inert" ingredients to be commonly
mixed with the "active" pesticidal ingredient to
create a formulated pesticide product. According
to EPA, "The term `inert' is not intended to imply
nontoxicity; the ingredient may or may not be chemically active."
"Inert" ingredients include solvents, emulsifiers,
spreaders, and other substances mixed into pesticide products
to increase the effectiveness of the active ingredients, make
the product easier to apply, or to allow several active ingredients
to mix in one solution. Both US EPA and California Department
of Pesticide Regulation require pesticide manufacturers to
identify inert ingredients in their products but do not disclose
this information to the general public because the pesticide
industry considers product formulations trade secrets, protected
by law and by the US EPA. The US EPA category of Inerts (as
of September 2003):
List 1 - Of Toxicological
Concern
List 2 -
Potentially Toxic / High Priority for Testing
List
3 - Of Unknown Toxicity
List 4A - Generally Regarded as Safe
List 4B - EPA states it has Sufficient Information to Reasonably
Conclude that the Current Use Pattern in Pesticide Products
will not Adversely Affect Public Health or the Environment
List 4 (all)
See
good report: Toxic
Secrets": "Inert" Ingredients in Pesticides
1987-1997, published by Northwest
Coalition for Alternatives to Pesticides. |
US
Federal Register |
Date
Published |
Docket
Identification Number |
Details |
August
3, 2005 |
OPP-2005-0068 |
Inert
ingredients; Revocation of Pesticide Tolerance Exemptions
for Three CFC Chemicals. FINAL RULE.
EPA is revoking exemptions from the requirement of
a tolerance for three inert ingredients (dichlorodifluoromethane,
dichlorotetrafluoroethane, and trichlorofluoromethane)
because these substances no longer have active Federal Insecticide,
Fungicide, and Rodenticide Act (FIFRA) pesticide product registrations
and/or because their use in pesticide
products sold in the United States (U.S.) has been prohibited
under the Clean Air Act (CAA) for over a decade due to EPA's
ban on the sale or distribution, or offer for sale or distribution
in interstate commerce of certain nonessential products that
contain or are manufactured with ozone depleting compounds...
Nonetheless,
EPA will establish and maintain tolerances and tolerance exemptions
even when corresponding domestic uses are canceled if the
tolerances, which EPA refers to as ``import tolerances,''
are necessary to allow
importation into the United States of food containing such
pesticide residues.
However, where there are no imported commodities that require
these import tolerances, the Agency believes it is appropriate
to revoke tolerances and tolerance exemptions for unregistered
pesticide chemicals in order to prevent potential misuse.
40 CFR
chapter I is amended as follows:
PART 180--[AMENDED]
•
1. The authority citation for part 180 continues to read as
follows:
Authority: 21 U.S.C. 321(q), 346a and 371.
• 2. Section 180.910
is amended by removing the following exemptions and
any associated Limits and Uses from the table: Dichlorodifluoromethane,
Dichlorotetrafluoroethane, and Trichlorofluoromethane.
• 3. Section 180.930 is
amended by removing the following exemptions and
any associated Limits and Uses from the table: Dichlorodifluoromethane
and Trichlorofluoromethane. |
April 27,
2005 |
OPP-2005-0068 |
Inert
Ingredients; Proposal to Revoke Pesticide Tolerance.
EPA is proposing to revoke exemptions from the requirement
of a tolerance for three inert ingredients (dichlorodifluoromethane,
dichlorotetrafluoroethane, and trichlorofluoromethane)
because these
substances are no longer in active Federal Insecticide, Fungicide,
and Rodenticide Act (FIFRA) pesticide product registrations
and/or their use in pesticide products sold in the U.S. has
been prohibited under the Clean Air Act for over a decade
by EPA's ban on the sale or distribution, or offer for sale
or distribution in interstate commerce
of certain nonessential products that contain or are manufactured
with ozone depleting compounds. These ingredients are
subject to reassessment by August, 2006 under section 408(q)
of the Federal Food,
Drug, and Cosmetic Act (FFDCA), as amended by the Food Quality
Protection Act of 1996 (FQPA).
Therefore,
it is proposed that 40 CFR part 180 be amended as follows:
PART 180--AMENDED
1. The authority citation for part 180 continues to read as
follows:
Authority: 21 U.S.C. 321(q), 346a and 371.
Sec. 180.910 [Amended]
2. Section 180.910 is amended
by removing the following exemptions
and any associated Limits and Uses from the table:
Dichlorodifluoromethane, Dichlorotetrafluoroethane,
and
Trichlorofluoromethane.
Sec. 180.930 [Amended]
3. Section 180.930 is amended
by removing the following exemptions
and any associated Limits and Uses from the table:
Dichlorodifluoromethane and Trichlorofluoromethane. |
April 28,
2004 |
OPP-2003-0368 |
Pesticides;
Tolerance Exemptions for Active and Inert Ingredients for Use
in Antimicrobial Formulations (Food-Contact Surface Sanitizing
Solutions). FINAL RULE.
--
Propellant
- used in pesticide formulations
applied to growing crops or to raw agricultural commodities
after harvest; and in pesticide
formulations applied to animals.
|
June
21, 2001 |
RSPA-2000-7702
(HM-215D) |
Hazardous
Materials Regulations for
Fluoride substances. Harmonization of international shipment
of Dangerous Goods. Final Rule. |
June
24, 1998 |
OPP-
36192 |
US
EPA List 2 Inert; Ingredient in Pesticide Products. |
|