• The Danger of Taking Prozac The Guardian September 4, 1999
• Book: Talking Back to Prozac Peter R. Breggin, M.D.
• Prozac Backlash: Long-Term Consequences for Taking Antidepressants Are Virtually Unknown ABC News April 10, 2000
• Antidepressants linked to sexual side effects CNN.com Health with WebMD February 9, 2000
• Fluoextine: Drug Monograph MentalHealth.com, Phillip Long, MD, 1999
• Manufacturer's Report (pdf) Eli Lilly, June 1998

Note on Prozac: One impact of prozac which is of particular concern is it's impact on the thyroid. Eli Lilly, the company that produces Prozac, reports that hypothyroidism can result from taking prozac, although the company states that such cases are infrequent (see Manufacturer's Report listed above). According to Henry Ford Health System, "The product information of Prozac reveals that infrequently Prozac may cause or worsen preexisting hypothyroidism. As hypothyroidism is known to cause depression, it is important to have your thyroid function checked." According to Mary Shomon, author of Living Well With Hypothyroidism, "Taking thyroid hormone replacement while taking the popular antidepressant sertraline -- brand name Zoloft -- can cause a decrease in the effectiveness of the thyroid hormone replacement, and make your TSH rise. This same effect has also been seen in patients receiving other selective serotonin-reuptake inhibitors such as Paxil (paroxetine) and Prozac (fluoxetine). If you are on an antidepressant or thyroid hormone and your doctor wants to prescribe the other, be sure to discuss these issues."

Since hypothyroidism is a common cause of depression, there is concern that patients with hypothyroidism may be prescribed prozac to treat their depression, which could in turn make their hypothyroidism worse.