http://www.apistan.com/msds_specimen/msds.htmlDate Issued: February 1998
Supercedes: April, 1996MATERIAL SAFETY DATA SHEET
ZOECON® APISTAN® ANTI-VARROA MITE STRIP
Manufacturer: Wellmark International
Address: 1000 Tower Lane, Suite 245, Schaumburg, Illinois 60106
Emergency Phone: 1-800-248-7763
Transportation Emergency Phone: CHEMTREC: 1-800-424-9300
Product Name: Zoecon® Apistan® Anti-Varroa Mite Strip
Chemical Name/Synonym: tau-Fluvalinate: (RS)--cyano-3-phenoxybenzl N-(2-chloro-
Chemical Family: Synthetic Pyrethroid
Formula: C26 H22 CI F3 N2 O3
EPA Registration No.: 2724-406
RF Number: 318G
Inventory Control Number: 86055F
| Component
|
CAS Number | Weight | Tolerance |
| tau-Fluvalinate:
(RS)--cyano-3-phenoxybenzl
N-(2-chloro- ,,,-trifluoro-p-tolyl)-D-valinate |
102851-06-9 |
10.00% |
Not
established |
| Inert
ingredients (nonhazardous/trade secret) |
90.00% |
Not established |
| PRECAUTIONARY
STATEMENT |
SIGNS AND SYMPTOMS OF OVEREXPOSURE
Clinical symptoms may include salivation, depression, labored breathing, diarrhea. In certain individuals, a temporary sensory effect (itching, tingling, numbness) may occur which usually subsides without medical-treatment.PRIMARY ROUTE OF ENTRY
Dermal/Eye: Yes
Oral: No
Inhalation: NoACUTE TOXICITY
Oral: LD50 (rat): > 3000 mg/kg/bwt (highest dose level tested)
Dermal: LD50 (rabbit): > 2000 mg/kg/bwt (highest dose level tested)
Inhalation: Not knownOTHER TOXICOLOGICAL INFORMATION
Skin Irritation: Slight (rabbit), may cause temporary peripheral sensory phenomenon (paresthesia) in some individuals.
Eye Irritation: Mild (rabbit)
Sensitizer: Non-sensitizing
Eye: Very unlikely to occur due to product form. If eye contact should occur, flush immediately with water. If irritation persists, get medical attention.
Skin: Wash thoroughly with soap and water. If irritation appears consult a physician.
Ingestion: Very unlikely to occur due to product form. If swallowed, contact physician.
Inhalation: Very unlikely to occur due to product form.
Note to Physician: Treat symptomatically.
NFPA Rating:
Health: 1
Flammability Class: Combustible solid
Flash Point: Not applicable
Explosive Limits (% of Volume): Not established
Extinguishing Media: Water, CO2, dry chemical, foam
Special Protective Equipment: Firefighters should wear full protective clothing and self contained breathing apparatus.
Fire Fighting Procedures: Normal procedures. Do not allow fire fighting water to escape into waterways or sewers.
Combustion Products: Hydrogen cyanide, hydrogen chloride and hydrogen fluoride may form on burning.
Unusual Fire/Explosion Hazards: None known
Steps to be taken: None needed due to product form and packaging
Absorbents: Due to product form, no absorbents should be necessary
Incompatibles: Strong oxidizing agents
Handling: Wear gloves (e.g. latex) when handling the strips. Wash hands, face and arms thoroughly with soap and water after handling product.
Storage: Do not contaminate water, food, or feed by storage. Store in unopened protective pouch. Do not open pouch until ready to use. Do not store unused strips in anything but original package. Do not store in direct sun light.
Exposure Limits: Not established
Ventilation: Use with adequate ventilation.
Personal Protective Equipment: Wear gloves (e.g. latex) when handling the strips. Wash hands, face and arms thoroughly with soap and water after handling product.
Appearance and Odor: Light golden colored, clear plastic strip, very low odor.
Boiling Point: Not applicable
Melting Point: Not determined
Vapor Pressure (mm Hg): Not determined
Vapor Density (Air = 1): N/A
Specific Gravity: N/A
Bulk Density: N/A
Solubility: None
Evaporation Rate: N/A
pH: N/A
Stability: Stable
Reactivity: Non-reactive
Incompatibility with Other Materials: Strong oxidizing agents
Decomposition Products: Hydrogen cyanide, hydrogen fluoride, hydrogen chloride, carbon monoxide, carbon dioxide
Hazardous Polymerization: Will not occur
CHRONIC TOXICITY [Specific to Active Ingredient(s)]
Rats received tau-fluvalinate via gavage. No oncogenic potential was shown. The NEL was 1 mg/kg/day. Mice were fed diets containing tau-fluvalinate. With the exception of skin lesions, no compound-related toxicity was observed. No oncogenic potential was shown. The systemic NOEL was considered to be 20/mg/kg/day. Dogs were treated with racemic tau-fluvalinate daily for six months. Vomiting and diarrhea occurred at 50 mg/kg/day and skin lesions at the 3 highest levels. The NEL was determined to be 2 mg/kg/day.DEVELOPMENTAL/REPRODUCTIVE TOXICITY [Specific to Active Ingredient(s)]
Rats were administered racemic tau-fluvalinate during presumed gestation. The developmental NEL was 10 mg/kg/day. Skin lesions were observed at 100 ppm and above. Treatment-related mortality occurred at 500 and 1000 ppm. In the first generation, pup growth was inhibited at levels of 250 ppm and above during lactation. The NEL was 20 ppm. Rabbits were administered tau-fluvalinate during presumed gestation. Signs of maternal toxicity were anorexia, depression, and decreased body weights. The NEL was 25 mg/kg/day.MUTAGENICITY [Specific to Active Ingredient(s)]
The weight of evidence suggests tau-fluvalinate is not a mutagen.OTHER
In rats, oral administration of 60 mg/kg daily for 7 consecutive days resulted in histopathological evidence of neurotoxocity in the peripheral nervous system. However, the changes were not persistent and were no longer evident following 2 weeks without treatment.
ENVIRONMENTAL FATE [Active Ingredients Only]
Hydrolysis: Main mechanism of dissipation at basic pH
Photolysis: Degraded rapidly in sunlight and artificial light
Soil half life: 6-15 days depending on soil type and oxygen
Water solubility: 0.002 mg/L at 25CECOTOXICITY [Active Ingredients Only]
Acute Toxicity: fish:LC50 (rainbow trout): 2.7 ug/L (96 hour study); (bluegill): 6.2 ug/L (96 hour study); aquatic invertebrates:LC50 (Daphnia Magna): 1.0 ug/L (48 hour study)
Do not contaminate water, food, or feed by disposal. Do not reuse container or used strip. If household waste, wrap and put in trash. If large numbers of strips are to be discarded, dispose of in an approved landfill or incinerator. In all cases, it is best to consult local authorities as to appropriate disposal procedures and locations.
DOT49CFR Description: Not regulated as hazardous by D.O.T.
Freight Classification: Insecticide, NOI, other than poison in boxes. NMFC 102120
CERCLA (Superfund): Not regulated
RCRA: Not regulated as hazardousSARA 311/312 HAZARD CATEGORIES
Immediate Health: Yes (irritation)
Delayed Health: No
Fire: No
Sudden Pressure: No
Reactivity: NoThe information presented herein, while not guaranteed, was prepared by technically knowledgeable personnel and to the best of our knowledge is true and accurate. It is not intended to be all inclusive and the manner and conditions of use and handling may involve other or additional considerations.