Siloxanes and silicones, Me 3,3,3-trifluoropropyl (63148-56-1). Index from Fluoride Action Network Pesticide Project.

Siloxanes and silicones, Me 3,3,3-trifluoropropyl
CAS No. 63148-56-1

ACTIVITY: US EPA List 3 Inert

Name of Substance: Fluorosilicone oil

Systematic Name: Siloxanes and Silicones, Me 3,3,3-trifluoropropyl

Regulatory Information (only comprehensive for the US)
US EPA Registered:	Yes - List 3 Inert
Registered use in (includes only a limited list of countries)	US
Other Information
Molecular Formula:	Unspecified
Manufactuer:	Dow Corning
Of special interest:
See Material Safety Data Sheets
Note from FAN: If you have any of the reports listed below, please share them with us. Thanks. EC.
1994. ACARICIDAL AND INSECTICIDAL ACTIVITY OF VARIOUS SILICONE FLUIDS WITH COVER LETTER DATED 04/20/94 Source: EPA/OTS; Doc #86940001218 Order Number: NTIS/OTS0572228
1985. ACARICIDAL AND INSECTICIDAL ACTIVITY OF VARIOUS SILICONE FLUIDS Source: EPA/OTS; Doc #878215084 Order Number: NTIS/OTS0206762
1994. ORGANOSILICON INSECT TOXICANTS WITH COVER LETTER DATED 04/20/94 Source: EPA/OTS; Doc #86940001494 Order Number: NTIS/OTS0572741
1994. EFFECTS OF THREE SILICONES ON THE REPRODUCTIVE ORGANS OF MALE RATS AND RABBITS WITH COVER LETTER DATED 04/20/94 Source: EPA/OTS; Doc #86940001840 Order Number: NTIS/OTS0572824
1994. THE RESULTS OF RANGE FINDING STUDIES ON SEVERAL DOW CORNING SILOXANE MONOMERS, POLYMERS AND CYCLIC INTERMEDIATES WITH COVER LETTER DATED 042094 Source: EPA/OTS; Doc #86940001043 Order Number: NTIS/OTS0556497
1994. REPORT TO DOW CORNING CORPORATION 30-DAY DERMAL TOXICITY STUDY WITH DOW CORNING FOOT PROTECTOR AND FOOT PROTECTOR VEHICLE IN RHESUS MONKEYS WITH COVER LETTER DATED 042094 Corporate Name: INDUS BIO-TEST LABS INC Source: EPA/OTS; Doc #86940001096 Order Number: NTIS/OTS0556550
1994. REPORT TO DOW CORNING CORPORATION SUBACUTE PERCUTANEOUS TOXICITY OF TX-36 WITH COVER LETTER DATED 042094 Corporate Name: INDUS BIO-TEST LABS INC Source: EPA/OTS; Doc #86940001052 Order Number: NTIS/OTS0556506
1994. THE TOXICITY TO RATS OF VAPORS RESULTING FROM HEATING OF SILICON CONTAINING FLUIDS WITH COVER LETTER DATED 042094 Source: EPA/OTS; Doc #86940001042 Order Number: NTIS/OTS0556496
1992. INITIAL SUBMISSION: LETTER FROM GENERAL ELECTRIC COMPANY SUBMITTING A BATTERY OF TOXICITY STUDIES WITH SILICONES IN MAMMALS WITH ATTACHMENTS Source: EPA/OTS; Doc #88-920003309 Order Number: NTIS/OTS0539961
1985. ENVIRONMENTAL EFFECTS OF SIMULATED SPILLS OF TWELVE DOW CORNING SILICONE FLUIDS. I. ROW APPLICATION AS TWENTY-FIVE PERCENT AQUEOUS EMULSIONS Source: EPA/OTS; Doc #878215085 Order Number: NTIS/OTS0206762
1985. ENVIRONMENTAL EFFECTS OF SILICONE FLUIDS. II-APPLIED AS PURE FLUIDS Source: EPA/OTS; Doc #878215086 Order Number: NTIS/OTS0206762
1985. ENVIRONMENTAL EFFECTS OF SILICON FLUIDS ON PLANTS IN A TERRESTRIAL ENVIRONMENT: ONE YEAR AFTER FLUID APPLICATION Source: EPA/OTS; Doc #878215087 Order Number: NTIS/OTS0206762
1994. ENVIRONMENTAL EFFECTS OF SIMULATED SPILLS ON TWELVE DOW CORNING SILICONE FLUIDS. IV. EFFECTS ON THE INVERTEBRATE FAUNA OF SOIL AND HUMUS WITH COVER LETTER DATED 04/20/94 Source: EPA/OTS; Doc #86940001227 Order Number: NTIS/OTS0572236
1994. ENVIRONMENTAL EFFECTS OF SIMULATED SPILLS ON 12 DOW CORNING SILICONE FLUIDS. III. EFFECTS OF SPILLS ON SUBSEQUENT GERMINATION OF SEEDS COLLECTED* W/COVER LETTER DATED 04/20/94 Source: EPA/OTS; Doc #86940001228 Order Number: NTIS/OTS0572237
1994. THE TOXICITY TO RATS OF VAPORS RESULTING FROM HEATING OF SILICON CONTAINING FLUIDS WITH COVER LETTER DATED 042094 Source: EPA/OTS; Doc #86940001042 Order Number: NTIS/OTS0556496
1994. SEVEN DAY SUBACUTE DERMAL TOXICITY STUDY ON THREE FOOT PROTECTOR FORMULATIONS MDX-4-4143, MDX-4-4144, AND MDX-4-4145 WITH COVER LETTER DATED 042094 Source: EPA/OTS; Doc #86-940001134 Order Number: NTIS/OTS0556588
1987. EFFECTS OF INTRAVITREAL INJECTION OF FLUOROSILICONE OIL AFTER VITRECTOMY IN THE RABBIT EYE Authors: PAYLOR R, PEYMAN GA, BADRI S Source: CAN J OPHTHALMOL; 22 (5). 1987. 251-253.
Adverse Effects: As of Dec 2003: No data accessible

US EPA List of Inerts. This substance is on List 3.

Note: US EPA allows so-called "Inert" ingredients to be commonly mixed with the "active" pesticidal ingredient to create a formulated pesticide product. According to EPA, "The term `inert' is not intended to imply nontoxicity; the ingredient may or may not be chemically active." "Inert" ingredients include solvents, emulsifiers, spreaders, and other substances mixed into pesticide products to increase the effectiveness of the active ingredients, make the product easier to apply, or to allow several active ingredients to mix in one solution. Both US EPA and California Department of Pesticide Regulation require pesticide manufacturers to identify inert ingredients in their products but do not disclose this information to the general public because the pesticide industry considers product formulations trade secrets, protected by law and by the US EPA. The US EPA category of Inerts (as of September 2003):

List 1 - Of Toxicological Concern
List 2 - Potentially Toxic / High Priority for Testing
List 3 - Of Unknown Toxicity
List 4A - Generally Regarded as Safe
List 4B - EPA states it has Sufficient Information to Reasonably Conclude that the Current Use Pattern in Pesticide Products will not Adversely Affect Public Health or the Environment
List 4 (all)

See good report: Toxic Secrets": "Inert" Ingredients in Pesticides 1987-1997, published by Northwest Coalition for Alternatives to Pesticides.

Material Safety Data Sheets (MSDS):
Name of Product	Manufacturer / Distributor	MSDS
Vac Goop® Antiseize thread lubricant	Svagelok Company	MSDS
MED-400	NuSil Technology	MSDS

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