http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15624354
J UOEH. 2004 Dec 1;26(4):423-30.
Tumor-promoting activity and mutagenicity
of 5 termiticide compounds.
Goto S, Asada S, Fushiwaki Y, Mori Y,
Tanaka N, Umeda M, Nakajima D, Takeda K.
Research Center for Material Cycles and Waste Management, National
Institute for Environmental Studies, Onogawa, Tsukuba, Ibaraki
305-8506, Japan.
The tumor-promoting activities of 5 commercial compounds used
in termiticides were measured by a cell-transformation assay
employing Bhas 42 cells. Their initiating activities were also
measured by the microsuspension assay employing S. typhimurium
TA98 and TA100 strains. The results of the transformation assay
confirmed the tumor-promoting activities
of fenitrothion, silafluofen and
bifenthrin. Furthermore, the mutagenicity of S-421 and fenitrothion
were also confirmed. Consideration of
2-stage carcinogenesis suggests that concurrent use of and long-term
exposure to these compounds that have tumor-promoting and initiator
activity, and compounds exhibiting either type of activity individually
should be avoided as much as possible.
PMID: 15624354 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12749190
Shokuhin Eiseigaku Zasshi. 2003
Feb;44(1):7-12.
[Effects of rice cleaning and cooking
process on the residues of flutolanil, fenobucarb, silafluofen
and buprofezin in rice]
[Article in Japanese]
Satoh M, Sakaguchi M, Kobata M, Sakaguchi
Y, Tanizawa H, Miura Y, Sasano R, Nakanishi Y.
Saika Technological Institute Foundation: 75-2, Kuroda, Wakayama-shi
640-8341, Japan.
We studied the effect of cleaning and cooking on the residues
of flutolanil, fenobucarb, silafluofen
and buprofezin in rice. The rice had been sprayed in a paddy
field in Wakayama city, with 3 kinds of pesticide application
protocols: spraying once at the usual concentration of pesticides,
repeated spraying (3 times) with the usual concentration of
pesticides and spraying once with 3 times the usual concentration
of pesticides. The residue levels of pesticide decreased during
the rice cleaning process. Silafluofen,
which has a higher log Pow value, remained in the hull of the
rice. Fenobucarb, which has a lower log Pow value, penetrated
inside the rice. The residue concentration of pesticide in polished
rice was higher than that in pre-washed rice processed ready
for cooking. During the cooking procedure, the reduction of
pesticides in polished rice was higher than that in brown rice.
PMID: 12749190 [PubMed - indexed for MEDLINE]
Full free article available at http://rent11.combox.de/journals/holz/2003/pdf/57_585.pdf
Holzforschung - Volume 57, Issue 6 (2003)
Termiticidal Performance of Wood-Based
Composites Treated with Silafluofen
Using Supercritical Carbon Dioxide
M. Muin and K. Tsunoda
Wood Research Institute, Kyoto University,
Kyoto, Japan
The termiticidal performance of wood-based composites [medium
density fiberboard (MDF), hardwood plywood, softwood plywood,
particleboard and oriented strand board (OSB)] was evaluated
following treatment with a non-ester pyrethroid, silafluofen,
using supercritical carbon dioxide (SC-CO2) as a carrier solvent.
Treatment was conducted under nine combinations of temperature
(35 °C, 45 °C or 55 °C) and pressure [7.85 MPa (80
kgf/cm2), 9.81 MPa (100 kgf/cm2) or 11.77 MPa (120 kgf/cm2)].
Treated and untreated samples were individually exposed to the
subterranean termite Coptotermes formosanus Shiraki in the laboratory,
and the percent mass loss of the samples and termite mortality
were determined to compare the termiticidal performance among
the wood-based composites and treatment conditions. Silafluofen/SC-CO2
treatment significantly improved the termite resistance of all
of the wood-based composites, although the termiticidal performance
varied with the composite type and treatment conditions. The
best performance for MDF, hardwood plywood, softwood plywood
and particleboard was obtained at 35 °C-7.85 MPa in terms
of the inhibition of feeding, and gave high termite mortality
and energy-conservation, whereas the best performance for OSB
was at 35 °C and 9.81 MPa or 11.77 MPa.
From Toxline at Toxnet
MATERIAL UND ORGANISMEN (BERLIN); 30 (2). 1996.
133-142.
Degradation of termiticides and its
effect on performance against Thailand's economically most important
subterranean termite, Coptotermes gestroi Wasmann (Isoptera:
Rhinotermitidae): I. Soil burial.
SORNNUWAT Y, VONGKALUANG C, YOSHIMURA
T, TSUNODA K, TAKAHASHI M
Forest Prod. Res. and Dev., Royal Forest Dep., Chatuchak, Bangkok
10900, Thailand.
Effect of soil burial on recovery rates and termiticidal effectiveness
of three synthetic pyrethroids (cypermethrin, fenvalerate and
permethrin), the silane (silafluofen)
and an organophosphate (chlorpyrifos) when treated wood blocks
were buried in soil was investigated. All the chemicals degraded
with time, and the loss of effectiveness was especially evident
for blocks treated at lower concentrations. Chlorpyrifos degraded
more rapidly than the other termiticides in test, and the recovery
rates decreased less than 10% after 3 months even at the highest
concentration. Silafluofen showed the
highest resistance to soil burial, followed by the three
synthetic pyrethroids. Results of bioassays using the most economically
important subterranean termite in Thailand, Coptotermes gestroi
Wasmann, agreed favourably with the results of recovery rates
of termiticides, and showed the possibility of using all test
chemicals as alternative termiticides in the country.
From Toxline at Toxnet
MATERIAL UND ORGANISMEN (BERLIN); 30 (2). 1996.
143-154.
Degradation of termiticides and its
effect on performance against Thailand's economically most important
subterranean termite, Coptotermes gestroi Wasmann (Isoptera:
Rhinotermitidae): II. Indoor and outdoor
exposure in above ground situation.
SORNNUWAT Y, VONGKALUANG C, YOSHIMURA
T, TSUNODA K, TAKAHASHI M
Forest Prod. Res. and Dev., Royal Forest Dep., Chatuchak, Bangkok
10900, Thailand.
Experiments were conducted to evaluate the chemical degradation
and the change of termiticidal performance of three synthetic
pyrethroids (cypermethrin, fenvalerate and permethrin), the
silane (silafluofen) and the organophosphate (chlorpyrifos)
treated wood blocks after certain periods of indoor and outdoor
exposure in above ground situation. From the mass losses of
untreated wood blocks, the outdoor weathering seemed to be more
severe than the indoor weathering. Natural weathering consisting
of ultraviolet irradiation and other unspecified variables exerted
less effects on the recovery rates and the termiticidal effectiveness
of all chemicals than when buried in soil. All chemicals at
every concentration provided good termiticidal performance (less
than 3% wood consumption of treated blocks) even after 24 months'
indoor weathering, but only 6 months' for outdoor weathering.
Chlorpyrifos degraded more rapidly than the other termiticides
in both indoor and outdoor weath [abstract truncated]
CAS Registry Numbers:
105024-66-6
105024-66-6
52645-53-1
52315-07-8
51630-58-1
2921-88-2
From Toxline at Toxnet
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY; 49 (2). 1994.
83-93.
Neurophysiological effects and quantitative
structure-activity analyses of insecticidal silaneophanes.
OKIMOTO H, NISHIMURA K, MATSUDA K, HAMADA
M, UENO T, FUJITA T
Dep. Agric. Chem., Kyoto Univ., Kyoto 606-01, JAP.
Silaneophanes containing a quaternary silicon connected to variously
substituted phenyl groups were shown to prolong the sodium residual
and tail currents in the crayfish giant axon under voltage clamp
conditions, sharing characteristics common to conventional pyrethroids.
Insecticidal activity of these compounds was measured against
American cockroaches. Variations in the insecticidal activity
measured under conditions to inhibit the oxidative metabolic
mechanism were analyzed quantitatively. It was found that insecticidal
activity was linearly related to the crayfish tail-current prolongation
activity when the transport factors of compounds were allowed
for by use of a hydrophobicity parameter. The higher the tail-current
prolongation activity, the higher the insecticidal activity.
Variations in the insecticidal activity were also correlated
with physicochemical substituent parameters, indicating that
the longer the substituents on the benzene ring, the higher
the act
CAS Registry Numbers:
105024-66-6
105024-66-6
89764-44-3
80844-07-1
66230-04-4
52918-63-5
39515-40-7
26002-80-2
7696-12-0