Abstracts
Silafluofen
CAS No. 105024-66-6
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ACTIVITY: Insecticide, Termiticide, Wood preservative (pyrethroid)

CAS Name: (4-ethoxyphenyl)[3-(4-fluoro-3-phenoxyphenyl)propyl]dimethylsilane

Structure:

 

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15624354

J UOEH. 2004 Dec 1;26(4):423-30.

Tumor-promoting activity and mutagenicity of 5 termiticide compounds.

Goto S, Asada S, Fushiwaki Y, Mori Y, Tanaka N, Umeda M, Nakajima D, Takeda K.

Research Center for Material Cycles and Waste Management, National Institute for Environmental Studies, Onogawa, Tsukuba, Ibaraki 305-8506, Japan.

The tumor-promoting activities of 5 commercial compounds used in termiticides were measured by a cell-transformation assay employing Bhas 42 cells. Their initiating activities were also measured by the microsuspension assay employing S. typhimurium TA98 and TA100 strains. The results of the transformation assay confirmed the tumor-promoting activities of fenitrothion, silafluofen and bifenthrin. Furthermore, the mutagenicity of S-421 and fenitrothion were also confirmed. Consideration of 2-stage carcinogenesis suggests that concurrent use of and long-term exposure to these compounds that have tumor-promoting and initiator activity, and compounds exhibiting either type of activity individually should be avoided as much as possible.

PMID: 15624354 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12749190

Shokuhin Eiseigaku Zasshi. 2003 Feb;44(1):7-12.

[Effects of rice cleaning and cooking process on the residues of flutolanil, fenobucarb, silafluofen and buprofezin in rice]

[Article in Japanese]

Satoh M, Sakaguchi M, Kobata M, Sakaguchi Y, Tanizawa H, Miura Y, Sasano R, Nakanishi Y.

Saika Technological Institute Foundation: 75-2, Kuroda, Wakayama-shi 640-8341, Japan.

We studied the effect of cleaning and cooking on the residues of flutolanil, fenobucarb, silafluofen and buprofezin in rice. The rice had been sprayed in a paddy field in Wakayama city, with 3 kinds of pesticide application protocols: spraying once at the usual concentration of pesticides, repeated spraying (3 times) with the usual concentration of pesticides and spraying once with 3 times the usual concentration of pesticides. The residue levels of pesticide decreased during the rice cleaning process. Silafluofen, which has a higher log Pow value, remained in the hull of the rice. Fenobucarb, which has a lower log Pow value, penetrated inside the rice. The residue concentration of pesticide in polished rice was higher than that in pre-washed rice processed ready for cooking. During the cooking procedure, the reduction of pesticides in polished rice was higher than that in brown rice.

PMID: 12749190 [PubMed - indexed for MEDLINE]


Full free article available at http://rent11.combox.de/journals/holz/2003/pdf/57_585.pdf

Holzforschung - Volume 57, Issue 6 (2003)

Termiticidal Performance of Wood-Based Composites Treated with Silafluofen Using Supercritical Carbon Dioxide

M. Muin and K. Tsunoda

Wood Research Institute, Kyoto University, Kyoto, Japan

The termiticidal performance of wood-based composites [medium density fiberboard (MDF), hardwood plywood, softwood plywood, particleboard and oriented strand board (OSB)] was evaluated following treatment with a non-ester pyrethroid, silafluofen, using supercritical carbon dioxide (SC-CO2) as a carrier solvent. Treatment was conducted under nine combinations of temperature (35 °C, 45 °C or 55 °C) and pressure [7.85 MPa (80 kgf/cm2), 9.81 MPa (100 kgf/cm2) or 11.77 MPa (120 kgf/cm2)]. Treated and untreated samples were individually exposed to the subterranean termite Coptotermes formosanus Shiraki in the laboratory, and the percent mass loss of the samples and termite mortality were determined to compare the termiticidal performance among the wood-based composites and treatment conditions. Silafluofen/SC-CO2 treatment significantly improved the termite resistance of all of the wood-based composites, although the termiticidal performance varied with the composite type and treatment conditions. The best performance for MDF, hardwood plywood, softwood plywood and particleboard was obtained at 35 °C-7.85 MPa in terms of the inhibition of feeding, and gave high termite mortality and energy-conservation, whereas the best performance for OSB was at 35 °C and 9.81 MPa or 11.77 MPa.


From Toxline at Toxnet

MATERIAL UND ORGANISMEN (BERLIN); 30 (2). 1996. 133-142.

Degradation of termiticides and its effect on performance against Thailand's economically most important subterranean termite, Coptotermes gestroi Wasmann (Isoptera: Rhinotermitidae): I. Soil burial.

SORNNUWAT Y, VONGKALUANG C, YOSHIMURA T, TSUNODA K, TAKAHASHI M

Forest Prod. Res. and Dev., Royal Forest Dep., Chatuchak, Bangkok 10900, Thailand.

Effect of soil burial on recovery rates and termiticidal effectiveness of three synthetic pyrethroids (cypermethrin, fenvalerate and permethrin), the silane (silafluofen) and an organophosphate (chlorpyrifos) when treated wood blocks were buried in soil was investigated. All the chemicals degraded with time, and the loss of effectiveness was especially evident for blocks treated at lower concentrations. Chlorpyrifos degraded more rapidly than the other termiticides in test, and the recovery rates decreased less than 10% after 3 months even at the highest concentration. Silafluofen showed the highest resistance to soil burial, followed by the three synthetic pyrethroids. Results of bioassays using the most economically important subterranean termite in Thailand, Coptotermes gestroi Wasmann, agreed favourably with the results of recovery rates of termiticides, and showed the possibility of using all test chemicals as alternative termiticides in the country.


From Toxline at Toxnet

MATERIAL UND ORGANISMEN (BERLIN); 30 (2). 1996. 143-154.

Degradation of termiticides and its effect on performance against Thailand's economically most important subterranean termite, Coptotermes gestroi Wasmann (Isoptera: Rhinotermitidae): II. Indoor and outdoor exposure in above ground situation.

SORNNUWAT Y, VONGKALUANG C, YOSHIMURA T, TSUNODA K, TAKAHASHI M

Forest Prod. Res. and Dev., Royal Forest Dep., Chatuchak, Bangkok 10900, Thailand.

Experiments were conducted to evaluate the chemical degradation and the change of termiticidal performance of three synthetic pyrethroids (cypermethrin, fenvalerate and permethrin), the silane (silafluofen) and the organophosphate (chlorpyrifos) treated wood blocks after certain periods of indoor and outdoor exposure in above ground situation. From the mass losses of untreated wood blocks, the outdoor weathering seemed to be more severe than the indoor weathering. Natural weathering consisting of ultraviolet irradiation and other unspecified variables exerted less effects on the recovery rates and the termiticidal effectiveness of all chemicals than when buried in soil. All chemicals at every concentration provided good termiticidal performance (less than 3% wood consumption of treated blocks) even after 24 months' indoor weathering, but only 6 months' for outdoor weathering. Chlorpyrifos degraded more rapidly than the other termiticides in both indoor and outdoor weath [abstract truncated]

CAS Registry Numbers:
105024-66-6
105024-66-6

52645-53-1
52315-07-8
51630-58-1
2921-88-2


From Toxline at Toxnet

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY; 49 (2). 1994. 83-93.

Neurophysiological effects and quantitative structure-activity analyses of insecticidal silaneophanes.

OKIMOTO H, NISHIMURA K, MATSUDA K, HAMADA M, UENO T, FUJITA T

Dep. Agric. Chem., Kyoto Univ., Kyoto 606-01, JAP.

Silaneophanes containing a quaternary silicon connected to variously substituted phenyl groups were shown to prolong the sodium residual and tail currents in the crayfish giant axon under voltage clamp conditions, sharing characteristics common to conventional pyrethroids. Insecticidal activity of these compounds was measured against American cockroaches. Variations in the insecticidal activity measured under conditions to inhibit the oxidative metabolic mechanism were analyzed quantitatively. It was found that insecticidal activity was linearly related to the crayfish tail-current prolongation activity when the transport factors of compounds were allowed for by use of a hydrophobicity parameter. The higher the tail-current prolongation activity, the higher the insecticidal activity. Variations in the insecticidal activity were also correlated with physicochemical substituent parameters, indicating that the longer the substituents on the benzene ring, the higher the act

CAS Registry Numbers:
105024-66-6
105024-66-6

89764-44-3
80844-07-1
66230-04-4
52918-63-5
39515-40-7
26002-80-2
7696-12-0

 
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