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Adverse Effects
Abstracts
ACTIVITY: Insecticide,
Acaricide (pyrethroid)
CAS Name: (2-methyl[1,1?-biphenyl]-3-yl)methyl
3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate
Structure:

| |
| Published
Date |
Docket
Identification Number |
Details |
| October 24, 2007 |
EPA-HQ-OPP-2007-0471 |
IR-4. Pesticide tolerance. FINAL RULE.
Documents available with this Final Rule:
• Bifenthrin: Risk Assessment. Docket # EPA-HQ-OPP-2007-0471-0008
• Bifenthrin: Dietary Review. Docket # EPA-HQ-OPP-2007-0471-0007
• Bifenthrin: BEAD. Review Docket # EPA-HQ-OPP-2007-0471-0006
| Commodity |
PPM
FINAL RULE |
PPM
Requested |
Pesticide Petition Number |
Beet, garden, roots
|
0.45 |
same |
PP 6E7126 |
Beet, garden, tops
|
15 |
same |
PP 6E7126 |
| Grain, aspirated fractions |
70 |
None |
|
| Groundcherry |
0.5 |
None |
|
Mayhaw
|
1.4 |
same |
PP 6E7125 |
| Peanut |
0.05 |
same |
PP 6E7127 |
| Pepino |
0.5 |
None |
|
| Pistachio |
0.05 |
same |
PP 6E7127 |
| Radish, tops |
4.5 |
None |
|
Soybean, hulls
|
0.50 |
None |
|
Soybean, refined oil
|
0.30 |
None |
|
| Soybean, seed |
0.2 |
0.2
for "Soybean" |
PP 6E7128 |
Vegetable, root, subgroup 1B except sugar beet and garden beet
This subgroup includes 19 commodities: beet, garden • burdock, edible • carrot • carrot culls • celeriac • chervil, turnip rooted • chicory root • ginseng • horseradish • parsley, turnip rooted • parsnip • radish • radish, oriental • rutabaga • salsify • salsify, black • salsify, spanish • skirret • turnip |
0.10 |
0.07 |
PP 6E7126 |
Cancer. Bifenthrin was classified as a group ``C'' (possible human carcinogen). The Agency concluded that the chronic risk and exposure assessment, making use of the cPAD, to be protective of any potential carcinogenic risk. Therefore, no separate exposure assessment was conducted pertaining to cancer risk.
Note on Petiton for Vegetable, fruiting, group 8. Tolerances are established for residues of bifenthrin per se at 0.05 ppm in/on eggplant, at 0.15 ppm in/on tomato, and at 0.5 ppm in/on bell and non-bell pepper. EPA has determined that a fruiting vegetables crop group tolerance for residues of bifenthrin per se is not appropriate for the following reasons:
Maximum residues in eggplant are more than a factor of five lower than the tolerance for tomatoes and the use pattern for tomato and tomatillo are different from the other members of the crop group in terms of the PHI, maximum seasonal use rate, number of applications, and interval between applications. However, EPA is establishing tolerances for residues in/on groundcherry and pepino at 0.50 ppm based on the 0.5 ppm tolerance for bell and non-bell pepper. As 40 CFR 180.1 indicates that a tolerance for residues in/on tomato applies to tomatillo, a tolerance for residues in/on tomatillo is not required.
From July 25, 2007, Health Risk Assessment;
• Page 3. Bifenthrin is a neurotoxic insecticide acting through direct contact and ingestion, having a slight repellent effect. The primary biological effects of bifenthrin and other pyrethroids on insects and vertebrates are inhibition of the voltage-gated Ca 2+ channels coupled with a stimulatory effect on the voltage-gated Na+ channels. All pyrethroids act as axonic poisons, affecting both the peripheral and central nervous systems, and share similar modes of action. Pyrethroids, including bifenthrin, stimulate repetitive action in the nervous system by binding to voltage-gated sodium channels, prolonging the sodium ion permeability during the excitatory phase of the action potential. This action leads to spontaneous depolarizations, augmented neurotransmitter secretion rate and neuromuscular block, which ultimately results in paralysis of the insect.
• Page 4. Bifenthrin produces characteristic pyrethroid neurotoxicity. Tremors have been observed in developmental toxicity studies in the rat and rabbit, a 2-generation rat reproduction toxicity study, subchronic toxicity studies in the rat and dog, acute and subchronic neurotoxicity rat studies, a 21-day toxicity dermal rat study, chronic oral toxicity studies in the rat and dog, and a mouse oncogenicity study. The subchronic and chronic oral toxicity studies in dogs and rats demonstrate neurotoxicological responses of similar magnitude. Staggered gait and exaggerated hindlimb flexion were noted in a 21-day dermal toxicity study in the rat. The neurotoxicity of bifenthrin has been supported by the results of acute and subchronic neurotoxicity studies in the rat. Functional observation battery (FOB) findings were observed in these neurotoxicity studies. FOB findings consisted of tremors, abnormal posture, splayed hindlimbs, staggered gait, altered activity, altered landing foot-splay, twitching, uncoordinated movement/ataxia, and convulsions.
• Page 4. A developmental neurotoxicity (DNT) study on bifenthrin with rats has been submitted. In this study, maternal and offspring toxicity was observed at the same dose levels. The maternal toxicity was primarily manifested as tremors, clonic convulsions, and increased grooming counts. The offspring toxicity was manifested as increased grooming counts. This study does not show any evidence of increased susceptibility of offspring following exposure to bifenthrin.
• Pages 13-14. The CPRC (1992) has characterized bifenthrin as Category C (possible human carcinogen) and recommended that for the purpose of risk characterization, the RfD approach should be used for quantification of human cancer risk. This decision was based in part on the statistically significant increased trend for hemangiopericytomas in the urinary bladders’ of Swiss Webster mice. The incidence of these lesions was double at the highest dose tested (HDT; 600 ppm) as compared to controls. The male mice also had significant dose-related trends with respect to hepatocellular carcinomas and combined hepatocellular adenomas and carcinomas, and increased incidences of bronchioalveolar adenomas and adenocarcinomas of the lung in females at 50, 200 and 600 ppm (but not 500 ppm) relative to their controls.
• Page 24. In a 2-generation study (MRID 00157225), liquified bifenthrin (88.35% ai) mixed with acetone was administered in the diet to TAC(SD)fBR rats (25/sex/dose) at dose levels of 0, 30, 60, or 100 ppm as FMC 54800 technical (approximately equivalent to 0, 1.5, 3.0 and 5.0 mg/kg/day)... In the high-dose P generation females, there was a statistically significant increase in absolute and relative brain weights... In the 100 ppm group F1b female progeny, absolute adrenal and heart weights were statistically elevated compared to control values. Significantly elevated absolute ovary and ovary/brain weights were also observed in these animals.
|
| August 1, 2007 |
EPA-HQ-OPP-2007-0471 |
IR-4.
Pesticide
Petitions PPs 6E7125, 6E7126, 6E7127 and 6E7128. Proposal
to establish a
tolerance for residues of the insecticide bifenthrin in or
on food commodities
| Commodity |
PPM |
| pistachio |
0.05 |
| mayhaw |
1.4 |
vegetables, fruiting, group
8
This group includes
17 commodities.
chili, postharvest • eggplant • groundcherry
• pepino • pepper • pepper, bell
• pepper, nonbell • pepper, nonbell, sweet
• tomatillo • tomato • tomato, concentrated
products • tomato, dried pomace • tomato,
paste • tomato, puree • tomato, wet pomace
• vegetable, fruiting • vegetable, fruiting,
group
|
0.5 |
| peanut |
0.05 |
| soybean |
0.2 |
vegetable, root, except sugar beet
and garden beet, subgroup 1B
This
subgroup includes 19 commodities.
beet, garden • burdock, edible • carrot
• carrot culls • celeriac • chervil,
turnip rooted • chicory root • ginseng
• horseradish • parsley, turnip rooted
• parsnip • radish • radish, oriental
• rutabaga • salsify • salsify,
black • salsify, spanish • skirret •
turnip
|
0.07 |
| beet, garden, roots |
0.45 |
| beet, garden, tops |
15 |
There is a practical analytical method for
detecting and measuring levels of bifenthrin in or on food
with a limit of detection that allows monitoring of food with
residues at or above the levels set in these tolerances gas
chromatography with electron capture detection (GC/ECD). |
| August 1, 2007 |
EPA-HQ-OPP-2007-0535 |
R-4.
Pesticide
Petition PP 7E7227. Proposal to establish a tolerance
for residues of the insecticide bifenthrin in or on food commodities:
| Commodity |
PPM |
bushberry subgroup
13-B
This subgroup includes
5 commodities.
blueberry • currant • elderberry •
gooseberry • huckleberry
|
2.0 |
| juneberry |
2.0 |
| lingonberry |
2.0 |
| salal |
2.0 |
| aronia berry |
2.0 |
| blueberry, lowbush |
2.0 |
| buffalo currant |
2.0 |
| chilean guava |
2.0 |
| European barberry |
2.0 |
| highbush cranberry |
2.0 |
| honeysuckle |
2.0 |
| jostaberry |
2.0 |
| native currant |
2.0 |
| sea buckthorn |
2.0 |
leafy petioles subgroup
4-B
This subgroup includes
8 commodities.
amaranth, leafy • cardoon • celery •
celery, chinese • celtuce • fennel, florence
• rhubarb • swiss chard
|
3.0 |
There is a practical analytical method for
detecting and measuring levels of bifenthrin in or on food
with a limit of detection that allows monitoring of food with
residues at or above the levels set in these tolerances GC/ECD. |
| February 28, 2007 |
EPA-HQ-OPP-2007-0005 |
Notice
of Receipt of Request to Voluntarily Cancel Certain Pesticide
Registrations.
| Registration No. |
Product Name |
Registrant |
| 000279-03135 |
Bistar T&O EC Insecticide |
FMC Corp. Agricultural Products Group
1735 Market St,
Philadelphia, PA 19103 |
|
| December 20, 2006 |
EPA-HQ-OPP-2006-0942 |
Extension
of Tolerances for Emergency Exemptions
This regulation extends time-limited tolerances on orchardgrass
for control of the orchardgrass billbug in Oregon.
This regulation extends time-limited tolerances for residues
of the insecticide bifenthrin in or on
-- orchardgrass, forage and orchardgrass,
hay at 0.05 ppm
for an additional 2-year period. These tolerances will expire
and are revoked on December 31, 2009. |
| August 25, 2006 |
EPA-HQ-OPP-2006-0659 |
Pesticide
Emergency Exemptions; Agency Decisions and State and Federal
Agency Crisis Declarations
• Oregon: EPA authorized
the use of bifenthrin on orchardgrass
grown for seed to control the orchardgrass billbug; April
21, 2006 to November 15, 2006.
• Louisiana: EPA authorized
the use of bifenthrin on sweet potato
to control soil beetles and the sweet potato weevil; May 15,
2006 to November 30, 2006. |
| August 11, 2006 |
EPA-HQ-OPP-2006-0366 |
IR-4.
Pesticide
tolerance. FINAL
RULE.
-- Coriander, dried leaves at 25 ppm
-- Coriander, leaves at.6.0 ppm
-- Coriander, seed at 5.0 ppm
-- Okra at 0.50 ppm
--
Turnip, greens at 3.5 ppm
--
Pea and bean, dried shelled, expect soybean, subgroup
6C at 0.15 ppm
This
subgroup includes 27 commodities.
bean, adzuki • bean, broad dry • bean, dry •
bean, kidney • bean, lablab • bean, lima dry
• bean, moth • bean, mung • bean, navy
• bean, pink • bean, pinto • bean, rice
• bean, tepary • bean, urd • catjang •
chickpea • cowpea • guar • lentil •
lupin, grain • lupin, sweet • pea, blackeyed
• pea, crowder • pea, field • pea, field
seed • pea, pigeon • pea, southern
-- Brassica, leafy greens, subgroup
5B ...... 3.5 ppm
This
subgroup includes 8 commodities:
broccoli raab • cabbage, chinese bok choy •
collards • kale • mizuna • mustard greens
• mustard spinach • rape greens
--
Vegetable, tuberous and corm, subgroup
1C ...... 0.05 ppm
This subgroup includes 22
commodities: arracacha • arrowroot
• artichoke, chinese • artichoke, jerusalem
• canna, edible • cassava • chayote root
• chufa • dasheen • ginger • leren
• potato • potato culls • potato granules
flakes • potato peel, wet • potato processed
potato waste • potato, specialty • sweet potato
• tanier • turmeric • yam bean •
yam, true
|
| June 28, 2006 |
EPA-HQ-OPP-2006-0084 |
Notice
of Receipt of Requests to Voluntarily Cancel Certain Pesticide
Registrations.
| Registration No. |
Product Name |
Registrant |
| 001381-00193 |
Tundra EC |
Agriliance, LLC,
PO Box 64089,
St. Paul, MN 551640089 |
|
| June 7, 2006 |
EPA-HQ-OPP- 2006-0387 |
Pesticide
Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations.
-- Mississippi: EPA authorized
the use of bifenthrin on sweet potatoes
to control beetle complex; March 27, 2006 to September 30,
2006.
-- North Carolina: EPA authorized
the use of bifenthrin on sweet potatoes
to control beetle complex; March 27, 2006 to October 31, 2006.
|
| May 10, 2006 |
EPA-HQ-OPP-
2006-0366 |
IR-4.
Pesticide
petitions: PP 2E6451, 3E6882, 2E6492, 2E6423, and 4E6843.
in and/or on:
-- cilantro at 5.0 ppm (4E6843).
-- turnip greens at 3.0 ppm (2E6451)
-- okra at 0.5 ppm (2E2649)
-- leafy brassica greens, subgroup
5B at 3.0 ppm (2E6451)
This subgroup includes 8
commodities.
broccoli raab • cabbage, chinese bok choy •
collards • kale • mizuna • mustard greens
• mustard spinach • rape greens
-- tuberous and corm vegetables, subgroup
1C at 0.1 ppm (3E2688)
This subgroup includes 22
commodities.
arracacha • arrowroot • artichoke, chinese •
artichoke, jerusalem • canna, edible • cassava
• chayote root • chufa • dasheen •
ginger • leren • potato • potato culls
• potato granules flakes • potato peel, wet
• potato processed potato waste • potato, specialty
• sweet potato • tanier • turmeric •
yam bean • yam, true
-- dried shelled pea and bean (except soybean),
subgroup 6C at 0.1 ppm (2E6423)
This subgroup includes 27
commodities.
bean, adzuki • bean, broad dry • bean, dry •
bean, kidney • bean, lablab • bean, lima dry
• bean, moth • bean, mung • bean, navy
• bean, pink • bean, pinto • bean, rice
• bean, tepary • bean, urd • catjang •
chickpea • cowpea • guar • lentil •
lupin, grain • lupin, sweet • pea, blackeyed
• pea, crowder • pea, field • pea, field
seed • pea, pigeon • pea, southern
|
| Nov
16, 2005 |
OPP-2005-0277 |
Pesticide
Emergency Exemptions.
•
Oregon. EPA authorized the use of bifenthrin on orchardgrass
to control the orchardgrass billbug; July 8, 2005 to November
15, 2005. |
| August
31, 2005 |
OPP-2005-0223 |
Pesticide
Emergency Exemptions:
•
Louisiana.
Specific: EPA authorized the use of bifenthrin
on sweet potato to control
soil beetle complex; April 29, 2005 to November 30, 2005.
Contact: (Andrea Conrath).
• Mississipi. EPA authorized
the use of bifenthrin on sweet
potato to control soil beetle complex; April 29, 2005
to September 30, 2005. Contact: (Andrea Conrath).
• North Carolina. Specific:
EPA authorized the use of bifenthrin
on sweet potato to control beetle
complex; April 1, 2005 to September 30, 2005. Contact: (Libby
Pemberton). |
| August
3, 2005 |
OPP-2005-0201 |
Cancellation
of Pesticides for Non-payment of Year 2005 Registration Maintenance
Fees.
| Section
24(c) Registrations canceled for non-payment of the
2005
maintenance fee are shown in the following Table 1:
Table
1.--Section 24(c) Registrations Canceled for Non-Payment
of Maintenance Fee |
|
SLN no. |
Product
Name |
| 000279
WY-97-0004 |
Capture
2 EC Insecticide/miticide |
|
Section 3 registrations canceled for non-payment of
the 2005
maintenance fee are shown in the following table 2:
Table
2.--Section 3 Registrations Canceled for Non-Payment
of
Maintenance Fee |
|
Registration no. |
Product
Name |
| 074627-00003 |
Nab
2.4 ME Insecticide |
|
| Feb
10, 2005 |
OPP-2005-0025 |
Removal
of Expired Time-limited Tolerances for Emergency Exemptions.
FINAL
RULE.
• 3. Bifenthrin. Time-limited tolerances
for peanut and potato are being
removed from Sec. 180.442 because they expired on or
before December 31, 2003. |
| Dec
22, 2004 |
OPP-2004-0350 |
Pesticide
Emergency Exemptions. •
North Carolina
- EPA authorized the use of bifenthrin
on sweet potatoes to control beetle
complex; August 12, 2004 to September 30, 2004. Contact: (Libby
Pemberton) |
| Nov
10, 2004 |
OPP-2004-0232 |
Four
Pesticide Emergency Exemptions.
• Arkansas
-
EPA authorized the use of bifenthrin
on sweet potatoes to control
beetle complex; April 29, 2004 to November 30, 2004. Contact:
(Stacey Groce)
• Louisiana
- EPA authorized the use of bifenthrin
on sweet potatoes
to control beetle complex; May 20, 2004 to November 30, 2004.
Contact: (Stacey Groce).
•
Mississippi
- EPA authorized the use of bifenthrin
on sweet potatoes to control
beetle complex; April 29, 2004 to September 30, 2004. Contact:
(Stacey Groce).
• North Carolina - On June
2, 2004, for the use of bifenthrin on sweet
potatoes to control wireworm. This program is expected
to end on September 30, 2004. Contact: (Libby Pemberton). |
| Oct
27, 2004 |
OPP-2004-0338 |
Cancellation
of Pesticides for Non-payment of Year 2004 Registration Maintenance
Fees.
| Table
1.--Section 24(c) Registrations Canceled for Non-Payment
of Maintenance Fee |
| Name
of Pesticide |
Product
Name |
Registrant |
SLN
No. |
| Bifenthrin |
Biflex
TC Termiticide |
FMC
Corp Agricultural Products Group |
000279
LA-96-0013 |
| Bifenthrin |
Biflex
TC Termiticide |
FMC
Corp Agricultural Products Group |
000279
MS-97-0002 |
|
| May
24, 2004 |
OPP-2004-0136 |
Extension
of Tolerances for Emergency Exemptions. FINAL RULE.
EPA
has authorized under FIFRA section 18 the use of bifenthrin
on orchardgrass, forage and orchardgrass, hay for control of
orchardgrass billbug in Oregon. This regulation extends
time-limited tolerances for residues of the insecticide bifenthrin
in or on
orchardgrass, forage and orchardgrass, hay at 0.05 ppm for
an additional 3-year period. These tolerances
will expire and are revoked on June 30, 2007. Time-limited tolerances
were originally published in the Federal Register of July 26,
2002. |
| May
5, 2004 |
OPP-2004-0116 |
Pesticide
Emergency Exemptions.
Oregon
- EPA authorized the use of bifenthrin on orchardgrass
grown for seed to control the orchardgrass billbug; March
30, 2004 to November 15, 2004. |
| March
4, 2004 |
ORD-2003-
0011 |
Announcement:
Longitudinal Study of Young Children's Exposures in their
Homes to Selected Pesticides, Phthalates, Brominated Flame
Retardants, and Perfluorinated Chemicals
(A Children's Environmental Exposure Research Study--CHEERS).
Abstract: The U.S. EPA's Office of Research and Development's
National Exposure Research Laboratory proposes to conduct
a two-year longitudinal field measurement study of young children's
(aged 0 to 3 years) potential exposures to current-use pesticides
and selected phthalates, polybrominated diphenyl ethers, and
perfluorinated compounds that may be found in residential
environments. The study will be conducted in Duval County,
Jacksonville, Florida over a two-year period from 2004 to
2006. Sixty young children will be recruited into this study
in two cohorts: (1) infants recruited into the study soon
after birth, and, (2) children recruited into the study at
approximately 12 months of age. ...
Part
A: Supporting Statement
- EPA ICR Number: 2126.01 - 61 pages
From Table 2:
• Of 16 pesticides included in this study, 4 are
fluorinated:
Bifenthrin, Fipronil, lamda-Cyhalothrin,
and Cyfluthrin I, II, III, IV, total
•
Perfluorinated chemicals:
Perfluorooctanoic acid (PFOA) and Perfluorooctane sulfonate
(PFOS)
From
Table 3: List of chemicals to be analyzed in biological
media:
• one is fluorinated: 4-fluoro-3-phenoxybenzoic
acid
• Perfluorooctanoic acid/Perfluorooctane sulfonate |
|
| Jan
14, 2004 |
OPP-2003-0402 |
Extension
of Tolerances for Emergency Exemptions. FINAL RULE.
EPA has authorized under FIFRA section 18 the use of bifenthrin
on sweet potatoes for control of soil beetles and weevils in
Louisiana and Mississippi. This
regulation extends a time-limited tolerance for residues of
the insecticide bifenthrin in or on
sweet potato, roots at 0.05 ppm for an
additional 2-year period. This tolerance will expire and is
revoked on December 31, 2005. A time-limited tolerance
was originally published in the Federal
Register of September 27, 2001, subsequently corrected by
a technical amendment published in the Federal
Register of September 3, 2003. |
| Nov
26, 2003 |
OPP-2003-0358 |
3
Approved Requests for Pesticide Emergency Exemptions.
-- Louisiana Department of Agriculture
and Forestry. EPA authorized the use of bifenthrin on sweet
potatoes to control soil beetles, and sweet potato weevil;
May 19, 2003 to November 30, 2003.
-- Mississippi
Department of Agriculture and Commerce. EPA authorized
the use of bifenthrin on sweet potatoes
to control soil beetles; May 19, 2003 to September 30, 2003.
-- Oregon Department of Agriculture.
EPA authorized the use of bifenthrin on
orchardgrass grown for seed
to control the orchardgrass billbug; April 4, 2003 to November
15, 2003. |
| Sept
3, 2003 |
OPP-2003-0288 |
Pesticide
Tolerance for Emergency Exemption; Technical Amendment.
Final Rule. EPA
issued a final rule in the Federal Register of September 27,
2001 to establish a time-limited tolerance for residues of bifenthrin
in or on sweet potato at 0.05 ppm. This action was in response
to EPA's granting of an emergency exemption under section 18
of the Federal Insecticide, Fungicide, and Rodenticide Act authorizing
use of the pesticide on sweet potato. The
amendment to establish the tolerance for bifenthrin inadvertently
added the tolerance for ``sweet potato'' to 40 CFR 180.442(a).
However, 40 CFR 180.442(a) is not designated
for section 18 emergency exemptions; consequently, the entry
for sweet potato could not be added to Sec. 180.442(a) by the
Office of the Federal Register. This technical amendment
is being issued to correctly add the tolerance for sweet potato
to the table in Sec. 180.442(b), which is designated for time-limited
tolerances associated with section 18 emergency exemptions.
-- EPA is also changing the commodity
term ``sweet potato'' to read ``sweet potato, roots.'' |
| April
30, 2003 |
OPP-2002-0358 |
FMC;
IR-4. New
Pesticide Tolerances. FINAL RULE. This regulation
establishes tolerances for residues of bifenthrin in or on
| Commodity |
Final
Rule
Parts per million |
Proposed
Tolerances |
Pesticide
Petition |
Date
Petition published in FR |
Note
from FAN - Original Petitioner |
| Food
products in food handling establishments |
0.05 |
0.01
|
PP
2F6390 |
Feb
15, 2002 |
FMC
- Feb 15, 2002 |
| Almond,
hulls |
2.0 |
2
|
PP
6F3454 |
Feb
15, 2002 |
FMC
- Feb 15, 2002 |
| Banana
- Imported |
0.1 |
0.1 |
PP
0E6216 |
Feb
14, 2001 |
FMC
- Feb 14, 2001 |
| Carambola
(starfruit) - imported |
Determined
by EPA to be insufficient to support the proposed tolerances;
subsequently withdrawn by the Taipei Economic and Cultural
Representative Office. |
1.0 |
PP
1E6234 |
Feb
15, 2002 |
The
Taipei Economic and Cultural Representative
Office in the United States - Feb 15, 2002 |
| Fruit,
citrus, group 10 |
0.05 |
0.05 |
PP
1F6266 |
Feb
14, 2001 |
FMC
- Feb 14, 2001 |
| EPA
is deleting time-limited tolerances established for residues
of bifenthrin in or on citrus, dried pulp, at 0.3 ppm,
citrus oil at 0.3 ppm and citrus, whole fruit, at 0.05
ppm in connection with section 18 emergency exemptions
granted by EPA. With the establishment of the citrus fruit
group tolerance (PP 1F6266), these tolerances are no longer
needed. |
| Herb
subgroup 19A |
0.05 |
0.05 |
PP
0E6157 |
Feb
15, 2002 |
IR-4
- Feb 15, 2002 |
Herb
subgroup 19A includes:
(allspice; angelica; anise hyssop,
leaves; anise, seed; anise, star; annatto, seed; basil,
dried leaves; basil, fresh leaves; borage, dried leaves;
borage, fresh leaves ;burnet, leaves; camomile; caper,
buds; caraway, black, seed caraway, seed; cardamom, seed;
cardamon amomum, seed; cassia; catnip; celery, seed; chervil,
dried leaves; chive, chinese; chive, leaves; cinnamon;
clary, dried leaves; clary, fresh leaves; clove; coriander,
leaves; coriander, seed; costmary, dried leaves; costmary,
fresh leaves; culantro, leaves; culantro, seed; cumin;
curry, dried leaves; curry, fresh leaves; dill, seed;
dillweed, dried leaves; dillweed, fresh leaves; fennel,
florence, seed; fennel, seed; fenugreek, seed; grains
of paradise, seed; horehound, leaves; hyssop, tops; juniper
berry; lavender; lemongrass, leaves; lovage, leaves; lovage,
seed; mace; marjoram, tops; mustard, seed; nasturtium,
leaves; nutmeg; parsley, dried leave;s pennyroyal, leaves;
pepper, black pepper;, white poppy, seed; rosemary, dried
leaves; rosemary, fresh leaves; rue, dried leaves; rue,
fresh leaves; saffron, stigma; sage, dried leaves; sage,
fresh leaves; savory, summer, dried leaves; savory, summer,
fresh leaves; savory, winter, dried leaves; savory, winter,
fresh leaves; sweet bay, dried leaves; tansy, dried leaves
tansy, fresh leaves; tarragon, dried leaves; tarragon,
fresh leaves; thyme, dried leaves; thyme, fresh leaves;
vanilla; wintergreen, dried leaves; wintergreen, fresh
leaves; woodruff, dried leaves; woodruff, fresh leaves;
wormwood, dried leaves; wormwood, fresh leaves) |
Leaf
petioles subgroup (4B) (includes
cardoon, celery, Chinese celery, celtuce, Florence fennel,
rhubarb, Swiss chard)
|
Determined
by EPA to be insufficient to support the proposed tolerances;
cannot be established until adequate residue chemistry
data are submitted and reviewed. |
2.0 |
PP
6E4630 |
Feb
15, 2002 |
IR-4
- Feb 15, 2002 |
Nut,
tree, group 14
(almond; almond, hulls; beechnut;
butternut; cashew; chestnut; chinquapin; filbert; nut
brazil; nut, hickory; nut, macadamia; pecan; pistachio;
walnut) |
0.05 |
0.05
|
PP
6F3454 |
Feb
15, 2002 |
FMC
- Feb 15, 2002 |
| Pear |
0.5 |
1.0 |
PP
6F3454 |
Feb
15, 2002 |
FMC
- Feb 15, 2002 |
| Spinach |
0.2 |
0.2 |
PP
2E6402 |
Feb
15, 2002 |
IR-4
- Feb 15, 2002 |
| Tomato |
0.15 |
0.15 |
PP 1E6330 |
Feb
15, 2002 |
IR-4
- Feb 15, 2002 |
-- Category
C (possible human) carcinogen, primarily
on the basis of the mouse carcinogenicity study in which the
high-dose males (81.3 mg/kg/day) showed a
highly significant increased incidence of urinary bladder
tumors. Other findings in the mouse study included
a dose-related trend of increased combined incidences of adenoma
and adenocarcinoma of the liver (males only), and increased
incidences of bronchioalveolar
adenomas and adenocarcinomas of the lung in females at
some, but not all, doses relative to their controls.
-- Acute Neurotoxicity Study in Rats. LOAEL = 70.3 mg/kg/day.
based on observations of mortality (females
only), clinical and functional operational battery (FOB) findings
and differences in motor activity.
-- 1-Year Oral Study in Dogs. LOAEL
= 2.7 mg/kg/day based on observations of
increased incidence of tremors in both sexes.
-- 90-Day Oral Study in Dogs. LOAEL = 4.42 mg ai/kg/ day based
on observations of increased incidence
of tremors in both sexes.
-- 21-Day Dermal Study in Rats. LOAEL
= 93 mg/kg/day based on observations of clinical signs (staggered
gait and exaggerated hindlimb flexion). |
| April
16, 2003 |
OPP-2003-0116 |
Requests to voluntarily
cancel certain pesticide registrations. EPA is issuing
a notice of receipt of request by registrants to voluntarily
cancel certain pesticide registrations. Unless a request is
withdrawn by October 13, 2003, or May 16, 2003 for EPA Registration
Numbers: 003008-00021, 075341-00001, and 075341-00007,
orders will be issued canceling these registrations.
| Product |
Registration
Number |
Company
Name and Address |
| Biflex
TC Termiticide |
000279
AZ-95-0004 |
FMC
Corp.Agricultural Products Group,
1735 Market St, Philadelphia, PA 19103. |
|
| Feb
24, 2003 |
OPP-2003-0033 |
Pesticide
Emergency Exemption.
Texas.
Specific: EPA authorized the use of bifenthrin
on citrus to control weevils;
November 22, 2002 to November 22, 2003. |
| Jan
16, 2003 |
OPP-2002-0336
|
Extension
of Tolerances for Emergency Exemptions. EPA
has authorized under FIFRA section 18 the use of bifenthrin
on citrus for control of weevils in Texas and Florida. This
regulation extends time-limited tolerances for residues of
the insecticide bifenthrin in
or on citrus, dried pulp and citrus, oil at 0.3 ppm for an
additional 2-year period. This tolerance
will expire and is revoked on December 31, 2004. A time- limited
tolerance was originally published in the Federal Register
of December 16, 1998 (63 FR 69200) (FRL-6048-1). |
| Nov
27, 2002 |
OPP-2002-0313 |
EPA
approved the use of Bifenthrin for 5 Emergency Exemptions.
--
Kansas: EPA authorized the use of bifenthrin
on sorghum grown for seed to control banks grass mite; August
16, 2002 to September 30, 2002.
-- Louisiana: Crisis: On May
3, 2002, for the use of bifenthrin on sweet potatoes to control
soil beetles and sweet potato weevils. This program is expected
to end on November 30, 2002.
-- Louisiana: EPA authorized
the use of bifenthrin on sweet potatoes to control soil beetles
and sweet potato weevils; July 19, 2002 to November 30, 2002.
-- Mississippi: EPA authorized
the use of bifenthrin on sweet potatoes to control soil beetles;
July 19, 2002 to September 30, 2002.
-- Texas: EPA authorized the
use of bifenthrin on sorghum grown for seed to control banks
grass mite; August 16, 2002 to August 16, 2003. |
| July
26, 2002 |
OPP-2002-0145 |
Pesticide
Tolerances for Emergency Exemptions for time-limited tolerances
for residues of bifenthrin in or on orchardgrass hay and forage
at 0.05 ppm. Final Rule. The tolerance will expire and is
revoked on June 30, 2004.
Oregon produces nearly all of the nation's orchardgrass seed,
which is primarily used as a high protein pasture grass. No
orchardgrass residue data were submitted for this request.
The proposed use rate of bifenthrin for orchardgrass is approximately
the same as that registered for use on alfalfa grown for seed.
Therefore, the data from alfalfa was translated to orchardgrass
for this section 18 use. The established tolerances for meat
and milk commodities are adequate to cover any residues which
may result from this section 18 use... EPA concluded that
exposure to bifenthrin from food will utilize 60% of the acute
population adjusted dose (aPAD) for the U.S. population, 40%
for females 13 years and older, 75% for all infants 1 year
old, and 99.7% of the aPAD for
children 1 to 6 years old. In addition, despite the potential
for acute dietary exposure to bifenthrin in drinking water,
after calculating drinking water levels of concern (DWLOCs)
and comparing them to conservative model estimated environmental
concentrations (EECs) of bifenthrin in surface and ground
water, EPA does not expect the aggregate exposure to exceed
100% of the aPAD...
Bifenthrin has been classified as a Group C chemical (possible
human carcinogen) based upon urinary bladder tumors in mice.
Conditions. One application may be made. A maximum of 0.10
pound of active ingredient may be applied per acre using ground
equipment. Bifenthrin is not to be applied within 30 days
of grazing, feeding, or harvesting (cutting) forage or hay.
|
| May
17, 2002 |
OPP-2002-0037 |
Revocation
of Expired Time Limited Tolerances. Final Rule. Time-limited
tolerances for broccoli; cabbage; canola seed; cauliflower;
grapes; raspberries; and cucurbit vegetables are being removed
from 40 CFR 180.442 because they expired on or before December
31, 2001. |
| Feb
15, 2002 |
PF-1069 |
- Seven
Pesticide Petitions to establish new tolerances:
- FMC:
PP 2F6390 proposes a tolerance in or on food products in
food handling establishments at 0.01 ppm.
- FMC:
PP 6F3454 proposes a tolerance in or on the raw agricultural
commodity pears at 1.0 ppm, in or on almond hulls at 2 ppm
and in or on the tree nuts crop group at 0.05 ppm.
- IR-4:
PP 6E4630 proposes a tolerance for the leaf petioles subgroup
(4B) (includes cardoon, celery, Chinese celery, celtuce,
Florence fennel, rhubarb, Swiss chard) at 2.0 ppm.
- IR-4:
PP 0E6157 proposes a tolerance for the herb subgroup (19A)
at 0.05 ppm.
- IR-4:
PP 1E6330 proposes a tolerance for tomato at 0.15 ppm.
- IR-4:
PP 2E6402 proposes a tolerance for spinach at 0.2 ppm.
- Taipei
Economic and Cultural Representative Office in the U.S.:
1E6234 request to establish an import tolerance for residues
of bifenthrin in or on carambola (starfruit) at 1.0 ppm.
Docket control number PF-1069
|
| Feb
13, 2002 |
OPP-181085 |
- Emergency
Exemptions:
- Texas:
Crisis: On March 21, 2001, for the use of bifenthrin on
citrus to control weevils. This program is expected to end
on November 14, 2002.
- Texas:
Specific: EPA authorized the use of bifenthrin on citrus
to control weevils; November 14, 2001 to November 14, 2002.
|
| Dec
14, 2001 |
OPP-301194 |
Extension
of time-limited tolerance for residues - FINAL
RULE:
in or on peanuts, nutmeats at 0.05 ppm for an additional 2-year
period. This tolerance will expire on December 31, 2003. Objections
and requests for hearings, identified by docket control number
OPP-301194, must be received by EPA on or before January 14,
2002. |
| Nov
14, 2001 |
OPP-181082 |
- 3
Pesticide Emergency Exemptions: EPA authorized use in:
- Florida:
on citrus to control diaprepes root weevil; March 2, 2001
to March 2, 2002.
- Oklahoma:
on peanuts to control spider mites; July 15, 2001 to October
30, 2001.
- Texas:
on sorghum grown for seed to control Banks grass mite; August
1, 2001 to August 1, 2002.
|
| Oct
3, 2001 |
na |
- Public
Report on Minor Use Pesticides; Notice of Availability.
- "Minor
uses of pesticides are those for which the total U.S.acreage
for a particular crop is less than 300,000 acres or those
for which the use does not provide sufficient economic incentive
to support its registration." - see Report
cited in the Federal Register which includes the following
fluorinated pesticides:
- Bifenthrin
Insecticide (Trade names Capture, Brigade, Talstar, Biflex)
- Diflubenzuron
Insect Growth Regulator Insecticide (Trade name Dimilin)
- Fludioxonil
Fungicide (Trade names Maxim, Medallion)
|
| Sept
27, 2001 |
OPP-301169 |
|
| Feb
14, 2001 |
PF-998 |
FMC
- Pesticide
Tolerance Petition for residues in or on bananas at 0.1 ppm. |
| Dec
20, 2000 |
OPP-181078 |
Pesticide
Emergency Exemptions for use on citrus in FL, on seed sorghum
in KS and TX, on peanuts in OK., potatoes and raspberries in
OR and WA |
| Sept
27, 2000 |
OPP-301047 |
Pesticide
Time-Limited Tolerances for Emergency Exemptions for potato
at 0.05 ppm. - FINAL
RULE.
|
| Dec
22, 1999 |
PF-903 |
|
| June
30, 1999 |
OPP-300888 |
Pesticide
Tolerances for various AG commodities (including, in or on Cabbage
at 4 ppm)- FINAL
RULE. |
| May
26, 1999 |
na |
FMC
- Request
to Voluntarily Cancel the product: Talstar 10WP Insecticide/miticide.
|
| May
19, 1999 |
PF-873 |
- IR-4
* - Filing
of Seven Pesticide Petitions for tolerances of residues
in or on the raw agricultural commodities.
- PP
6E4629 proposes the establishment of a tolerance for artichoke
at 1 ppm.
- PP
6E4760 proposes the establishment of a tolerance for crop
group 9 cucurbit vegetables at 0.4 ppm.
- PP
8E4993 proposes the establishment of a tolerance for crop
subgroup 6B edible-podded legume vegetables at 0.2 ppm.
- PP
8E5009 proposes the establishment of a tolerance for eggplant
at 0.05 ppm.
- PP
9E5084 proposes the establishment of a tolerance for rapeseed
including, canola and crambe seed, at 0.05 ppm.
- PP
9E5069 proposes the establishment of a tolerance for crop
subgroup 5A Head and Stem Brassica, excluding cabbage, at
0.6 ppm and cabbage at 4.0 ppm.
- PP
9E5064 proposes the establishment of a tolerance for crop
subgroup 6B, succulent shelled peas and beans at 0.5 ppm.
|
| May
19, 1999 |
PF-873 |
FMC
- Pesticide
Tolerance Petition for residues in or on the raw agricultural
commodity sweet corn at 0.05 ppm; and proposal to amend the
existing tolerance for corn forage from 2.0 to 3.0 ppm. |
| April
28, 1999 |
OPP-300852 |
Extension
of Tolerance for Emergency Exemptions for residues of the insecticide
and its metabolites in or on cucurbits at 1 ppm for an additional
18 month period. -
FINAL RULE.
This tolerance will expire and is revoked on October 31, 2000.
|
| March
24, 1999 |
na |
Request
to voluntarily cancel 2 pesticide registrations: Talstar
Granular, EPA Reg. No. 000279 AZ-93-0017; and Talstar 10WP Insecticide/miticide,
EPA Reg. No. 000279 AZ-93-0018. |
| March
10, 1999 |
OPP-181067 |
Application
for Emergency Exemption. EPA has received a specific exemption
request from the Washington Department
of Agriculture to use the pesticide bifenthrin (CAS 8657-04-3
cis and 83322-02-5 trans), formulated as Brigade WSB, to treat
up to 8,500 acres of raspberries to control weevils. This is
the seventh year this use has been requested, and it has been
allowed under section 18 for the past 6 years. Since this request
proposes a use which has been requested or granted in any 3
previous years, and a complete application for registration
and petition for tolerance has not yet been submitted to the
Agency, EPA is soliciting public comment before making the decision
whether or not to grant the exemption. |
| Dec
16, 1998 |
OPP-300762 |
Pesticide
Tolerances for Emergency Exemptions for residues of in or on
CITRUS: whole fruit at 0.05 ppm; oil and dried pulp at 0.3 ppm.
- FINAL RULE.
These
tolerances will expire and are revoked on December 31, 2000. |
| Oct
7, 1998 |
PF-831 |
FMC
- Pesticide
Tolerance Petition for residues in or on the raw agricultural
commodity corn, grain (sweet) at 0.05 ppm and corn, forage
at 3.0 ppm. |
| July
10, 1998 |
OPP-300677 |
Pesticide
Tolerances for Emergency Exemptions. -
FINAL RULE.
This regulation establishes a time-limited tolerance for residues
of bifenthrin in or on raspberries at 3 ppm. |
| April
1, 1998 |
OPP-300630 |
Extension
of Tolerance for Emergency Exemptions for residues of the insecticide
and its metabolites in or on cucurbits at 1.0 ppm for an additional
one-year period.- FINAL
RULE.
This tolerance will expire and are revoked on April 30, 1999.
|
| March
25, 1998 |
OPP-181057 |
Application
for Emergency Exemption. EPA has received a specific exemption
request from the Washington Department
of Agriculture to use the pesticide bifenthrin (CAS 8657-04-3
cis and 83322-02-5 trans), formulated as Brigade WSB, to treat
up to 9,500 acres of raspberries to control weevils. This is
the sixth year this use has been requested, and it has been
allowed under section 18 for the past 5 years. If all 9,500
acres are treated at this maximum rate, this could potentially
result in a total use of 1,900 lb. of active ingredient. |
| Feb
9, 1998 |
na |
Technical
Amendments to Pesticide Tolerance; Correction of Effective Date
Under Congressional Review Act (CRA). -
FINAL RULE. On June 12, 1996 (61 FR 29676), the
EPA published in the Federal Register a final rule establishing
a tolerance for residues of the pesticide bifenthrin in or on
the raw agricultural commodity strawberries, which established
an effective date of June 12, 1996. This document corrects the
effective date of the rule to February 9, 1998 to be consistent
with sections 801 and 808 of the CRA. |
| Jan
14, 1998 |
OPP-300593 |
Pesticide
Tolerances for Emergency Exemptions. -
FINAL RULE.
This regulation establishes a time-limited tolerance for residues
of bifenthrin in or on cabbage at 2 ppm. The tolerance will
expire and is revoked on December 31, 1998. |
| Jan
9, 1998 |
OPP-300600 |
Extension
of Tolerance for Emergency Exemptions. -
FINAL RULE. This rule extends a time-limited
tolerance for residues of the insecticide bifenthrin in or on
broccoli and cauliflower at 0.1 and 0.05 ppm, respectively,
for an additional 1-year period, to January 31, 1999. |
| Nov
26, 1997 |
OPP-300579 |
Pesticide
Tolerances for various AG commodities (including dried hops
at 10 ppm; corn fooder at 5 ppm. FINAL
RULE. |
| Oct
29, 1997 |
OPP-181049 |
Request
for Emergency Exemption for Bifenthrin, formulated as Capture
2EC, to treat up to 22,000 acres of broccoli, cauliflower,
cabbage, and rapini; and 40,000 acres of lettuce, to control
silverleaf whitefly. Specific exemption request from the California
Department of Pesticide Regulations |
| Oct
3, 1997 - Final |
na |
Cut
Roses. Exception Decisions to Early Entry Prohibition, Worker
Protection Standard; Technical Amendment. -
FINAL RULE.
See also Federal Register of Oct 30, 1996 below. |
| Oct
3, 1997 -Proposed |
OPP-250121 |
Pesticide
Worker Protection Standard; Administrative Exception for Cut-Rose
Hand Harvesting; Administrative Decision. Proposed Rule. |
| Sept
25, 1997 |
PF-767 |
FMC
- Filing
of Pesticide Petition to remove limitations on tolerances
in or on cottonseed and grain corn at 0.5 ppm, dried hops
at 10 ppm; and strawberries at 3.0 ppm. |
| Sept
5, 1997 |
OPP-300543 |
Pesticide
Tolerances for Emergency Exemptions. -
FINAL RULE.
This regulation establishes a time-limited tolerance for residues
of bifenthrin in or on canola seed at 0.5 ppm. The tolerance
will expire and is revoked on September 30, 1998. |
| August
4, 1997 |
OPP-300523 |
Pesticides
Subject to Tolerance Reassessment. |
| June
6, 1997 |
OPP-300495 |
Pesticide
Tolerances for Emergency Exemptions. -
FINAL RULE.
This regulation establishes time-limited tolerances for residues
of the pesticide bifenthrin in or on the raw agricultural commodity
crop group, cucurbits: Broccoli at 0.1 ppm, Cauliflower at 0.05
ppm; and cucurbits (Crop Group 9 - cucumbers, melons, and squash)
at 1 ppm; and in or on the raw agricultural commodity raspberries
at 3 ppm in California, Arizona, and Texas; and use of bifenthrin
on raspberries in Oregon and Washington. These tolerances will
expire and are revoked on April 30, 1998 (cucurbits) and September
30, 1997 (raspberries). |
| March
5, 1997 |
OPP-181034 |
Application
for Emergency Exemption. EPA has received a specific exemption
request from the Washington Department of Agriculture (hereafter
referred to as the ``Applicant'') to use the pesticide bifenthrin
(CAS 82657-04-3 cis and 83322-02-5 trans), formulated as Brigade
WSB, to treat up to 9,500 acres of raspberries to control weevils.
This is the fifth year this use has been requested, and it has
been allowed under section 18 for the past 4 years. Since this
request proposes a use which has been requested or granted in
any 3 previous years, and a complete application for registration
and petition for tolerance has not yet been submitted to the
Agency, EPA is soliciting public comment. |
| Feb
12, 1997 |
OPP-300452 |
Pesticide
Tolerances for Emergency Exemptions. -
FINAL RULE.
This regulation establishes a time-limited tolerance for combined
residues of the insecticide bifenthrin in or on the raw agricultural
commodities broccoli at 0.1 ppm and cauliflower at 0.05 ppm.
These tolerances will expire and be revoked automatically without
further action by EPA on January 31, 1998. |
| Oct
30, 1996 |
na |
Emergency
Exemption for use on canola in MT. |
| Oct
30, 1996 |
OPP-300164I |
Cut-Roses;
Request for Exception to Worker Protection Standard's Prohibition
of Early Entry into Pesticide-Treated Areas to Harvest Roses
by Hand Cutting. |
| August
7, 1996 |
OPP-181021 |
Application
for Emergency Exemption on 62,000 acres in California. |
| June
19, 1996 |
na |
Emergency
Exemptions for use on canola in ID, OR, WA. |
| June
12, 1996 |
PP
5F4485/R2232 |
Pesticide
Tolerance of 3.0 ppm in and on strawberries. -
FINAL RULE. |
| April
24, 1996 |
na |
Emergency
Exemptions for use in California and Texas. |
| March
6, 1996 |
OPP-180993 |
Request
for Emergency Exemptions for use on 141,000 acres in AZ and
CA. |
| Feb
7, 1996 |
OPP-180987 |
Request
for Emergency Exemption for use on 62,000 acres in California.
|
| Dec
13, 1995 |
na |
Pesticide
Emergency Exemptions for use in AZ, ND, TX, VA. |
| Sept
20, 1995 |
na |
Emergency
Exemptions for use on canola in ID, OR, WA. |
| August
30, 1995 |
OPP-180979 |
Application
for Emergency Exemption for use on sweetpotato in Arizona. |
| July
26, 1995 |
na |
Emergency
Exemptions for use on strawberries in OR and WA, and raspberries
in OR. |
| July
19, 1995 |
na |
Emergency
Exemption for use on raspberries in WA. |
| June
15, 1995 |
PF-626;
FRL 4955-4 |
FMC
- Pesticide
Tolerance Petition of 3.0 ppm for strawberries and various
other AG commodities. |
| April
26, 1995 |
na |
Emergency
Exemptions for use on cucurbits in California and Texas. |
| Jan
12, 1995 |
na |
Request
for Emergency Exemptions for use on 200,000 acres of cucurbits
and 36,000 acres of sweetpotato. |
| Dec
28, 1994 |
na |
Emergency
Pesticide Use Exemptions for use in AZ, CA, TX. |
| Jan
12, 1994 |
OPPTS-400082 |
EPA's
proposal to add 41
fluorine and organofluorine chemicals to the Toxics Release
Inventory (TRI). See excerpt in box
above. Also available at http://www.epa.gov/tri/frnotices/59fr1788.htm |
| *
Interregional Project Number 4 (IR-4) Rutgers University,
New Brunswick, NJ, 08903-0231 |
|