Bifenthrin
CAS Nos. 82657-04-3 (Cis) - 83322-02-5 (Trans)
US Federal Register

 
 

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Adverse Effects
Abstracts

ACTIVITY: Insecticide, Acaricide (pyrethroid)

CAS Name: (2-methyl[1,1?-biphenyl]-3-yl)methyl 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate

Structure:

US Federal Register

Published Date Docket Identification Number Details
October 24, 2007 EPA-HQ-OPP-2007-0471

IR-4. Pesticide tolerance. FINAL RULE. Documents available with this Final Rule:

• Bifenthrin: Risk Assessment. Docket # EPA-HQ-OPP-2007-0471-0008
• Bifenthrin: Dietary Review. Docket # EPA-HQ-OPP-2007-0471-0007
• Bifenthrin: BEAD. Review Docket # EPA-HQ-OPP-2007-0471-0006

Commodity

PPM

FINAL RULE

PPM

Requested

Pesticide Petition Number
Beet, garden, roots

0.45 same PP 6E7126
Beet, garden, tops
15 same PP 6E7126
Grain, aspirated fractions 70 None  
Groundcherry 0.5 None  
Mayhaw
1.4 same PP 6E7125
Peanut 0.05 same PP 6E7127
Pepino 0.5 None  
Pistachio 0.05 same PP 6E7127
Radish, tops 4.5 None  
Soybean, hulls
0.50 None  
Soybean, refined oil
0.30 None  
Soybean, seed 0.2 0.2
for "Soybean"
PP 6E7128
Vegetable, root, subgroup 1B except sugar beet and garden beet
This subgroup includes 19 commodities: beet, garden • burdock, edible • carrot • carrot culls • celeriac • chervil, turnip rooted • chicory root • ginseng • horseradish • parsley, turnip rooted • parsnip • radish • radish, oriental • rutabaga • salsify • salsify, black • salsify, spanish • skirret • turnip
0.10 0.07 PP 6E7126

Cancer. Bifenthrin was classified as a group ``C'' (possible human carcinogen). The Agency concluded that the chronic risk and exposure assessment, making use of the cPAD, to be protective of any potential carcinogenic risk. Therefore, no separate exposure assessment was conducted pertaining to cancer risk.

Note on Petiton for Vegetable, fruiting, group 8. Tolerances are established for residues of bifenthrin per se at 0.05 ppm in/on eggplant, at 0.15 ppm in/on tomato, and at 0.5 ppm in/on bell and non-bell pepper. EPA has determined that a fruiting vegetables crop group tolerance for residues of bifenthrin per se is not appropriate for the following reasons:
Maximum residues in eggplant are more than a factor of five lower than the tolerance for tomatoes and the use pattern for tomato and tomatillo are different from the other members of the crop group in terms of the PHI, maximum seasonal use rate, number of applications, and interval between applications. However, EPA is establishing tolerances for residues in/on groundcherry and pepino at 0.50 ppm based on the 0.5 ppm tolerance for bell and non-bell pepper. As 40 CFR 180.1 indicates that a tolerance for residues in/on tomato applies to tomatillo, a tolerance for residues in/on tomatillo is not required.

From July 25, 2007, Health Risk Assessment;

• Page 3. Bifenthrin is a neurotoxic insecticide acting through direct contact and ingestion, having a slight repellent effect. The primary biological effects of bifenthrin and other pyrethroids on insects and vertebrates are inhibition of the voltage-gated Ca 2+ channels coupled with a stimulatory effect on the voltage-gated Na+ channels. All pyrethroids act as axonic poisons, affecting both the peripheral and central nervous systems, and share similar modes of action. Pyrethroids, including bifenthrin, stimulate repetitive action in the nervous system by binding to voltage-gated sodium channels, prolonging the sodium ion permeability during the excitatory phase of the action potential. This action leads to spontaneous depolarizations, augmented neurotransmitter secretion rate and neuromuscular block, which ultimately results in paralysis of the insect.

• Page 4. Bifenthrin produces characteristic pyrethroid neurotoxicity. Tremors have been observed in developmental toxicity studies in the rat and rabbit, a 2-generation rat reproduction toxicity study, subchronic toxicity studies in the rat and dog, acute and subchronic neurotoxicity rat studies, a 21-day toxicity dermal rat study, chronic oral toxicity studies in the rat and dog, and a mouse oncogenicity study. The subchronic and chronic oral toxicity studies in dogs and rats demonstrate neurotoxicological responses of similar magnitude. Staggered gait and exaggerated hindlimb flexion were noted in a 21-day dermal toxicity study in the rat. The neurotoxicity of bifenthrin has been supported by the results of acute and subchronic neurotoxicity studies in the rat. Functional observation battery (FOB) findings were observed in these neurotoxicity studies. FOB findings consisted of tremors, abnormal posture, splayed hindlimbs, staggered gait, altered activity, altered landing foot-splay, twitching, uncoordinated movement/ataxia, and convulsions.

• Page 4. A developmental neurotoxicity (DNT) study on bifenthrin with rats has been submitted. In this study, maternal and offspring toxicity was observed at the same dose levels. The maternal toxicity was primarily manifested as tremors, clonic convulsions, and increased grooming counts. The offspring toxicity was manifested as increased grooming counts. This study does not show any evidence of increased susceptibility of offspring following exposure to bifenthrin.

• Pages 13-14. The CPRC (1992) has characterized bifenthrin as Category C (possible human carcinogen) and recommended that for the purpose of risk characterization, the RfD approach should be used for quantification of human cancer risk. This decision was based in part on the statistically significant increased trend for hemangiopericytomas in the urinary bladders’ of Swiss Webster mice. The incidence of these lesions was double at the highest dose tested (HDT; 600 ppm) as compared to controls. The male mice also had significant dose-related trends with respect to hepatocellular carcinomas and combined hepatocellular adenomas and carcinomas, and increased incidences of bronchioalveolar adenomas and adenocarcinomas of the lung in females at 50, 200 and 600 ppm (but not 500 ppm) relative to their controls.

• Page 24. In a 2-generation study (MRID 00157225), liquified bifenthrin (88.35% ai) mixed with acetone was administered in the diet to TAC(SD)fBR rats (25/sex/dose) at dose levels of 0, 30, 60, or 100 ppm as FMC 54800 technical (approximately equivalent to 0, 1.5, 3.0 and 5.0 mg/kg/day)... In the high-dose P generation females, there was a statistically significant increase in absolute and relative brain weights... In the 100 ppm group F1b female progeny, absolute adrenal and heart weights were statistically elevated compared to control values. Significantly elevated absolute ovary and ovary/brain weights were also observed in these animals.

August 1, 2007 EPA-HQ-OPP-2007-0471

IR-4. Pesticide Petitions PPs 6E7125, 6E7126, 6E7127 and 6E7128. Proposal to establish a
tolerance for residues of the insecticide bifenthrin in or on food commodities

Commodity
PPM
pistachio
0.05
mayhaw
1.4

vegetables, fruiting, group 8

This group includes 17 commodities.
chili, postharvest • eggplant • groundcherry • pepino • pepper • pepper, bell • pepper, nonbell • pepper, nonbell, sweet • tomatillo • tomato • tomato, concentrated products • tomato, dried pomace • tomato, paste • tomato, puree • tomato, wet pomace • vegetable, fruiting • vegetable, fruiting, group

0.5
peanut
0.05
soybean
0.2

vegetable, root, except sugar beet and garden beet, subgroup 1B

This subgroup includes 19 commodities.
beet, garden • burdock, edible • carrot • carrot culls • celeriac • chervil, turnip rooted • chicory root • ginseng • horseradish • parsley, turnip rooted • parsnip • radish • radish, oriental • rutabaga • salsify • salsify, black • salsify, spanish • skirret • turnip

0.07
beet, garden, roots
0.45
beet, garden, tops
15

There is a practical analytical method for detecting and measuring levels of bifenthrin in or on food with a limit of detection that allows monitoring of food with residues at or above the levels set in these tolerances gas chromatography with electron capture detection (GC/ECD).

August 1, 2007 EPA-HQ-OPP-2007-0535

R-4. Pesticide Petition PP 7E7227. Proposal to establish a tolerance for residues of the insecticide bifenthrin in or on food commodities:

Commodity
PPM

bushberry subgroup 13-B

This subgroup includes 5 commodities.
blueberry • currant • elderberry • gooseberry • huckleberry

2.0
juneberry
2.0
lingonberry
2.0
salal
2.0
aronia berry
2.0
blueberry, lowbush
2.0
buffalo currant
2.0
chilean guava
2.0
European barberry
2.0
highbush cranberry
2.0
honeysuckle
2.0
jostaberry
2.0
native currant
2.0
sea buckthorn
2.0

leafy petioles subgroup 4-B

This subgroup includes 8 commodities.
amaranth, leafy • cardoon • celery • celery, chinese • celtuce • fennel, florence • rhubarb • swiss chard

3.0

There is a practical analytical method for detecting and measuring levels of bifenthrin in or on food with a limit of detection that allows monitoring of food with residues at or above the levels set in these tolerances GC/ECD.

February 28, 2007 EPA-HQ-OPP-2007-0005 Notice of Receipt of Request to Voluntarily Cancel Certain Pesticide Registrations.
Registration No. Product Name Registrant
000279-03135 Bistar T&O EC Insecticide FMC Corp. Agricultural Products Group
1735 Market St,
Philadelphia, PA 19103
December 20, 2006 EPA-HQ-OPP-2006-0942 Extension of Tolerances for Emergency Exemptions
This regulation extends time-limited tolerances on orchardgrass for control of the orchardgrass billbug in Oregon. This regulation extends time-limited tolerances for residues of the insecticide bifenthrin in or on
-- orchardgrass, forage and orchardgrass, hay at 0.05 ppm
for an additional 2-year period. These tolerances will expire and are revoked on December 31, 2009.
August 25, 2006 EPA-HQ-OPP-2006-0659 Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations
• Oregon: EPA authorized the use of bifenthrin on orchardgrass grown for seed to control the orchardgrass billbug; April 21, 2006 to November 15, 2006.
• Louisiana: EPA authorized the use of bifenthrin on sweet potato to control soil beetles and the sweet potato weevil; May 15, 2006 to November 30, 2006.
August 11, 2006 EPA-HQ-OPP-2006-0366

IR-4. Pesticide tolerance. FINAL RULE.
-- Coriander, dried leaves at 25 ppm
-- Coriander, leaves at.6.0 ppm
-- Coriander, seed at 5.0 ppm
-- Okra at 0.50 ppm
-- Turnip, greens at 3.5 ppm

-- Pea and bean, dried shelled, expect soybean, subgroup 6C at 0.15 ppm

This subgroup includes 27 commodities. bean, adzuki • bean, broad dry • bean, dry • bean, kidney • bean, lablab • bean, lima dry • bean, moth • bean, mung • bean, navy • bean, pink • bean, pinto • bean, rice • bean, tepary • bean, urd • catjang • chickpea • cowpea • guar • lentil • lupin, grain • lupin, sweet • pea, blackeyed • pea, crowder • pea, field • pea, field seed • pea, pigeon • pea, southern

-- Brassica, leafy greens, subgroup 5B ...... 3.5 ppm

This subgroup includes 8 commodities: broccoli raab • cabbage, chinese bok choy • collards • kale • mizuna • mustard greens • mustard spinach • rape greens

-- Vegetable, tuberous and corm, subgroup 1C ...... 0.05 ppm

This subgroup includes 22 commodities: arracacha • arrowroot • artichoke, chinese • artichoke, jerusalem • canna, edible • cassava • chayote root • chufa • dasheen • ginger • leren • potato • potato culls • potato granules flakes • potato peel, wet • potato processed potato waste • potato, specialty • sweet potato • tanier • turmeric • yam bean • yam, true

June 28, 2006 EPA-HQ-OPP-2006-0084

Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide Registrations.

Registration No. Product Name Registrant
001381-00193 Tundra EC Agriliance, LLC,
PO Box 64089,
St. Paul, MN 551640089
June 7, 2006 EPA-HQ-OPP- 2006-0387

Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations.
-- Mississippi: EPA authorized the use of bifenthrin on sweet potatoes to control beetle complex; March 27, 2006 to September 30, 2006.
-- North Carolina: EPA authorized the use of bifenthrin on sweet potatoes to control beetle complex; March 27, 2006 to October 31, 2006.

May 10, 2006 EPA-HQ-OPP-
2006-0366

IR-4. Pesticide petitions: PP 2E6451, 3E6882, 2E6492, 2E6423, and 4E6843.
in and/or on:
-- cilantro at 5.0 ppm (4E6843).
-- turnip greens at 3.0 ppm (2E6451)
-- okra at 0.5 ppm (2E2649)

-- leafy brassica greens, subgroup 5B at 3.0 ppm (2E6451)

This subgroup includes 8 commodities.
broccoli raab • cabbage, chinese bok choy • collards • kale • mizuna • mustard greens • mustard spinach • rape greens

-- tuberous and corm vegetables, subgroup 1C at 0.1 ppm (3E2688)

This subgroup includes 22 commodities.
arracacha • arrowroot • artichoke, chinese • artichoke, jerusalem • canna, edible • cassava • chayote root • chufa • dasheen • ginger • leren • potato • potato culls • potato granules flakes • potato peel, wet • potato processed potato waste • potato, specialty • sweet potato • tanier • turmeric • yam bean • yam, true

-- dried shelled pea and bean (except soybean), subgroup 6C at 0.1 ppm (2E6423)

This subgroup includes 27 commodities.
bean, adzuki • bean, broad dry • bean, dry • bean, kidney • bean, lablab • bean, lima dry • bean, moth • bean, mung • bean, navy • bean, pink • bean, pinto • bean, rice • bean, tepary • bean, urd • catjang • chickpea • cowpea • guar • lentil • lupin, grain • lupin, sweet • pea, blackeyed • pea, crowder • pea, field • pea, field seed • pea, pigeon • pea, southern

Nov 16, 2005 OPP-2005-0277 Pesticide Emergency Exemptions.
• Oregon. EPA authorized the use of bifenthrin on orchardgrass to control the orchardgrass billbug; July 8, 2005 to November 15, 2005.
August 31, 2005 OPP-2005-0223

Pesticide Emergency Exemptions:

• Louisiana. Specific: EPA authorized the use of bifenthrin on sweet potato to control soil beetle complex; April 29, 2005 to November 30, 2005. Contact: (Andrea Conrath).
• Mississipi. EPA authorized the use of bifenthrin on sweet potato to control soil beetle complex; April 29, 2005 to September 30, 2005. Contact: (Andrea Conrath).
• North Carolina. Specific: EPA authorized the use of bifenthrin on sweet potato to control beetle complex; April 1, 2005 to September 30, 2005. Contact: (Libby Pemberton).

August 3, 2005 OPP-2005-0201

Cancellation of Pesticides for Non-payment of Year 2005 Registration Maintenance Fees.

Section 24(c) Registrations canceled for non-payment of the 2005
maintenance fee are shown in the following Table 1:

Table 1.--Section 24(c) Registrations Canceled for Non-Payment of Maintenance Fee

SLN no. Product Name
000279 WY-97-0004 Capture 2 EC Insecticide/miticide

Section 3 registrations canceled for non-payment of the 2005
maintenance fee are shown in the following table 2:

Table 2.--Section 3 Registrations Canceled for Non-Payment of
Maintenance Fee

Registration no. Product Name
074627-00003 Nab 2.4 ME Insecticide
Feb 10, 2005 OPP-2005-0025 Removal of Expired Time-limited Tolerances for Emergency Exemptions. FINAL RULE.
• 3. Bifenthrin. Time-limited tolerances for peanut and potato are being removed from Sec. 180.442 because they expired on or before December 31, 2003.
Dec 22, 2004 OPP-2004-0350 Pesticide Emergency Exemptions.
North Carolina - EPA authorized the use of bifenthrin on sweet potatoes to control beetle complex; August 12, 2004 to September 30, 2004. Contact: (Libby Pemberton)
Nov 10, 2004 OPP-2004-0232

Four Pesticide Emergency Exemptions.
Arkansas - EPA authorized the use of bifenthrin on sweet potatoes to control beetle complex; April 29, 2004 to November 30, 2004. Contact: (Stacey Groce)
Louisiana - EPA authorized the use of bifenthrin on sweet potatoes to control beetle complex; May 20, 2004 to November 30, 2004. Contact: (Stacey Groce).
Mississippi - EPA authorized the use of bifenthrin on sweet potatoes to control beetle complex; April 29, 2004 to September 30, 2004. Contact: (Stacey Groce).
North Carolina - On June 2, 2004, for the use of bifenthrin on sweet potatoes to control wireworm. This program is expected to end on September 30, 2004. Contact: (Libby Pemberton).

Oct 27, 2004 OPP-2004-0338 Cancellation of Pesticides for Non-payment of Year 2004 Registration Maintenance Fees.
Table 1.--Section 24(c) Registrations Canceled for Non-Payment of Maintenance Fee
Name of Pesticide Product Name Registrant SLN No.
Bifenthrin Biflex TC Termiticide FMC Corp Agricultural Products Group 000279 LA-96-0013
Bifenthrin Biflex TC Termiticide FMC Corp Agricultural Products Group 000279 MS-97-0002
May 24, 2004 OPP-2004-0136 Extension of Tolerances for Emergency Exemptions. FINAL RULE. EPA has authorized under FIFRA section 18 the use of bifenthrin on orchardgrass, forage and orchardgrass, hay for control of orchardgrass billbug in Oregon. This regulation extends time-limited tolerances for residues of the insecticide bifenthrin in or on orchardgrass, forage and orchardgrass, hay at 0.05 ppm for an additional 3-year period. These tolerances will expire and are revoked on June 30, 2007. Time-limited tolerances were originally published in the Federal Register of July 26, 2002.
May 5, 2004 OPP-2004-0116

Pesticide Emergency Exemptions.
Oregon - EPA authorized the use of bifenthrin on orchardgrass grown for seed to control the orchardgrass billbug; March 30, 2004 to November 15, 2004.

March 4, 2004 ORD-2003-
0011

Announcement: Longitudinal Study of Young Children's Exposures in their Homes to Selected Pesticides, Phthalates, Brominated Flame Retardants, and Perfluorinated Chemicals (A Children's Environmental Exposure Research Study--CHEERS).

Abstract: The U.S. EPA's Office of Research and Development's National Exposure Research Laboratory proposes to conduct a two-year longitudinal field measurement study of young children's (aged 0 to 3 years) potential exposures to current-use pesticides and selected phthalates, polybrominated diphenyl ethers, and perfluorinated compounds that may be found in residential environments. The study will be conducted in Duval County, Jacksonville, Florida over a two-year period from 2004 to 2006. Sixty young children will be recruited into this study in two cohorts: (1) infants recruited into the study soon after birth, and, (2) children recruited into the study at approximately 12 months of age. ...

Part A: Supporting Statement - EPA ICR Number: 2126.01 - 61 pages
From Table 2:
• Of 16 pesticides included in this study, 4 are fluorinated:
Bifenthrin, Fipronil, lamda-Cyhalothrin, and Cyfluthrin I, II, III, IV, total
• Perfluorinated chemicals:
Perfluorooctanoic acid (PFOA) and Perfluorooctane sulfonate (PFOS)

From Table 3: List of chemicals to be analyzed in biological media:
• one is fluorinated: 4-fluoro-3-phenoxybenzoic acid
• Perfluorooctanoic acid/Perfluorooctane sulfonate

Jan 14, 2004 OPP-2003-0402 Extension of Tolerances for Emergency Exemptions. FINAL RULE. EPA has authorized under FIFRA section 18 the use of bifenthrin on sweet potatoes for control of soil beetles and weevils in Louisiana and Mississippi. This regulation extends a time-limited tolerance for residues of the insecticide bifenthrin in or on
sweet potato, roots at 0.05 ppm for an additional 2-year period. This tolerance will expire and is revoked on December 31, 2005.
A time-limited tolerance was originally published in the Federal Register of September 27, 2001, subsequently corrected by a technical amendment published in the Federal Register of September 3, 2003.
Nov 26, 2003 OPP-2003-0358 3 Approved Requests for Pesticide Emergency Exemptions.
-- Louisiana Department of Agriculture and Forestry. EPA authorized the use of bifenthrin on sweet potatoes to control soil beetles, and sweet potato weevil; May 19, 2003 to November 30, 2003.
-- Mississippi Department of Agriculture and Commerce. EPA authorized the use of bifenthrin on sweet potatoes to control soil beetles; May 19, 2003 to September 30, 2003.
-- Oregon Department of Agriculture. EPA authorized the use of bifenthrin on orchardgrass grown for seed to control the orchardgrass billbug; April 4, 2003 to November 15, 2003.
Sept 3, 2003 OPP-2003-0288 Pesticide Tolerance for Emergency Exemption; Technical Amendment. Final Rule. EPA issued a final rule in the Federal Register of September 27, 2001 to establish a time-limited tolerance for residues of bifenthrin in or on sweet potato at 0.05 ppm. This action was in response to EPA's granting of an emergency exemption under section 18 of the Federal Insecticide, Fungicide, and Rodenticide Act authorizing use of the pesticide on sweet potato. The amendment to establish the tolerance for bifenthrin inadvertently added the tolerance for ``sweet potato'' to 40 CFR 180.442(a). However, 40 CFR 180.442(a) is not designated for section 18 emergency exemptions; consequently, the entry for sweet potato could not be added to Sec. 180.442(a) by the Office of the Federal Register. This technical amendment is being issued to correctly add the tolerance for sweet potato to the table in Sec. 180.442(b), which is designated for time-limited tolerances associated with section 18 emergency exemptions.
-- EPA is also changing the commodity term ``sweet potato'' to read ``sweet potato, roots.''
April 30, 2003 OPP-2002-0358

FMC; IR-4. New Pesticide Tolerances. FINAL RULE. This regulation establishes tolerances for residues of bifenthrin in or on

Commodity Final Rule
Parts per million
Proposed Tolerances Pesticide Petition

 

Date Petition published in FR

Note from FAN - Original Petitioner
Food products in food handling establishments 0.05 0.01 PP 2F6390 Feb 15, 2002 FMC - Feb 15, 2002
Almond, hulls 2.0 2 PP 6F3454 Feb 15, 2002 FMC - Feb 15, 2002
Banana - Imported 0.1 0.1 PP 0E6216 Feb 14, 2001 FMC - Feb 14, 2001
Carambola (starfruit) - imported Determined by EPA to be insufficient to support the proposed tolerances; subsequently withdrawn by the Taipei Economic and Cultural Representative Office. 1.0 PP 1E6234 Feb 15, 2002 The Taipei Economic and Cultural Representative Office in the United States - Feb 15, 2002
Fruit, citrus, group 10 0.05 0.05 PP 1F6266 Feb 14, 2001 FMC - Feb 14, 2001
EPA is deleting time-limited tolerances established for residues of bifenthrin in or on citrus, dried pulp, at 0.3 ppm, citrus oil at 0.3 ppm and citrus, whole fruit, at 0.05 ppm in connection with section 18 emergency exemptions granted by EPA. With the establishment of the citrus fruit group tolerance (PP 1F6266), these tolerances are no longer needed.
Herb subgroup 19A 0.05 0.05 PP 0E6157 Feb 15, 2002 IR-4 - Feb 15, 2002
Herb subgroup 19A includes:
(allspice; angelica; anise hyssop, leaves; anise, seed; anise, star; annatto, seed; basil, dried leaves; basil, fresh leaves; borage, dried leaves; borage, fresh leaves ;burnet, leaves; camomile; caper, buds; caraway, black, seed caraway, seed; cardamom, seed; cardamon amomum, seed; cassia; catnip; celery, seed; chervil, dried leaves; chive, chinese; chive, leaves; cinnamon; clary, dried leaves; clary, fresh leaves; clove; coriander, leaves; coriander, seed; costmary, dried leaves; costmary, fresh leaves; culantro, leaves; culantro, seed; cumin; curry, dried leaves; curry, fresh leaves; dill, seed; dillweed, dried leaves; dillweed, fresh leaves; fennel, florence, seed; fennel, seed; fenugreek, seed; grains of paradise, seed; horehound, leaves; hyssop, tops; juniper berry; lavender; lemongrass, leaves; lovage, leaves; lovage, seed; mace; marjoram, tops; mustard, seed; nasturtium, leaves; nutmeg; parsley, dried leave;s pennyroyal, leaves; pepper, black pepper;, white poppy, seed; rosemary, dried leaves; rosemary, fresh leaves; rue, dried leaves; rue, fresh leaves; saffron, stigma; sage, dried leaves; sage, fresh leaves; savory, summer, dried leaves; savory, summer, fresh leaves; savory, winter, dried leaves; savory, winter, fresh leaves; sweet bay, dried leaves; tansy, dried leaves tansy, fresh leaves; tarragon, dried leaves; tarragon, fresh leaves; thyme, dried leaves; thyme, fresh leaves; vanilla; wintergreen, dried leaves; wintergreen, fresh leaves; woodruff, dried leaves; woodruff, fresh leaves; wormwood, dried leaves; wormwood, fresh leaves)
Leaf petioles subgroup (4B) (includes cardoon, celery, Chinese celery, celtuce, Florence fennel, rhubarb, Swiss chard)
Determined by EPA to be insufficient to support the proposed tolerances; cannot be established until adequate residue chemistry data are submitted and reviewed. 2.0 PP 6E4630 Feb 15, 2002 IR-4 - Feb 15, 2002
Nut, tree, group 14
(almond; almond, hulls; beechnut; butternut; cashew; chestnut; chinquapin; filbert; nut brazil; nut, hickory; nut, macadamia; pecan; pistachio; walnut)
0.05 0.05 PP 6F3454 Feb 15, 2002 FMC - Feb 15, 2002
Pear 0.5 1.0 PP 6F3454 Feb 15, 2002 FMC - Feb 15, 2002
Spinach 0.2 0.2 PP 2E6402 Feb 15, 2002 IR-4 - Feb 15, 2002
Tomato 0.15 0.15 PP 1E6330 Feb 15, 2002 IR-4 - Feb 15, 2002

-- Category C (possible human) carcinogen, primarily on the basis of the mouse carcinogenicity study in which the high-dose males (81.3 mg/kg/day) showed a highly significant increased incidence of urinary bladder tumors. Other findings in the mouse study included a dose-related trend of increased combined incidences of adenoma and adenocarcinoma of the liver (males only), and increased incidences of bronchioalveolar adenomas and adenocarcinomas of the lung in females at some, but not all, doses relative to their controls.
-- Acute Neurotoxicity Study in Rats. LOAEL = 70.3 mg/kg/day. based on observations of mortality (females only), clinical and functional operational battery (FOB) findings and differences in motor activity.
-- 1-Year Oral Study in Dogs. LOAEL = 2.7 mg/kg/day based on observations of increased incidence of tremors in both sexes.
-- 90-Day Oral Study in Dogs. LOAEL = 4.42 mg ai/kg/ day based on observations of increased incidence of tremors in both sexes.
-- 21-Day Dermal Study in Rats. LOAEL = 93 mg/kg/day based on observations of clinical signs (staggered gait and exaggerated hindlimb flexion).

April 16, 2003 OPP-2003-0116 

Requests to voluntarily cancel certain pesticide registrations. EPA is issuing a notice of receipt of request by registrants to voluntarily cancel certain pesticide registrations. Unless a request is withdrawn by October 13, 2003, or May 16, 2003 for EPA Registration Numbers: 003008-00021, 075341-00001, and 075341-00007, orders will be issued canceling these registrations.

Product Registration Number Company Name and Address
Biflex TC Termiticide 000279 AZ-95-0004 FMC Corp.Agricultural Products Group,
1735 Market St, Philadelphia, PA 19103.
Feb 24, 2003 OPP-2003-0033

Pesticide Emergency Exemption.

Texas. Specific: EPA authorized the use of bifenthrin on citrus to control weevils; November 22, 2002 to November 22, 2003.

Jan 16, 2003 OPP-2002-0336  

Extension of Tolerances for Emergency Exemptions. EPA has authorized under FIFRA section 18 the use of bifenthrin on citrus for control of weevils in Texas and Florida. This regulation extends time-limited tolerances for residues of the insecticide bifenthrin in or on citrus, dried pulp and citrus, oil at 0.3 ppm for an additional 2-year period. This tolerance will expire and is revoked on December 31, 2004. A time- limited tolerance was originally published in the Federal Register of December 16, 1998 (63 FR 69200) (FRL-6048-1).

Nov 27, 2002 OPP-2002-0313 

EPA approved the use of Bifenthrin for 5 Emergency Exemptions.

-- Kansas: EPA authorized the use of bifenthrin on sorghum grown for seed to control banks grass mite; August 16, 2002 to September 30, 2002.
-- Louisiana: Crisis: On May 3, 2002, for the use of bifenthrin on sweet potatoes to control soil beetles and sweet potato weevils. This program is expected to end on November 30, 2002.
-- Louisiana: EPA authorized the use of bifenthrin on sweet potatoes to control soil beetles and sweet potato weevils; July 19, 2002 to November 30, 2002.
-- Mississippi: EPA authorized the use of bifenthrin on sweet potatoes to control soil beetles; July 19, 2002 to September 30, 2002.
-- Texas: EPA authorized the use of bifenthrin on sorghum grown for seed to control banks grass mite; August 16, 2002 to August 16, 2003.

July 26, 2002 OPP-2002-0145 

Pesticide Tolerances for Emergency Exemptions for time-limited tolerances for residues of bifenthrin in or on orchardgrass hay and forage at 0.05 ppm. Final Rule. The tolerance will expire and is revoked on June 30, 2004.

Oregon produces nearly all of the nation's orchardgrass seed, which is primarily used as a high protein pasture grass. No orchardgrass residue data were submitted for this request. The proposed use rate of bifenthrin for orchardgrass is approximately the same as that registered for use on alfalfa grown for seed. Therefore, the data from alfalfa was translated to orchardgrass for this section 18 use. The established tolerances for meat and milk commodities are adequate to cover any residues which may result from this section 18 use... EPA concluded that exposure to bifenthrin from food will utilize 60% of the acute population adjusted dose (aPAD) for the U.S. population, 40% for females 13 years and older, 75% for all infants 1 year old, and 99.7% of the aPAD for children 1 to 6 years old. In addition, despite the potential for acute dietary exposure to bifenthrin in drinking water, after calculating drinking water levels of concern (DWLOCs) and comparing them to conservative model estimated environmental concentrations (EECs) of bifenthrin in surface and ground water, EPA does not expect the aggregate exposure to exceed 100% of the aPAD...

Bifenthrin has been classified as a Group C chemical (possible human carcinogen) based upon urinary bladder tumors in mice.

Conditions. One application may be made. A maximum of 0.10 pound of active ingredient may be applied per acre using ground equipment. Bifenthrin is not to be applied within 30 days of grazing, feeding, or harvesting (cutting) forage or hay.

May 17, 2002 OPP-2002-0037 Revocation of Expired Time Limited Tolerances. Final Rule. Time-limited tolerances for broccoli; cabbage; canola seed; cauliflower; grapes; raspberries; and cucurbit vegetables are being removed from 40 CFR 180.442 because they expired on or before December 31, 2001.
Feb 15, 2002 PF-1069
  • Seven Pesticide Petitions to establish new tolerances:
  • FMC: PP 2F6390 proposes a tolerance in or on food products in food handling establishments at 0.01 ppm.
  • FMC: PP 6F3454 proposes a tolerance in or on the raw agricultural commodity pears at 1.0 ppm, in or on almond hulls at 2 ppm and in or on the tree nuts crop group at 0.05 ppm.
  • IR-4: PP 6E4630 proposes a tolerance for the leaf petioles subgroup (4B) (includes cardoon, celery, Chinese celery, celtuce, Florence fennel, rhubarb, Swiss chard) at 2.0 ppm.
  • IR-4: PP 0E6157 proposes a tolerance for the herb subgroup (19A) at 0.05 ppm.
  • IR-4: PP 1E6330 proposes a tolerance for tomato at 0.15 ppm.
  • IR-4: PP 2E6402 proposes a tolerance for spinach at 0.2 ppm.
  • Taipei Economic and Cultural Representative Office in the U.S.: 1E6234 request to establish an import tolerance for residues of bifenthrin in or on carambola (starfruit) at 1.0 ppm. Docket control number PF-1069
Feb 13, 2002 OPP-181085
  • Emergency Exemptions:
  • Texas: Crisis: On March 21, 2001, for the use of bifenthrin on citrus to control weevils. This program is expected to end on November 14, 2002.
  • Texas: Specific: EPA authorized the use of bifenthrin on citrus to control weevils; November 14, 2001 to November 14, 2002.
Dec 14, 2001 OPP-301194 Extension of time-limited tolerance for residues - FINAL RULE: in or on peanuts, nutmeats at 0.05 ppm for an additional 2-year period. This tolerance will expire on December 31, 2003. Objections and requests for hearings, identified by docket control number OPP-301194, must be received by EPA on or before January 14, 2002.
Nov 14, 2001 OPP-181082
  • 3 Pesticide Emergency Exemptions: EPA authorized use in:
  • Florida: on citrus to control diaprepes root weevil; March 2, 2001 to March 2, 2002.
  • Oklahoma: on peanuts to control spider mites; July 15, 2001 to October 30, 2001.
  • Texas: on sorghum grown for seed to control Banks grass mite; August 1, 2001 to August 1, 2002.
Oct 3, 2001 na
  • Public Report on Minor Use Pesticides; Notice of Availability.
  • "Minor uses of pesticides are those for which the total U.S.acreage for a particular crop is less than 300,000 acres or those for which the use does not provide sufficient economic incentive to support its registration." - see Report cited in the Federal Register which includes the following fluorinated pesticides:
  • Bifenthrin Insecticide (Trade names Capture, Brigade, Talstar, Biflex)
  • Diflubenzuron Insect Growth Regulator Insecticide (Trade name Dimilin)
  • Fludioxonil Fungicide (Trade names Maxim, Medallion)
Sept 27, 2001 OPP-301169
Feb 14, 2001 PF-998

FMC - Pesticide Tolerance Petition for residues in or on bananas at 0.1 ppm.

Dec 20, 2000 OPP-181078 Pesticide Emergency Exemptions for use on citrus in FL, on seed sorghum in KS and TX, on peanuts in OK., potatoes and raspberries in OR and WA
Sept 27, 2000 OPP-301047 Pesticide Time-Limited Tolerances for Emergency Exemptions for potato at 0.05 ppm. - FINAL RULE.
Dec 22, 1999 PF-903
June 30, 1999 OPP-300888 Pesticide Tolerances for various AG commodities (including, in or on Cabbage at 4 ppm)- FINAL RULE.
May 26, 1999 na

FMC - Request to Voluntarily Cancel the product: Talstar 10WP Insecticide/miticide.

May 19, 1999 PF-873
  • IR-4 * - Filing of Seven Pesticide Petitions for tolerances of residues in or on the raw agricultural commodities.
  • PP 6E4629 proposes the establishment of a tolerance for artichoke at 1 ppm.
  • PP 6E4760 proposes the establishment of a tolerance for crop group 9 cucurbit vegetables at 0.4 ppm.
  • PP 8E4993 proposes the establishment of a tolerance for crop subgroup 6B edible-podded legume vegetables at 0.2 ppm.
  • PP 8E5009 proposes the establishment of a tolerance for eggplant at 0.05 ppm.
  • PP 9E5084 proposes the establishment of a tolerance for rapeseed including, canola and crambe seed, at 0.05 ppm.
  • PP 9E5069 proposes the establishment of a tolerance for crop subgroup 5A Head and Stem Brassica, excluding cabbage, at 0.6 ppm and cabbage at 4.0 ppm.
  • PP 9E5064 proposes the establishment of a tolerance for crop subgroup 6B, succulent shelled peas and beans at 0.5 ppm.
May 19, 1999 PF-873

FMC - Pesticide Tolerance Petition for residues in or on the raw agricultural commodity sweet corn at 0.05 ppm; and proposal to amend the existing tolerance for corn forage from 2.0 to 3.0 ppm.

April 28, 1999 OPP-300852 Extension of Tolerance for Emergency Exemptions for residues of the insecticide and its metabolites in or on cucurbits at 1 ppm for an additional 18 month period. - FINAL RULE. This tolerance will expire and is revoked on October 31, 2000.
March 24, 1999 na Request to voluntarily cancel 2 pesticide registrations: Talstar Granular, EPA Reg. No. 000279 AZ-93-0017; and Talstar 10WP Insecticide/miticide, EPA Reg. No. 000279 AZ-93-0018.
March 10, 1999 OPP-181067 Application for Emergency Exemption. EPA has received a specific exemption request from the Washington Department of Agriculture to use the pesticide bifenthrin (CAS 8657-04-3 cis and 83322-02-5 trans), formulated as Brigade WSB, to treat up to 8,500 acres of raspberries to control weevils. This is the seventh year this use has been requested, and it has been allowed under section 18 for the past 6 years. Since this request proposes a use which has been requested or granted in any 3 previous years, and a complete application for registration and petition for tolerance has not yet been submitted to the Agency, EPA is soliciting public comment before making the decision whether or not to grant the exemption.
Dec 16, 1998 OPP-300762 Pesticide Tolerances for Emergency Exemptions for residues of in or on CITRUS: whole fruit at 0.05 ppm; oil and dried pulp at 0.3 ppm. - FINAL RULE. These tolerances will expire and are revoked on December 31, 2000.
Oct 7, 1998 PF-831

FMC - Pesticide Tolerance Petition for residues in or on the raw agricultural commodity corn, grain (sweet) at 0.05 ppm and corn, forage at 3.0 ppm.

July 10, 1998 OPP-300677 Pesticide Tolerances for Emergency Exemptions. - FINAL RULE. This regulation establishes a time-limited tolerance for residues of bifenthrin in or on raspberries at 3 ppm.
April 1, 1998 OPP-300630 Extension of Tolerance for Emergency Exemptions for residues of the insecticide and its metabolites in or on cucurbits at 1.0 ppm for an additional one-year period.- FINAL RULE. This tolerance will expire and are revoked on April 30, 1999.
March 25, 1998 OPP-181057 Application for Emergency Exemption. EPA has received a specific exemption request from the Washington Department of Agriculture to use the pesticide bifenthrin (CAS 8657-04-3 cis and 83322-02-5 trans), formulated as Brigade WSB, to treat up to 9,500 acres of raspberries to control weevils. This is the sixth year this use has been requested, and it has been allowed under section 18 for the past 5 years. If all 9,500 acres are treated at this maximum rate, this could potentially result in a total use of 1,900 lb. of active ingredient.
Feb 9, 1998 na Technical Amendments to Pesticide Tolerance; Correction of Effective Date Under Congressional Review Act (CRA). - FINAL RULE. On June 12, 1996 (61 FR 29676), the EPA published in the Federal Register a final rule establishing a tolerance for residues of the pesticide bifenthrin in or on the raw agricultural commodity strawberries, which established an effective date of June 12, 1996. This document corrects the effective date of the rule to February 9, 1998 to be consistent with sections 801 and 808 of the CRA.
Jan 14, 1998 OPP-300593 Pesticide Tolerances for Emergency Exemptions. - FINAL RULE. This regulation establishes a time-limited tolerance for residues of bifenthrin in or on cabbage at 2 ppm. The tolerance will expire and is revoked on December 31, 1998.
Jan 9, 1998 OPP-300600 Extension of Tolerance for Emergency Exemptions. - FINAL RULE. This rule extends a time-limited tolerance for residues of the insecticide bifenthrin in or on broccoli and cauliflower at 0.1 and 0.05 ppm, respectively, for an additional 1-year period, to January 31, 1999.
Nov 26, 1997 OPP-300579 Pesticide Tolerances for various AG commodities (including dried hops at 10 ppm; corn fooder at 5 ppm. FINAL RULE.
Oct 29, 1997 OPP-181049 Request for Emergency Exemption for Bifenthrin, formulated as Capture 2EC, to treat up to 22,000 acres of broccoli, cauliflower, cabbage, and rapini; and 40,000 acres of lettuce, to control silverleaf whitefly. Specific exemption request from the California Department of Pesticide Regulations
Oct 3, 1997 - Final na Cut Roses. Exception Decisions to Early Entry Prohibition, Worker Protection Standard; Technical Amendment. - FINAL RULE. See also Federal Register of Oct 30, 1996 below.
Oct 3, 1997 -Proposed OPP-250121 Pesticide Worker Protection Standard; Administrative Exception for Cut-Rose Hand Harvesting; Administrative Decision. Proposed Rule.
Sept 25, 1997 PF-767

FMC - Filing of Pesticide Petition to remove limitations on tolerances in or on cottonseed and grain corn at 0.5 ppm, dried hops at 10 ppm; and strawberries at 3.0 ppm.

Sept 5, 1997 OPP-300543 Pesticide Tolerances for Emergency Exemptions. - FINAL RULE. This regulation establishes a time-limited tolerance for residues of bifenthrin in or on canola seed at 0.5 ppm. The tolerance will expire and is revoked on September 30, 1998.
August 4, 1997 OPP-300523 Pesticides Subject to Tolerance Reassessment.
June 6, 1997 OPP-300495 Pesticide Tolerances for Emergency Exemptions. - FINAL RULE. This regulation establishes time-limited tolerances for residues of the pesticide bifenthrin in or on the raw agricultural commodity crop group, cucurbits: Broccoli at 0.1 ppm, Cauliflower at 0.05 ppm; and cucurbits (Crop Group 9 - cucumbers, melons, and squash) at 1 ppm; and in or on the raw agricultural commodity raspberries at 3 ppm in California, Arizona, and Texas; and use of bifenthrin on raspberries in Oregon and Washington. These tolerances will expire and are revoked on April 30, 1998 (cucurbits) and September 30, 1997 (raspberries).
March 5, 1997 OPP-181034 Application for Emergency Exemption. EPA has received a specific exemption request from the Washington Department of Agriculture (hereafter referred to as the ``Applicant'') to use the pesticide bifenthrin (CAS 82657-04-3 cis and 83322-02-5 trans), formulated as Brigade WSB, to treat up to 9,500 acres of raspberries to control weevils. This is the fifth year this use has been requested, and it has been allowed under section 18 for the past 4 years. Since this request proposes a use which has been requested or granted in any 3 previous years, and a complete application for registration and petition for tolerance has not yet been submitted to the Agency, EPA is soliciting public comment.
Feb 12, 1997 OPP-300452 Pesticide Tolerances for Emergency Exemptions. - FINAL RULE. This regulation establishes a time-limited tolerance for combined residues of the insecticide bifenthrin in or on the raw agricultural commodities broccoli at 0.1 ppm and cauliflower at 0.05 ppm. These tolerances will expire and be revoked automatically without further action by EPA on January 31, 1998.
Oct 30, 1996 na Emergency Exemption for use on canola in MT.
Oct 30, 1996 OPP-300164I Cut-Roses; Request for Exception to Worker Protection Standard's Prohibition of Early Entry into Pesticide-Treated Areas to Harvest Roses by Hand Cutting.
August 7, 1996 OPP-181021 Application for Emergency Exemption on 62,000 acres in California.
June 19, 1996 na Emergency Exemptions for use on canola in ID, OR, WA.
June 12, 1996 PP 5F4485/R2232 Pesticide Tolerance of 3.0 ppm in and on strawberries. - FINAL RULE.
April 24, 1996 na Emergency Exemptions for use in California and Texas.
March 6, 1996 OPP-180993 Request for Emergency Exemptions for use on 141,000 acres in AZ and CA.
Feb 7, 1996 OPP-180987 Request for Emergency Exemption for use on 62,000 acres in California.
Dec 13, 1995 na Pesticide Emergency Exemptions for use in AZ, ND, TX, VA.
Sept 20, 1995 na Emergency Exemptions for use on canola in ID, OR, WA.
August 30, 1995 OPP-180979 Application for Emergency Exemption for use on sweetpotato in Arizona.
July 26, 1995 na Emergency Exemptions for use on strawberries in OR and WA, and raspberries in OR.
July 19, 1995 na Emergency Exemption for use on raspberries in WA.
June 15, 1995 PF-626; FRL 4955-4

FMC - Pesticide Tolerance Petition of 3.0 ppm for strawberries and various other AG commodities.

April 26, 1995 na Emergency Exemptions for use on cucurbits in California and Texas.
Jan 12, 1995 na Request for Emergency Exemptions for use on 200,000 acres of cucurbits and 36,000 acres of sweetpotato.
Dec 28, 1994 na Emergency Pesticide Use Exemptions for use in AZ, CA, TX.
Jan 12, 1994 OPPTS-400082 EPA's proposal to add 41 fluorine and organofluorine chemicals to the Toxics Release Inventory (TRI). See excerpt in box above. Also available at http://www.epa.gov/tri/frnotices/59fr1788.htm
* Interregional Project Number 4 (IR-4) Rutgers University, New Brunswick, NJ, 08903-0231
 
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