Flupropadine
CAS No. 81613-59-4
 
 

Activity: Rodenticide (unclassified)

CAS Name: 1-[3-[3,5-bis(trifluoromethyl)phenyl]-2-propynyl]-4-(1,1-dimethylethyl)piperidine

Structure:

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No 
Other Information
Molecular Formula: C20H23 F6 N 
Manufacturers: Aventis 
Other Names: M&B 36892 

Health Effects:

As of Nov 2002: no data available

Environmental Effects

As of Nov 2002: no data available

Note: the only information we could find on this rodenticide are the following 2 abstracts (as of Nov 23, 2002):

http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4067302&dopt=Abstract

J Hyg (Lond) 1985 Oct;95(2):513-8

Pen and field trials of flupropadine against the house mouse (Mus musculus L.).

Rowe FP, Bradfield A, Swinney T.

Laboratory and field trials were conducted to determine the efficacy of the candidate rodenticide flupropadine against the house mouse (Mus musculus L.). In laboratory feeding tests, family groups of wild mice maintained in pens and conditioned to feeding on plain foods were offered flupropadine at either 0.10%, 0.15%, 0.18% or 0.20% in pinhead oatmeal bait. Overall mortalities in replicated 21-day treatments were 66/71 (93.0%), 71/79 (89.9%), 72/76 (94.7%) and 69/75 (92.0%) respectively. In 17 field trials carried out against mice infesting farm buildings, flupropadine was used at 0.10%, 0.15% and 0.18% in oatmeal bait. Mean treatment success, estimated from live-capture and mortality data, was 88.6%, 96.2% and 96.6% respectively. Flupropadine was found to be as near effective against mice as calciferol/warfarin and the second-generation anticoagulant rodenticides difenacoum, bromadiolone and brodifacoum. In further comparison with the anticoagulants, treatment with flupropadine bait achieved markedly quicker control.


http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3840823&dopt=Abstract

J Hyg (Lond) 1985 Oct;95(2):505-12

Field trials of a new sub-acute rodenticide flupropadine, against wild Norway rats (Rattus norvegicus).

Buckle AP.

Fifteen experimental treatments with rodenticidal baits containing 0.1, 0.15 or 0.2% flupropadine were conducted on farmsteads against Rattus norvegicus infestations. Eight treatments were completely successful and the others gave kills ranging from 36 to 72% in 28 days. Treatments with 0.1 and 0.15% flupropadine were less successful against large infestations than against small ones. Flupropadine was most successful at 0.2% but still gave incomplete kills on farms where abundant alternative food was available. The compound was more effective than acute poisons in achieving complete control of Norway rat infestations, but was less reliable in doing so than anticoagulants. On the other hand, many flupropadine treatments gave quicker control and used smaller quantities of bait than anticoagulant treatments.

 
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