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Activity: Insecticide,
Termiticide (Benzoylurea)
Structure:
Adverse
Effects:
Blood
Eye
Kidney
Liver
Environmental
Hexaflumuron
is a termiticide first registered in the US in 1994.
Hexaflumuron
is the first active ingredient registered with the US EPA
as a reduced-risk persticide. A reduced risk pesticide is
one that EPA believes poses less risk to human health and
the environment than existing alternatives.
Ref: Technical Fact Sheet
for Hexaflumuron. National Pesticide Telecommunications
Network.
http://ace.orst.edu/info/npic/factsheets/hextech.pdf
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Blood
(click
on for all fluorinated pesticides)
Abstract: A toxicological
evaluation of a new insecticide Sonet was realized. It was established
that by its toxicity Sonet belongs to hazardous substances of
class III. The main manifestations of its toxic effect on the
body warm-blooded animals is its influence on the erythropoiesis
and functional
state of the liver.
Ref: Sviatnyi IM et al. (1992). [A hygienic
evaluation of the insecticide Sonet and the characteristics of
the mechanism of its toxic action in an experiment] [Article in
Russian]. Lik Sprava. Jan;(1):84-7.
http://www.fluorideaction.org/pesticides/hexaflumuron.abstracts.htm
Definition:
Erythropoiesis is the process of red blood
cell production (which occurs in red bone marrow).
Eye
(click
on for all fluorinated pesticides)
Recruit (hexaflumuron)
Health Effects: eye irritant, liver
and kidney damage
Ref: Physical Properties And Health Effects
of Pesticides Used On National Park Service Collections. Conserve
O Gram. U.S. National Park Service. September 2001. Number
2/17.
http://www.fluoridealert.org/pesticides/Natl.Park.Serv.Pesticides01.pdf
Kidney
(click
on for all fluorinated pesticides)
Recruit (hexaflumuron)
Health Effects: eye irritant, liver and kidney
damage
Ref: Physical Properties And Health Effects
of Pesticides Used On National Park Service Collections. Conserve
O Gram. U.S. National Park Service. September 2001. Number
2/17.
http://www.fluoridealert.org/pesticides/Natl.Park.Serv.Pesticides01.pdf
Liver
(click on for all fluorinated
pesticides)
In
long-term (chronic) feeding tests, hexaflumuron increased the
incidence and severity of a liver cell abnormality
(U.S. EPA. Office of Pesticide Programs. 1994. Pesticide fact
sheet: Hexaflumuron. Washington, D.C. Mar. 10).
Ref: Subterranean Termites. Part 2, by Caroline
Cox. Journal of Pesticide Reform / Summer 1997. Vol. 17, No. 2
http://www.pesticide.org/subtermites2.pdf
Abstract:
A toxicological evaluation of a new insecticide Sonet was realized.
It was established that by its toxicity Sonet belongs to hazardous
substances of class III. The main manifestations of its toxic
effect on the body warm-blooded animals is its influence on the
erythropoiesis and
functional state of the liver.
Ref: Sviatnyi IM et al. (1992). [A hygienic
evaluation of the insecticide Sonet and the characteristics of
the mechanism of its toxic action in an experiment] [Article in
Russian]. Lik Sprava. Jan;(1):84-7.
http://www.fluorideaction.org/pesticides/hexaflumuron.abstracts.htm
Definition:
Erythropoiesis is the process of
red blood cell production (which occurs in red bone marrow).
Environmental
(click
on for all fluorinated pesticides)
Hexaflumuron
is
very toxic to aquatic animals;
concentrations of 0.1 parts per billion kill water fleas
(US EPA. Office of Pesticide Programs. 1994. Pesticide fact
sheet: Hexaflumuron. Washington, D.C. (Mar. 10)). It is
persistent in soil, with a half-life (the time required
for breakdown of half the amount applied) between 100 and
160 days (Yon, D. et al. 1992. The environmental distribution
of hexaflumuron. Brighton Crop Protection Conference-Pests
and diseases-1992: 902-912.)
Ref: Subterranean Termites. Part 2,
by Caroline Cox. Journal of Pesticide Reform / Summer 1997.
Vol. 17, No. 2
http://www.pesticide.org/subtermites2.pdf
--
Environmental Bioconcentration: An estimated BCF of 4,700
was calculated for hexaflumuron(SRC), using a log Kow of
5.68(1) and a regression-derived equation(2). According
to a classification scheme(3), this
BCF suggests the potential for bioconcentration in aquatic
organisms is very high(SRC). [(1) Tomlin CDS, ed;
The Pesticide Manual World Compendium. 11th ed, Surrey,
England: British Crop Protection Council, p. 676 (1997)
(2) Meylan WM et al; Environ Toxicol Chem 18: 664-72 (1999)
(3) Franke C et al; Chemosphere 29: 1501-14 (1994)]
-- LD50
Bee oral & contact >0.1 mg/bee
[Tomlin, C.D.S. (ed.). The Pesticide Manual - World Compendium.
10th ed. Surrey, UK: The British Crop Protection Council,
1994. 564]
Ref: Hazardous Substances Data Bank
for HEXAFLUMURON CASRN: 86479-06-3 (online October 9, 2003).
Available at Toxnet.
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