Adverse Effects
Hexaflumuron
CAS No. 86479-06-3
 
 

Return to Hexaflumuron Index Page

Activity: Insecticide, Termiticide (Benzoylurea)
Structure:


Adverse Effects:
Blood
Eye
Kidney
Liver
Environmental

Hexaflumuron is a termiticide first registered in the US in 1994.

Hexaflumuron is the first active ingredient registered with the US EPA as a reduced-risk persticide. A reduced risk pesticide is one that EPA believes poses less risk to human health and the environment than existing alternatives.
Ref: Technical Fact Sheet for Hexaflumuron. National Pesticide Telecommunications Network.
http://ace.orst.edu/info/npic/factsheets/hextech.pdf


Blood (click on for all fluorinated pesticides)

Abstract: A toxicological evaluation of a new insecticide Sonet was realized. It was established that by its toxicity Sonet belongs to hazardous substances of class III. The main manifestations of its toxic effect on the body warm-blooded animals is its influence on the erythropoiesis and functional state of the liver.
Ref: Sviatnyi IM et al. (1992). [A hygienic evaluation of the insecticide Sonet and the characteristics of the mechanism of its toxic action in an experiment] [Article in Russian]. Lik Sprava. Jan;(1):84-7.

http://www.fluorideaction.org/pesticides/hexaflumuron.abstracts.htm

Definition: Erythropoiesis is the process of red blood cell production (which occurs in red bone marrow).

Eye (click on for all fluorinated pesticides)

Recruit (hexaflumuron) Health Effects: eye irritant, liver and kidney damage
Ref: Physical Properties And Health Effects of Pesticides Used On National Park Service Collections. Conserve O Gram. U.S. National Park Service. September 2001. Number 2/17.

http://www.fluoridealert.org/pesticides/Natl.Park.Serv.Pesticides01.pdf

Kidney (click on for all fluorinated pesticides)

Recruit (hexaflumuron) Health Effects: eye irritant, liver and kidney damage
Ref: Physical Properties And Health Effects of Pesticides Used On National Park Service Collections. Conserve O Gram. U.S. National Park Service. September 2001. Number 2/17.
http://www.fluoridealert.org/pesticides/Natl.Park.Serv.Pesticides01.pdf

Liver (click on for all fluorinated pesticides)

In long-term (chronic) feeding tests, hexaflumuron increased the incidence and severity of a liver cell abnormality (U.S. EPA. Office of Pesticide Programs. 1994. Pesticide fact sheet: Hexaflumuron. Washington, D.C. Mar. 10).
Ref: Subterranean Termites. Part 2, by Caroline Cox. Journal of Pesticide Reform / Summer 1997. Vol. 17, No. 2

http://www.pesticide.org/subtermites2.pdf

Abstract: A toxicological evaluation of a new insecticide Sonet was realized. It was established that by its toxicity Sonet belongs to hazardous substances of class III. The main manifestations of its toxic effect on the body warm-blooded animals is its influence on the erythropoiesis and functional state of the liver.
Ref: Sviatnyi IM et al. (1992). [A hygienic evaluation of the insecticide Sonet and the characteristics of the mechanism of its toxic action in an experiment] [Article in Russian]. Lik Sprava. Jan;(1):84-7.

http://www.fluorideaction.org/pesticides/hexaflumuron.abstracts.htm

Definition: Erythropoiesis is the process of red blood cell production (which occurs in red bone marrow).

Environmental (click on for all fluorinated pesticides)

Hexaflumuron is very toxic to aquatic animals; concentrations of 0.1 parts per billion kill water fleas (US EPA. Office of Pesticide Programs. 1994. Pesticide fact sheet: Hexaflumuron. Washington, D.C. (Mar. 10)). It is persistent in soil, with a half-life (the time required for breakdown of half the amount applied) between 100 and 160 days (Yon, D. et al. 1992. The environmental distribution of hexaflumuron. Brighton Crop Protection Conference-Pests and diseases-1992: 902-912.)
Ref: Subterranean Termites. Part 2, by Caroline Cox. Journal of Pesticide Reform / Summer 1997. Vol. 17, No. 2
http://www.pesticide.org/subtermites2.pdf

-- Environmental Bioconcentration: An estimated BCF of 4,700 was calculated for hexaflumuron(SRC), using a log Kow of 5.68(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is very high(SRC). [(1) Tomlin CDS, ed; The Pesticide Manual World Compendium. 11th ed, Surrey, England: British Crop Protection Council, p. 676 (1997) (2) Meylan WM et al; Environ Toxicol Chem 18: 664-72 (1999) (3) Franke C et al; Chemosphere 29: 1501-14 (1994)]
--
LD50 Bee oral & contact >0.1 mg/bee [Tomlin, C.D.S. (ed.). The Pesticide Manual - World Compendium. 10th ed. Surrey, UK: The British Crop Protection Council, 1994. 564]
Ref: Hazardous Substances Data Bank for HEXAFLUMURON CASRN: 86479-06-3 (online October 9, 2003). Available at Toxnet.

 
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