Adverse Effects
Ethalfluralin
CAS No. 55283-68-6
 
 

Return to Ethalfluralin Index Page

Activity: Herbicide (2,6-Dinitroaniline)
Structure:

 

Adverse Effects:
Ataxia
Bladder
Blood
Body Weight Decrease
Bone (including Cleft Palate)
Cancer: Possible Human Carcinogen - BREAST
, BLADDER, KIDNEY
Cholesterol
Clastogenic /Mutgenic
Developmental toxicant
Endocrine: Breast
Endocrine: Ovary
Kidney
Liver
Teratogen
Environmental

As of Febrtuary 14, 2005, this herbicide is permitted in or on 26 food commodities in the United States - see list at bottom of page.


Ataxia (click on for all fluorinated pesticides)

Short-term inhalation (1 to 7 days). Intermediate-term Inhalation (1 week to several months). Long-term inhalation (several months to lifetime). (Residential): Clinical signs included hypoactivity, dyspnea, ataxia, chromodacryorrhea, poor grooming, and yellow urine; these were reversible after 4 days (LC 50 0.94 mg/ L).
Ref: Federal Register. January 17, 2002. Ethalfluralin; Pesticide Tolerance. Final Rule.
http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Jan17.2002.htm

BLADDER (click on for all fluorinated pesticides)

Group C -- Possible Human Carcinogen. Mammary tumors (F); Suggestion of bladder tumors (F) and kidney tumors (M & F); Fischer 344 rats.
Ref:
April 26, 2006 . Chemicals Evaluated for Carcinogenic Potential by the Office of Pesticide Programs. From: Jess Rowland, Chief Science Information Management Branch Health Effect Division (7509C) Office of Pesticide Programs, USEPA.
http://www.fluorideaction.org/pesticides/pesticides.cancer.potential.2006.pdf

Blood (click on for all fluorinated pesticides)

1-year oral toxicity study in dogs. NOAEL = 4.0 mg/kg/day. LOAEL = 20 mg/kg/day based on altered red cell morphology and urinary bilirubin.
Ref: Federal Register: August 8, 2001. Ethalfluralin; Pesticide Tolerances for Emergency Exemptions. Final Rule.
http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Aug8.2001.htm

Chronic toxicity. Ethalfluralin was administered to Fisher 344 rats in the diet for 2 years in combined chronic toxicity and carcinogenicity replicate studies. The doses were equivalent to 0, 4.2, 10.7, or 32.3 mg/kg/day. The NOAEL for systemic effects was 32.3 mg/kg/ day. Mammary gland fibroadenomas were found in dosed female rats at statistically significant incidences in the mid and high doses. Ethalfluralin was administered to B6C3F1 mice in the diet for 2 years in combined chronic toxicity and carcinogenicity replicate studies. The doses were equivalent to 0, 10.3, 41.9, or 163.3 mg/kg/day. No increased incidence of neoplasms was attributed to the treatment. The NOAEL was 10.3 mg/kg/day. The mid dose (LOAEL) and high dose showed focal hepatocellular hyperplasia in both sexes. There were increased relative liver, kidney, and heart weights in females. Some
blood changes were found also, including decreased hematocrit, hemoglobin, and erythrocyte count accompanied by increased mean corpuscular hemoglobin concentration in high dose females. Alkaline phosphatase values were increased at the high dose in both sexes. Body weight gain decreased at the high dose.
Ref: Federal Register: November 14, 2001. [Notices] [Page 57082-57086]. Notice of Filing a Pesticide Petition to Establish a Tolerance for a Certain Pesticide Chemical in or on Food.

http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Nov14.2001.htm

Body Weight Decrease (click on for all fluorinated pesticides)

-- In the developmental toxicity study in rats, the maternal (systemic) NOAEL was 50 milligrams/ kilograms/day (mg/kg/day), based on decreased body weight gain and dark urine at the LOAEL of 250 mg/kg/day. The developmental (fetal) NOAEL was 1,000 mg/kg/day the highest dose tested (HDT).
-- In the developmental toxicity study in rabbits, the maternal (systemic) NOAEL was 75 mg/kg/day, based on abortions and decreased food consumption at the LOAEL of 150 mg/kg/day.
-- In a 3-generation reproductive toxicity study in rats, the parental (systemic) NOAEL was 12.5 mg/kg/ day, based on decreased mean body weight gains in males in all generations at the LOAEL of 37.5 mg/kg/day. The reproductive (pup) NOAEL was 37.5 mg/kg/day the HDT.
Ref: Federal Register: August 8, 2001. Ethalfluralin; Pesticide Tolerances for Emergency Exemptions. Final Rule.
http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Aug8.2001.htm

Ethalfluralin was evaluated for developmental toxicity. The test material was administered orally to 14, 13, 15, and 13 inseminated Dutch-Belted rabbits in doses of 0, 250, 500, and 750 mg/kg/day, respectively, on days 6-18 of gestation. Four, 9, and 7 rabbits of the 250, 500, and 750 mg/kg/day groups, respectively, aborted and were killed. Abortions were preceded by extended periods of anorexia and weight loss. Anorexia and substantial weight loss were observed during dosing at 250 mg/kg/day and above. Decreased live litter size and an increase in resorption incidence occurred at 500 and 750 mg/kg/day. No live fetuses were recovered at 750 mg/kg/day. No effects on sex distribution or weight were observed. No treatment related skeletal or visceral defects were observed. The authors concluded that maternal toxicity was observed at all dose levels. No teratogenicity was observed at any dose level.
Ref: 1992. INITIAL SUBMISSION: A TERATOLOGY STUDY WITH ETHALFLURALIN IN DUTCH-BELTED RABBITS WITH COVER LETTER DATED 08-21-92. ELI LILLY & CO. The National Technical Information Service. Report Number: NTIS/OTS0545185.

Ethalfluralin was evaluated for developmental toxicity. Fourteen, 11, and 14 pregnant Dutch-Belted rabbits were administered 0, 75, and 250 mg/kg/day of the test substance respectively, on days 6-18 of gestation. An increase in the number of anorectic rabbits occurred at 250 mg/kg/day. Four and 3 rabbits of the 75 and 250 mg/kg/day dose group, respectively, died or aborted. The abortions were preceded by anorexia and weight loss. Nine, 9, and 12 rabbits of the 0, 75, and 250 mg/kg/day dose groups were available for evaluation. Live litter size, resorption occurrence, fetal viability, and sex distribution were unaffected by treatment. Mean fetal weights of the treatment groups were lower than controls but the differences were not statistically significant. An increase in the incidence of skeletal abnormalities, including cleft palate and crooked ribs, was observed at 250 mg/kg/day. No treatment related visceral abnormalities were observed. The 250 mg/kg/day dose was maternally toxic but not teratogenic since the increased incidence of fetal defects was associated with anorexic dams. The 75 mg/kg/day dose was a no-effect level.
Ref: 1992. INITIAL SUBMISSION: A TERATOLOGY STUDY WITH ETHALFLURALIN IN DUTCH-BELTED RABBITS WITH COVER LETTER DATED 08-21-92. ELI LILLY & CO. The National Technical Information Service. Report Number: NTIS/OTS0545085.

Bone (click on for all fluorinated pesticides)

Beagle dogs were given 0, 4, 20, or 80 mg/kg/day orally, by capsule, for 1-year. The NOAEL was 4 mg/kg/day. The LOAEL was 20 mg/kg/ day, based on increased urinary bilirubin, variations in erythrocyte morphology, increased thrombocyte count, and increased erythroid series of the bone marrow. Elevated alkaline phosphatase levels were found at the two higher doses and siderosis of the liver at the high dose.
Ref: Federal Register. November 14, 2001. [PF-1052; FRL-6808-9] http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Nov14.2001.htm

-- Oral developmental toxicity study in rabbits. NOAEL = 75 mg/kg/day. LOAEL = 150 mg/kg/day based on an increased number of resorptions and increased sternal and cranial variations.
-- In the developmental toxicity study in rabbits, the maternal (systemic) NOAEL was 75 mg/kg/day, based on abortions and decreased food consumption at the LOAEL of 150 mg/kg/day. The developmental (fetal) NOAEL was also 75 mg/kg/day, based on a slightly increased number of resorptions, abnormal cranial development, and increased sternal variants at the LOAEL of 150 mg/kg/day.
Ref: Federal Register: August 8, 2001. Ethalfluralin; Pesticide Tolerances for Emergency Exemptions. Final Rule.

http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Aug8.2001.htm

Ethalfluralin was evaluated for developmental toxicity. Fourteen, 11, and 14 pregnant Dutch-Belted rabbits were administered 0, 75, and 250 mg/kg/day of the test substance respectively, on days 6-18 of gestation. An increase in the number of anorectic rabbits occurred at 250 mg/kg/day. Four and 3 rabbits of the 75 and 250 mg/kg/day dose group, respectively, died or aborted. The abortions were preceded by anorexia and weight loss. Nine, 9, and 12 rabbits of the 0, 75, and 250 mg/kg/day dose groups were available for evaluation. Live litter size, resorption occurrence, fetal viability, and sex distribution were unaffected by treatment. Mean fetal weights of the treatment groups were lower than controls but the differences were not statistically significant. An increase in the incidence of skeletal abnormalities, including cleft palate and crooked ribs, was observed at 250 mg/kg/day. No treatment related visceral abnormalities were observed. The 250 mg/kg/day dose was maternally toxic but not teratogenic since the increased incidence of fetal defects was associated with anorexic dams. The 75 mg/kg/day dose was a no-effect level.
Ref: 1992. INITIAL SUBMISSION: A TERATOLOGY STUDY WITH ETHALFLURALIN IN DUTCH-BELTED RABBITS WITH COVER LETTER DATED 08-21-92. ELI LILLY & CO. The National Technical Information Service. Report Number: NTIS/OTS0545085.

Cancer: Possible Human Carcinogen - BREAST, BLADDER, KIDNEY(click on for all fluorinated pesticides)

Group C -- Possible Human Carcinogen. Mammary tumors (F); Suggestion of bladder tumors (F) and kidney tumors (M & F); Fischer 344 rats.
Ref:
April 26, 2006 . Chemicals Evaluated for Carcinogenic Potential by the Office of Pesticide Programs. From: Jess Rowland, Chief Science Information Management Branch Health Effect Division (7509C) Office of Pesticide Programs, USEPA.
http://www.fluorideaction.org/pesticides/pesticides.cancer.potential.2006.pdf

Group C--Possible Human Carcinogen. Reviewed 9/ 14/ 94.
Ref: List of Chemicals Evaluated for Carcinogenic Potential. Science Information Management Branch, Health Effects Division, Office of Pesticide Programs, U. S. Environmental Protection Agency. March 15, 2002.
http://www.biomuncie.org/chemicals_evaluated_for_carcinog.htm

-- Combined chronic toxicity/ carcinogenicity in rats. NOAEL = 32.3 mg/kg/ day HDT. LOAEL = > 32.3 mg/ kg/day no systemic effects were seen at the HDT. Mammary gland fibroadenomas were found in dosed female rats at statistically significant incidences in mid and high doses.
-- Cancer (oral, dermal, inhalation). Ethalfluralin has been classified as a possible human carcinogen (Group C). Q1* = 8.9 x 10-2 (mg/kg/ day)-1. 2-year chronic carcinogenicity study in rats, showing an increased incidence of mammary gland fibroadenomas and combined adenomas/ fibroadenomas in female rats.
-- In vitro mammalian chromosome aberration test: In Chinese hamster ovary cells, ethalfluralin was negative without S9 activation, but it was clastogenic with activation.
Ref: Federal Register: January 17, 2002. Ethalfluralin; Pesticide Tolerance. Final Rule.

http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Jan17.2002.htm

-- EPA's Office of Pesticide Program's Carcinogenicity Peer Review Committee concluded that ethalfluralin should be classified as Group C, a possible human carcinogen, based on increased mammary gland fibroadenomas and adenomas/fibroadenomas combined in female rats. The tumor incidences were statistically significant at both the mid and high dose, and exceeded of the upper range of historical controls. Based on a low dose extrapolation, the Q1* of 8.9 x 10-2 (mg/kg/day)-1 has been calculated.
-- -- Cancer risk was estimated based on percent crop treated and anticipated residues as provided in EPA's Reregistration Eligibility Decision (RED) for ethalfluralin. Exposure to ethalfluralin from food is estimated to result in a lifetime cancer risk of 7.11 x 10-7. Cancer risks of less than 1 x 10-6 are generally considered to be negligible.
Ref: Federal Register. November 14, 2001. [PF-1052; FRL-6808-9]
http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Nov14.2001.htm

Chronic toxicity. Ethalfluralin was administered to Fisher 344 rats in the diet for 2 years in combined chronic toxicity and carcinogenicity replicate studies. The doses were equivalent to 0, 4.2, 10.7, or 32.3 mg/kg/day. The NOAEL for systemic effects was 32.3 mg/kg/day. Mammary gland fibroadenomas were found in dosed female rats at statistically significant incidences in the mid and high doses. EPA's Office of Pesticide Program's Carcinogenicity Peer Review Committee concluded that, ethalfluralin should be classified as Group C, a possible human carcinogen, based on increased mammary gland fibroadenomas and adenomas/fibroadenomas combined in female rats. The tumor incidences were statistically significant at both the mid and high dose, and exceeded the upper range of historical controls. Based on a low dose extrapolation, the Q1* of 8.9 x 10-2 (mg/kg/day)-1 has been calculated. Based on both registered and proposed product uses, exposure to ethalfluralin from food is estimated to not exceed a lifetime cancer risk of 8.47 x 10-7. Cancer risks of less than 1 x 10-6 are generally considered to be negligible.
Ref: Federal Register. August 31, 2005. Ethalfluralin; Notice of Filing a Pesticide Petition to Establish a Tolerance for a Certain Pesticide Chemical in or on Food.
http://www.fluorideaction.org/pesticides/ethalfluralin.fr.aug.2005.html

Cholesterol (click on for all fluorinated pesticides)

A three month oral study with beagle dogs had doses of 0, 6.25, 27.5, or 125/80 mg/kg/day by capsule. The systemic NOEL was 27.5 mg/kg/day. The systemic LOEL was 80 mg/kg/day (the high dose) based on elevated alkaline phosphatase, slight fatty metamorphosis of the liver, increased cholesterol, and increased BUN. (MRID 00135193)
Ref: US EPA. Reregistration Eligibility Decision (RED): Ethalfluralin. March 1995.
http://www.fluorideaction.org/pesticides/ethalfluralin.red.long.pdf

Clastogenic / Mutagenic (click on for all fluorinated pesticides)

Genotoxicty. Ethalfluralin was weakly mutagenic in activated strains TA1535 and TA100 of salmonella typhimurium, but not in strains TA1537, TA1538, and TA98 in an Ames assay. In a modified Ames assay with salmonella typhimurium and e- coli, ethalfluralin was weakly mutagenic in strains TA1535 and TA100, with and without activation, and in strain TA98 without activation, at the highest dose. No mutagenicity was found in the mouse lymphoma assay for forward mutation. Ethalfluralin did not induce unscheduled DNA synthesis in rat hepatocytes. In Chinese hamster ovary cells, ethalfluralin was negative without S9 activation, but it was clastogenic with activation.
Ref: Federal Register. November 14, 2001. [PF-1052; FRL-6808-9]
http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Nov14.2001.htm

Developmental toxicant (click on for all fluorinated pesticides)

-- Ethalfluralin is also a developmental toxicant based on a rabbit study... Dutch Belted rabbits were given 0, 25, 75, 150, or 300 mg/kg/day of ethalfluralin by gavage on gestation days 6-18. The NOELs for maternal and developmental toxicity were 75 mg/kg/day. The maternal LOEL at 150 mg/kg/day was based on abortions and decreased food consumption. These effects as well as decreased weight gain, enlarged liver, and orange urine were found at 300 mg/kg/day. In this study developmental toxicity was observed. The developmental LOEL was 150 mg/kg/day, based on slightly increased resorptions, abnormal cranial development, and increased sternal variants. (MRID 00129057)... Since developmental toxicity is the toxicological effect to which high end exposure is being compared in this analysis, the DRES subgroup of concern is females (13+ years) which approximates women of child-bearing age.
Ref: US EPA Reregistration Eligibility Decision (RED) Ethalfluralin. EPA 738-R-95-001. March 1995.
http://www.fluoridealert.org/pesticides/Ethalfluralin.RED.Long.pdf

Endocrine: Breast (click on for all fluorinated pesticides)

Group C -- Possible Human Carcinogen. Mammary tumors (F); Suggestion of bladder tumors (F) and kidney tumors (M & F); Fischer 344 rats.
Ref:
April 26, 2006 . Chemicals Evaluated for Carcinogenic Potential by the Office of Pesticide Programs. From: Jess Rowland, Chief Science Information Management Branch Health Effect Division (7509C) Office of Pesticide Programs, USEPA.
http://www.fluorideaction.org/pesticides/pesticides.cancer.potential.2006.pdf

-- Combined chronic toxicity/ carcinogenicity in rats. NOAEL = 32.3 mg/kg/ day HDT. LOAEL = > 32.3 mg/ kg/day no systemic effects were seen at the HDT. Mammary gland fibroadenomas were found in dosed female rats at statistically significant incidences in mid and high doses.
-- Cancer (oral, dermal, inhalation). Ethalfluralin has been classified as a possible human carcinogen (Group C). Q1* = 8.9 x 10-2 (mg/kg/ day)-1. 2-year chronic carcinogenicity study in rats, showing an increased incidence of mammary gland fibroadenomas and combined adenomas/ fibroadenomas in female rats.
-- In vitro mammalian chromosome aberration test: In Chinese hamster ovary cells, ethalfluralin was negative without S9 activation, but it was clastogenic with activation.
Ref: Federal Register: January 17, 2002. Ethalfluralin; Pesticide Tolerance. Final Rule.

http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Jan17.2002.htm

EPA's Office of Pesticide Program's Carcinogenicity Peer Review Committee concluded that ethalfluralin should be classified as Group C, a possible human carcinogen, based on increased mammary gland fibroadenomas and adenomas/fibroadenomas combined in female rats. The tumor incidences were statistically significant at both the mid and high dose, and exceeded of the upper range of historical controls. Based on a low dose extrapolation, the Q1* of 8.9 x 10-2 (mg/kg/day)-1 has been calculated.
Ref: Federal Register. November 14, 2001. [PF-1052; FRL-6808-9] http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Nov14.2001.htm

Endocrine: Ovary (click on for all fluorinated pesticides)

-- In vitro mammalian chromosome aberration test: In Chinese hamster ovary cells, ethalfluralin was negative without S9 activation, but it was clastogenic with activation.
Ref: Federal Register: January 17, 2002. Ethalfluralin; Pesticide Tolerance. Final Rule.

http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Jan17.2002.htm

KIDNEY (click on for all fluorinated pesticides)

Group C -- Possible Human Carcinogen. Mammary tumors (F); Suggestion of bladder tumors (F) and kidney tumors (M & F); Fischer 344 rats.
Ref:
April 26, 2006 . Chemicals Evaluated for Carcinogenic Potential by the Office of Pesticide Programs. From: Jess Rowland, Chief Science Information Management Branch Health Effect Division (7509C) Office of Pesticide Programs, USEPA.
http://www.fluorideaction.org/pesticides/pesticides.cancer.potential.2006.pdf

Liver (click on for all fluorinated pesticides)

Beagle dogs were given 0, 4, 20, or 80 mg/kg/day orally, by capsule, for 1-year. The NOAEL was 4 mg/kg/day. The LOAEL was 20 mg/kg/ day, based on increased urinary bilirubin, variations in erythrocyte morphology, increased thrombocyte count, and increased erythroid series of the bone marrow. Elevated alkaline phosphatase levels were found at the two higher doses and siderosis of the liver at the high dose.
Ref: Federal Register. November 14, 2001. [PF-1052; FRL-6808-9] http://www.fluoridealert.org/pesticides/Ethalfluralin.FR.Nov14.2001.htm

-- Subchronic toxicity studies using mice and rats resulted in changes in liver and kidney weights, decreased weight gain, and changes in blood and enzyme activity. A study using beagle dogs resulted in changes in the liver, blood and cholesterol..
-- A chronic toxicity and carcinogenicity study using rats resulted in mammary gland tumors in female rats at mid and high doses. EPA concluded on June 8, 1994, that ethalfluralin should be classified as a Group C, possible human carcinogen, based on the results of that study. A second study in mice caused liver cell, blood and enzyme changes, as well as increased liver, kidney and heart weights in females, and decreased body weight gain. A study using beagle dogs resulted in changes in the blood, bone marrow, enzymes and liver.
Ref: January 1995. US EPA R.E.D. FACTS Ethalfluralin.
http://www.fluorideaction.org/pesticides/ethalfluralin.red.epa.1995.pdf

Teratogen (click on for all fluorinated pesticides)

Ethalfluralin was evaluated for developmental toxicity. Fourteen, 11, and 14 pregnant Dutch-Belted rabbits were administered 0, 75, and 250 mg/kg/day of the test substance respectively, on days 6-18 of gestation. An increase in the number of anorectic rabbits occurred at 250 mg/kg/day. Four and 3 rabbits of the 75 and 250 mg/kg/day dose group, respectively, died or aborted. The abortions were preceded by anorexia and weight loss. Nine, 9, and 12 rabbits of the 0, 75, and 250 mg/kg/day dose groups were available for evaluation. Live litter size, resorption occurrence, fetal viability, and sex distribution were unaffected by treatment. Mean fetal weights of the treatment groups were lower than controls but the differences were not statistically significant. An increase in the incidence of skeletal abnormalities, including cleft palate and crooked ribs, was observed at 250 mg/kg/day. No treatment related visceral abnormalities were observed. The 250 mg/kg/day dose was maternally toxic but not teratogenic since the increased incidence of fetal defects was associated with anorexic dams. The 75 mg/kg/day dose was a no-effect level.
Ref: 1992. INITIAL SUBMISSION: A TERATOLOGY STUDY WITH ETHALFLURALIN IN DUTCH-BELTED RABBITS WITH COVER LETTER DATED 08-21-92. ELI LILLY & CO. The National Technical Information Service. Report Number: NTIS/OTS0545085.

Environmental (click on for all fluorinated pesticides)

Ecological Effects
-- ... Technical ethalfluralin is highly to very highly toxic to rainbow trout and bluegill sunfish. The formulated product also is highly toxic to bluegill sunfish. Since ethalfluralin persists in soils and is very highly toxic to fish, an acute toxicity sediment study was submitted. This study shows that ethalfluralin released from soil sediments can be lethal to sunfish when concentrations in water reach 17 to 58 parts per billion (ppb). In an early life stage toxicity test with freshwater fish, ethalfluralin affected larval length and weight in trout. In invertebrate toxicity studies, technical ethalfluralin is very highly toxic and the formulated product is slightly toxic to Daphnia magna on an acute basis. In a life cycle study using daphnids, reproduction was the most sensitive parameter affected. Ethalfluralin is highly toxic to marine/estuarine fish, mollusks, and shrimp on an acute basis...
Ecological Effects Risk Assessment
-- ... Ground applications of ethalfluralin could result in potential risks to aquatic organisms from runoff and drift. Although neither high acute risk nor chronic risk to aquatic organisms is anticipated, the restricted use trigger has been exceeded for freshwater organisms, and endangered species triggers are exceeded for freshwater organisms and estuarine/marine invertebrates.
-- Endangered species levels of concern are exceeded for freshwater organisms and estuarine/marine invertebrates from unincorporated applications; for freshwater fish from incorporated applications; and for plants growing in wet areas receiving channelized runoff from treated sites (from unincorporated applications). Limitations may be imposed on the use of ethalfluralin to protect threatened and endangered species when EPA implements the Endangered Species Protection Program, later in 1995.

Ref: US EPA. Reregistration Eligibility Decision (RED): Ethalfluralin. March 1995.
http://www.fluorideaction.org/pesticides/ethalfluralin.red.long.pdf


A February 14, 2005, check at the Code of Federal Regulations for Ethalfluralin: this herbicide is permitted in or on 26 food commodities.

[Code of Federal Regulations]
[Title 40, Volume 22]
[Revised as of July 1, 2004]
From the U.S. Government Printing Office via GPO Access
[CITE: 40CFR180.416]
[Page 439]

TITLE 40--PROTECTION OF ENVIRONMENT

CHAPTER I--ENVIRONMENTAL PROTECTION AGENCY (CONTINUED)

PART 180_TOLERANCES AND EXEMPTIONS FROM TOLERANCES FOR PESTICIDE CHEMICALS
IN FOOD--Table of Contents

Subpart C_Specific Tolerances

Sec. 180.416 Ethalfluralin; tolerances for residues.
(a) General. Tolerances are established for residues of the
herbicide ethalfluralin [N-ethyl-N-(2-methyl-2-propenyl)-2,6-dinitro-4-
(trifluoromethyl)benzenamine] in or on the following raw agricultural commodities:
Commodity

As of September 26, 2003

PPM

As of September 10, 2004

PPM

As of
February 14, 2005

PPM

US Code of Federal Regulations

CFR

Bean, dry, seed Not listed this way Not listed this way 0.05 180.416
BEAN, DRY 0.05 0.05 Not listed this way 180.416
BEAN, DRY 0.05 Not listed Not listed this way/duplicate not listed 180.416
Canola, seed 0.05 0.05 0.05 180.416
CANOLA, SEED 0.05 Not listed Duplicate not listed 180.416
CANOLA, SEED 0.05 0.05 Duplicate not listed 180.416B
CANOLA, SEED 0.05 Not listed Duplicate not listed 180.416B
CUCURBITS 0.05 Not listed this way Not listed this way 180.416
CUCURBITS 0.05 0.05 Not listed this way/duplicate not listed 180.416
GOAT, FAT - Not listed Not listed 180.416
GOAT, FAT - Not listed Not listed 180.416
GOAT, MEAT - Not listed Not listed 180.416
GOAT, MEAT - Not listed Not listed 180.416
GOAT, MEAT BYPRODUCTS - Not listed Not listed 180.416
GOAT, MEAT BYPRODUCTS - Not listed Not listed 180.416
Pea, dry, seed Not listed this way Not listed this way 0.05 180.416
PEA, DRY 0.05 0.05 Not listed this way 180.416
PEA, DRY 0.05 Duplicate not listed Duplicate not listed 180.416
Peanut 0.05 0.05 0.05 180.416
PEANUT 0.05 Not listed Duplicate not listed 180.416
Safflower, seed 0.05 0.05 0.05 180.416
SAFFLOWER, SEED 0.05 Duplicate not listed Duplicate not listed 180.416
SAFFLOWER, SEED 0.05 0.05 Duplicate not listed 180.416B
SAFFLOWER, SEED 0.05 Duplicate not listed Duplicate not listed 180.416B
Soybean 0.05 0.05 0.05 180.416
SOYBEAN 0.05 Duplicate not listed Duplicate not listed 180.416
Sunflower, seed 0.05 0.05 0.05 180.416
SUNFLOWER, SEED 0.05 Duplicate not listed Duplicate not listed 180.416

Vegetable, cucurbit, group 9

This group includes 19 commodities:
balsam apple
balsam pear
cantaloupe
chayote, fruit
cucumber
cucumber, chinese
cucurbits
gherkin, west indian
gourd, edible
melon
melon, citron
muskmelon
pumpkin
squash
squash, summer
squash, winter
vegetable, cucurbit, group
watermelon
waxgourd, chinese

Not listed Not listed 0.05 180.416
(b) Section 18 emergency exemptions. [Reserved]
(c) Tolerances with regional registrations. [Reserved]
(d) Indirect or inadvertent residues. [Reserved]

 

 
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