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Activity: Herbicide
(Benzimidazole)
Structure:
Adverse
Effects:
Liver
•
No toxicological information available.
Major Uses:
HERBICIDE
[Farm Chemicals Handbook 1993. Willoughby,
OH: Meister Publishing Co., 1993.,p. C-76]
Metabolism/Metabolites:
YIELDS 4,5-DICHLORO-6-HYDROXY-2-TRIFLUOROMETHYLBENZIMIDAZOLE
& 4,5-DICHLORO-7-HYDROXY-2-TRIFLUOROMETHYLBENZIMIDAZOLE
IN RABBIT & RAT. /FROM TABLE/
[Goodwin, B.L. Handbook of Intermediary
Metabolism of Aromatic Compounds. New York: Wiley, 1976.,p.
D-26]
FORMERLY MANUFACTURED BY
FISONS LTD.
[Farm Chemicals Handbook 1984. Willoughby,
Ohio: Meister Publishing Co., 1984.,p. C-51]
Ref: Hazardous
Substances Data Bank
for CHLOROFLUORAZOLE - CASRN: 3615-21-2 (Note
spelling)
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Liver
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Animal Toxicity Studies:
Non-Human Toxicity Excerpts: ... AN UNCOUPLER OF OXIDATIVE PHOSPHORYLATION
CAUSING 50% UNCOUPLING OF RAT LIVER MITOCHONDRIAL
OXIDATIVE PHOSPHORYLATION AT 6X10-7 MOLAR ALSO STIMULATING
ATPASE ACTIVITY & CELL RESPIRATION. [Spencer, E. Y. Guide to the
Chemicals Used in Crop Protection. 7th ed. Publication 1093. Research
Institute, Agriculture Canada, Ottawa, Canada: Information Canada,
1982. 107]
Ref: TOXNET profile from Hazardous Substances
Data Bank for CHLOROFLUORAZOLE.
http://www.fluoridealert.org/pesticides/chlorfluorazole.toxnet.hsdb.htm
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