Dichlorotetrafluoroethane (Cryofluorane)
CAS No. 76-14-2
 
 

Return to Dichlorotetrafluoroethane Adverse Effects

ACTIVITY: Propellant, Former EPA List 2 Inert

Structure:

Adverse Effects:

Brain
Carcinogen
CNS
Heart
Lung

Environmental Effects:

Ozone depleting substance 

Regulatory Information
(only comprehensive for the US)
US EPA Registered: Yes, in use as of April 28, 2004.
Former EPA List 2 Inert 
US EPA PC Code: 326200 
California Chemical Code 3115 
Other Information
Molecular Formula: C2Cl2 F4  
Manufacturers: DuPont 
Other Names: 
1,2-Dichloro-1,1,2,2-tetrafluoroethane
Cryofluorane
Dichlorotetrafluoroethane [USAN]
Freon 114
CFC-114
Dichlorotetrafluoroethane
Ethane, 1,2-dichlorotetrafluoro-
Refrigerant 114
1,1,2,2-Tetrafluoro-1,2-dichloroethane
Of special interest:
PAN BAD ACTOR - Carcinogen
TOXNET profile from Hazardous Substances Data Bank 
2000 - Toxic Release Inventory. Brief Summary.
June 24, 1998. Former List 2 Inert. Inert Ingredients No Longer Used in Pesticide Products. US EPA, Federal Register.
Occupational Safety and Health Guideline - OSHA.  
June 21, 2001 - Hazardous Materials Regulations for Fluoride/fluorinated substances, Federal Register on Harmonization of international shipment of Dangerous Goods. Final Rule. 
Chemical Profile - Scorecard, Environmental Defence Fund 

US EPA List of Inerts. This substance was formerly on List 2.

Note: US EPA allows so-called "Inert" ingredients to be commonly mixed with the "active" pesticidal ingredient to create a formulated pesticide product. According to EPA, "The term `inert' is not intended to imply nontoxicity; the ingredient may or may not be chemically active." "Inert" ingredients include solvents, emulsifiers, spreaders, and other substances mixed into pesticide products to increase the effectiveness of the active ingredients, make the product easier to apply, or to allow several active ingredients to mix in one solution. Both US EPA and California Department of Pesticide Regulation require pesticide manufacturers to identify inert ingredients in their products but do not disclose this information to the general public because the pesticide industry considers product formulations trade secrets, protected by law and by the US EPA. The US EPA category of Inerts (as of September 2003):

List 1 - Of Toxicological Concern
List 2 - Potentially Toxic / High Priority for Testing
List 3 - Of Unknown Toxicity
List 4A - Generally Regarded as Safe
List 4B - EPA states it has Sufficient Information to Reasonably Conclude that the Current Use Pattern in Pesticide Products will not Adversely Affect Public Health or the Environment
List 4 (all)

See good report: Toxic Secrets": "Inert" Ingredients in Pesticides 1987-1997, published by Northwest Coalition for Alternatives to Pesticides.


US Federal Register
Date Published Docket Identification Number Details
August 3, 2005 OPP-2005-0068

Inert ingredients; Revocation of Pesticide Tolerance Exemptions for Three CFC Chemicals. FINAL RULE.
EPA is revoking exemptions from the requirement of a tolerance for three inert ingredients (dichlorodifluoromethane, dichlorotetrafluoroethane, and trichlorofluoromethane) because these substances no longer have active Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) pesticide product registrations and/or because their use in pesticide products sold in the United States (U.S.) has been prohibited under the Clean Air Act (CAA) for over a decade due to EPA's ban on the sale or distribution, or offer for sale or distribution in interstate commerce of certain nonessential products that contain or are manufactured with ozone depleting compounds...
Nonetheless, EPA will establish and maintain tolerances and tolerance exemptions even when corresponding domestic uses are canceled if the tolerances, which EPA refers to as ``import tolerances,'' are necessary to allow
importation into the United States of food containing such pesticide residues.
However, where there are no imported commodities that require these import tolerances, the Agency believes it is appropriate to revoke tolerances and tolerance exemptions for unregistered pesticide chemicals in order to prevent potential misuse.

40 CFR chapter I is amended as follows:
PART 180--[AMENDED]
• 1. The authority citation for part 180 continues to read as follows:
Authority: 21 U.S.C. 321(q), 346a and 371.
• 2. Section 180.910 is amended by removing the following exemptions and
any associated Limits and Uses from the table: Dichlorodifluoromethane,
Dichlorotetrafluoroethane, and Trichlorofluoromethane.
• 3. Section 180.930 is amended by removing the following exemptions and
any associated Limits and Uses from the table: Dichlorodifluoromethane
and Trichlorofluoromethane.

April 27, 2005 OPP-2005-0068

Inert Ingredients; Proposal to Revoke Pesticide Tolerance.
EPA is proposing to revoke exemptions from the requirement of a tolerance for three inert ingredients (dichlorodifluoromethane, dichlorotetrafluoroethane, and trichlorofluoromethane) because these
substances are no longer in active Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) pesticide product registrations and/or their use in pesticide products sold in the U.S. has been prohibited under the Clean Air Act for over a decade by EPA's ban on the sale or distribution, or offer for sale or distribution in interstate commerce
of certain nonessential products that contain or are manufactured with ozone depleting compounds.
These ingredients are subject to reassessment by August, 2006 under section 408(q) of the Federal Food,
Drug, and Cosmetic Act (FFDCA), as amended by the Food Quality Protection Act of 1996 (FQPA).

Therefore, it is proposed that 40 CFR part 180 be amended as follows:
PART 180--AMENDED
1. The authority citation for part 180 continues to read as follows:
Authority: 21 U.S.C. 321(q), 346a and 371.
Sec. 180.910 [Amended]
2. Section 180.910 is amended by removing the following exemptions
and any associated Limits and Uses from the table:
Dichlorodifluoromethane, Dichlorotetrafluoroethane, and
Trichlorofluoromethane.
Sec. 180.930 [Amended]
3. Section 180.930 is amended by removing the following exemptions
and any associated Limits and Uses from the table:
Dichlorodifluoromethane and Trichlorofluoromethane.

April 28, 2004 OPP-2003-0368 Pesticides; Tolerance Exemptions for Active and Inert Ingredients for Use in Antimicrobial Formulations (Food-Contact Surface Sanitizing Solutions). FINAL RULE.
-- Propellant - used in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest. 
June 24, 1998 OPP- 36192

Inert Ingredients No Longer Used in Pesticide Products - Former List 3 Inert.

EPA is removing certain chemicals from its list of pesticide product inert ingredients that are not currently used in pesticide products. Future use of these chemicals as inert ingredients in pesticide products will not be permitted unless a petitioner or registrant satisfies all data requirements as identified by the Agency, and the Agency is able to make a determination that the use of the inert ingredient will not pose unreasonable risk to human health or the environment. All tolerances or exemptions from the requirement of a tolerance for the use of these chemicals as inert ingredients in food- use pesticide formulations will be proposed for revocation at a later date in a separate Federal Register Notice.

 
Fluoride Action Network | Pesticide Project | 315-379-9200 | pesticides@fluoridealert.org